Compounding Basics Flashcards
1
Q
Hazardous drugs
A
Carcinogenic
Teratogenic
Genotoxic
Toxic to organs @ low doses
2
Q
Air pressure
A
Negative (Hazardous drugs)
Positive (non-HD)
3
Q
Air changes
A
12 ACPH non-sterile HDs
30 ACPH sterile HDs
4
Q
Air quality
A
((ISO rating-1)=N (number of integers)
352 + 1 zero equal to N-3
5
Q
Gloved fingertip test
A
Conducted annually (low-med risk), biannual (high risk) 3 passed tests initially (0 CFU) Done with tryptic soy agar
6
Q
Media-Fill Test
A
Conducted with tryptic soy broth
No turbulence after 14d
7
Q
Temperature
A
Monitor daily
20°C (68°F) in SEC
2-8°C (36-46°F) Fridge
-50-(-15)°C (-58-(-5)°F) Freezer
8
Q
Air sampling
A
Biannual
Check gauge daily
9
Q
Surface sampling
A
Conducted with TSA sprayed with polysorbate 80 and lecithin
<3 CFU ISO 5
<5 CFU ISO 7
10
Q
Deactivation and decontamination
A
2% Bleach (Sodium Hypochlorite)
Peroxide
11
Q
Disposal
A
Sharps (red bin)
Trace chemo (yellow bin)
Bulk chemo (black bin)
