Component Preparation Flashcards

1
Q

What are the biochemical changes associated with loss of RBC viability

A
increase in plasma K+
decrease in plasma Na+
increase in plasma HGB
decrease in ATP
decrease in 2,3-DPG
decrease in pH
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2
Q

What is the expiration date fo blood drawn in ACD

A

21 days

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3
Q

What is the expiration date fo blood drawn in CPD

A

21 days

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4
Q

What is the expiration date fo blood drawn in CPDA

A

35 days

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5
Q

What is the expiration date fo blood drawn in ADSOL

A

42 days

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6
Q

What temperature should whole blood be stored at?

A

1-6C

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7
Q

What is the basic transfusion requirements for whole blood

A

must be ABO specific/Rh compatible

must be XM compatible

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8
Q

What is the shelf life, storage temp, volume, content, and Txn criteria for packed cells in ADSOL

A
42 days 
1-6C
300mL
rbcs, wbc, small amounts of plasma
XM required; ABO compatible required
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9
Q

What is the shelf life, storage temp, volume, content, and Txn criteria for leukoreduced packed cells

A

42 days at 1-6C
300ml
rbc, small amount plasma
XM required, abo compatible required

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10
Q

What is the shelf life, storage temp, volume, content, and Txn criteria for washed packed red cells

A

24 hours at 1-6C
250ml
rbcs
xm required; ABO compatible required

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11
Q

What is the shelf life, storage temp, volume, content, and Txn criteria for frozen/ deglyced cells

A
24 hours thawed or 10 years frozen
1-6C thawed or below -65C for frozen
200ml
rbcs
XM required ABO compatible required
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12
Q

What is the shelf life, storage temp, volume, content, and Txn criteria for random platelets

A
5 days
RT with agitation 
50ml
plt, plasma, wbc
ABO compatible preferred
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13
Q

What is the shelf life, storage temp, volume, content, and Txn criteria for random platelet pooled

A
4 hours
RT with agitation 
250-500ml
plt, plasma, wbc
ABO compatible preferred
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14
Q

What is the shelf life, storage temp, volume, content, and Txn criteria for apheresis platelets

A
5 days
RT with agitation 
300-500ml
plt, plasma, wbc
ABO compatible preferred
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15
Q

What is the shelf life, storage temp, volume, content, and Txn criteria for AFFP FFP PF24 frozen

A
1 year
less than -18C
500ml, 250ml
coag clotting factors, plasma
ABO compatible preferred
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16
Q

What is the shelf life, storage temp, volume, content, and Txn criteria for FFP, PF24 thawed

A
5 days
1-5C
250ml
stable coag factors 
ABO compatible preferred
17
Q

What is the shelf life, storage temp, volume, content, and Txn criteria for AFFP thawed

A
24 hours
1-6C
500ml
labile and stable factors 
ABO compatible preferred
18
Q

What is the shelf life, storage temp, volume, content, and Txn criteria for cryo frozen

A
1 year
less than -18C
15ml
VIII, VWF, XIII, fibrinogen
ABO compatible preferred
19
Q

What is the shelf life, storage temp, volume, content, and Txn criteria for cryo thawed

A
6 hours
RT
15ml
VIII, VWF, XIII, fibrinogen
ABO compatible preferred
20
Q

What is the shelf life, storage temp, volume, content, and Txn criteria for cryo thawed and pooled

A
4 hours
RT
75-100ml
VIII, VWF, XIII, fibrinogen
ABO compatible preferred
21
Q

What is the QC requirements for WBC count of leukoreduced products

A

< 5x10^6 WBC

22
Q

What is the QC requirements for platelet count of apheresis platelets

A

3x10^11 PLT

23
Q

What is the QC requirements for platelet count of random platelet concentratrate

A

5.5x10^10 PLT

24
Q

What is the QC requirements for minimum pH of platelets

A

6.2 pH

25
Q

What is the QC requirements for maximum HCT of packed cells

A

80%

26
Q

What is the QC requirements for fibrinogen content in cryo

A

150mg

27
Q

What is the QC requirements for factor VIII content in cryo

A

80 IU