Component Preparation Flashcards

1
Q

Collection of blood in a sterile blood container

A

Closed system

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2
Q

Collection or exposure to air through open ports that would shorten the expiration because of potential bacterial contamination

A

Open system

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3
Q

The volume of anticoagulant-preservative solutions in the primary collection bag

A

63-70mL (63mL for 450+/- 45mL blood drawn;

70 mL for 500+/- 50mL blood drawn)

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4
Q

Considered as Red blood cells low volume

A

300-404 mL of whole blood in an anticoagulant volume calculated for 450+/- 45mL;

333-449 mL of whole blood in an anticoagulant volume calculated for 500+/-50mL

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5
Q

Components discarded for low volume units

A

Platelets, FFP, Cryoprecipitate AHF,

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6
Q

Storage lesion: Increase & Decrease

A

Increase: Plasma K+, Plasma Hemoglobin, NH4
Decrease: Viable cells, Plasma pH, Plasma Na+, RBC ATP & 2,3 DPG

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7
Q

The storage limit for CPD (Citrate - phosphate-dextrose)

A

21 days

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8
Q

The storage limit for CP2D (Citrate-phosphate-2-dextrose)

A

21 days

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9
Q

The storage limit for CPDA-1 (Citrate-phosphate-dextrose-adenine)

A

35 days

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10
Q

The storage limit for AS-1, AS-3, AS-5, AS-7

A

42 days

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11
Q

RBCs prepared from blood collected in CPDA-1 should have a hematocrit level of ___

A

=80% HCT

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12
Q

An anticoagulant-preservative chemical that prevents coagulation by chelating calcium

A

Citrate

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13
Q

Storage temperature for Whole blood, RBCs, WRBCs / deglycerolized RBCs, Irradiated RBCs

A

1-6C

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14
Q

Storage temperature for Frozen RBCs

A

-65C

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15
Q

Expiration limit for Frozen RBCs with CPD / CPDA-1 additive

A

10 years

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16
Q

Storage temperature(s) for FFP, and corresponding expiration limits

A

= -18C : 1 yr.

= -65C : 7 yrs.

17
Q

Platelets should be stored at ___ with continuous ___.

A

20-24C with continuous agitation

18
Q

A buffered salt solution that replaces a portion of the plasma to store platelets

A

PAS (Platelet Additive Solution)

19
Q

Storage temperature of thawed plasma and expiration limit

A

1-6C; 5 days from thawing

20
Q

Whole blood is prepared with a ratio of __ mL anticoagulant preservative solution per ___ mL of whole blood.

A

14 mL anticoagulant preservative solution per 100 mL of whole blood

21
Q

Components of whole blood

A

RBCs, WBCs, platelets, plasma proteins, and anticoagulant-preservative solution

22
Q

Whole blood is administered to patients who are actively bleeding and have lost more than __% of their blood volume.

A

25%

23
Q

Whole blood increases the hemoglobin by __g/dL, or the hematocrit by ___%

A

Hgb: 1g/dL
Hct: 3%

(1:3)

24
Q

This is the cold insoluble precipitate that forms when a unit of FFP is thawed between 1C and 6C. It contains most of the coagulation factors that are found in FFP.

A

Cryoprecipitated Antihemophilic Factor (AHF) / CRYO

25
Q

Light spin utilizes short time and low RPM which yields __.

A

PRP (platelet-rich plasma)

26
Q

Heavy spin utilized longer spin and high RPM which yields __.

A

Concentrated component

27
Q

Component prepared for a patient with sickle cell disease

A

RBCs

28
Q

Component prepared for a patient with thrombocytopenia

A

Platelets

29
Q

Component prepared for a patient with Hemophilia A

A

Factor VIII Concentrate

30
Q

Component prepared for a patient with Fibrinogen Deficiency

A

Cryoprecipitated AHF

31
Q

Eight units of platelets were pooled in an open system without the use of a sterile connecting device (open system). What is the new time of expiration of the pooled product?

A

4 hrs.

32
Q

How many platelets must be obtained in a plateletpheresis in order to meet acceptance criteria?

A

3.0x10^11

33
Q

Shipping temperature for RBCs

A

1-10C

34
Q

ABO incompatibility is acceptable for what component/s?

A

Cryoprecipitated AHF