Complications of Sedation Flashcards
What were the adverse findings of the Rapid Response report?
Bolus sedation still used
Untrained seditionists
Incorrect doses given- incorrect labels/concentration
Reliance on flumazenil
What is the bolus technique?
this is where the drug is put in at one time rather than slowly and gradually by titration while checking regularly
What is the only concentration of midazolam used?
1mg/1ml
When should flumazenil be used?
Used in an emergency to reverse effect of midazolam only
Should not be used to speed up recovery
Should not be relied on with practitioners wrongly choosing to over-sedate patient on purpose
What is the ultimate complication of sedation?
Death
Extremely rare
Would be due abuse or excessive levels/incorrect doses of drug given
What are the complications of cannulation in IV sedation?
Venospasm
Extravascular injection
Intra-arterial injection
Haematoma
Fainting
What is venospasm? (disappearing vein syndrome)
Veins collapse at attempted venepuncture (Associated with poorly visible veins)
-> May be accompanied by burning
How is venospasm prevented?
Using tourniquet/vein tapping to help dilate vein
Gravity
Warm water/gloves
Quicker puncture
What occurs in an extra-vascular injection?
Active drug placed into interstitial space
-> Pain/swelling
-> can result in delayed absorption
How is EVI prevented?
Good cannulation
Test dose of saline (flush)
How is EVI treated?
Remove cannula
Apply pressure
Reassure
Which artery is most commonly affected by intra-arterial injection?
Brachial artery
What are the signs of an IA injection?
Pain on venepuncture
Red blood in cannula
Difficult to prevent leaks
Pain radiating distally from site of cannulation
Loss of colour or warmth to limb / weakening pulse (as artery could constrict and blood supply could be stopped)
How can IA injections be prevented?
Always stay superficial
Artery walls are thicker- puncture is thicker
Prevent by going lateral to bicep tendon
Palpate to check if vessel has pulse (if positive it is not a vein)
How is an IA injection treated?
Monitor for loss of pulse- Cold/Discolouration
Leave cannula in situ for 5 mins post drug
No problems – remove
Symptomatic- leave and refer to hospital (procaine 1%)
What can happen if diazepam is giving intra-arterially?
Necrosis