Complications of Conscious Sedation in Dentistry Flashcards

1
Q

Historically what factors contributed to complications of conscious sedation in dentistry?

A
  • bolus sedation used
  • untrained seditionists
  • incorrect doses given
    • mixed up labels
    • incorrect concentration
  • reliance on flumazenil
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2
Q

What are the possible complications of cannulation?

A
  • venospasm
  • extravascular injection
  • intraarterial injection
  • haematoma
  • fainting
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3
Q

What is venospasm?

A
  • disappearing vein syndrome
    • increased with poor technique
      • must ensure good dilation
      • quick insertion
  • vein collapse at attempted venipuncture
    • on insertion of cannula
  • may be accompanied by burning
  • associated with poorly visible veins
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4
Q

How is venospasm managed?

A
  • dilating vein
    • should be well dilated
    • worse with repeated attempts
  • efficient technique
    • slow puncture makes worse
  • warm water/gloves
    • better vasodilation
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5
Q

What is extravascular injection?

A
  • active drug placed into interstitial space
    • cannula not inserted into vein
  • symptoms
    • pain
    • swelling
      • liquid bubbles up in tissue
  • delayed absorption
    • delayed sedation
      • 20-30 minutes
    • drug still absorbed so treatment must be delayed
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6
Q

How is extravascular injection managed?

A
  • prevention
    • good cannulation
    • test dose of saline
      • ensures in vein
  • treatment
    • remove cannula
    • apply pressure
    • reassure
      • midazolam is non-irritant
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7
Q

What is intra-arterial injection?

A
  • cannulation of artery
    • often brachial artery if antecubital fossa
      • must cannulate lateral to bicep tendon
    • high blood pressure can push cannula out
  • symptoms
    • pain on venepuncture
      • thicker artery wall
      • radiates distal to cannulation site
    • red blood in cannula
    • difficult to prevent leaks
    • loss of colour or warmth to limb
    • visible or weakened pulse
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8
Q

How are intra-arterial injections managed?

A
  • prevention
    -insert lateral to bicep tendon
    - if antecubital fossa cannulation
    • palpate before insertion
  • management
    • monitor for loss of pulse
      • cold
      • discolouration
    • leave cannula in situ for 5 minutes post drug
    • if no problems, remove
    • if symptomatic leave
      • refer to hospital
      • administer procaine 1%
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9
Q

What is a haematoma and how does it occur because of cannulation?

A
  • extravasation of blood into soft tissues
    • damage to vein walls
  • can occur at venipuncture
    • poor technique
    • puncture both side of vein
      • blood pooling
  • can occur at removal of cannula
    • failure to apply pressure
  • particularly common in elderly patients
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10
Q

How can haematoma be prevented?

A
  • good cannulation technique
    • avoid multiple holes in vein wall
  • pressure post-operatively
    • operator should apply, not patient
    • 2-3 minutes afterwards
  • take care with elderly
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11
Q

How can haematoma be treated?

A
  • time
  • rest
  • reassurance
  • in severe cases
    • initially apply ice pack
    • moist heat for 20 minutes
      • after 24 hours
    • consider heparin gel
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12
Q

Why can fainting occur during venepuncture?

A
  • anxiety related to venepuncture
  • low blood sugar
    • anxious patients may not eat
    • increased chance of fainting
  • accompanied by shaking or tremoring
  • urinary incontinence is possible
    • bowel incontinence is not a faint
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13
Q

How can fainting during venepuncture be managed?

A
  • prevention
    • encourage patients to eat
    • topical anaesthesia
  • management
    • lie patient down
    • raise legs
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14
Q

What are the possible complications of drug administration during intravenous sedation?

A
  • hyper-response
  • hypo-response
  • paradoxical reactions
  • over sedation
  • allergic reactions
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15
Q

What is considered a hyper-response to intravenous sedation and how is it managed?

A
  • deep sedation with minimal dose
    • 1-2mg midazolam
  • care with titration
    • reason for 1mg increments
    • even slower with elderly
      • very sensitive
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16
Q

What is considered a hypo-response to intravenous sedation and how is it managed?

A
  • little sedative effect with large doses
  • check cannula is in vein
  • may be due to tolerance
    • benzodiazepine induced
      • BDZ, drug users/addicts, methadone
    • cross tolerance
    • idiopathic
  • maximum doses
    • 15mg in hospital settings
    • 7.5mg in general practice
17
Q

What are paradoxical reactions to intravenous sedations and how are they managed?

A
  • patients appear to sedate normally
  • react extremely to all stimuli
    • relax when stimuli removed
  • check for failure of LA
  • do not give further sedative
    • find alternative management technique
    • consider flumazenil
  • special care for immature teenagers
18
Q

What is oversedation?

A
  • loss of responsiveness
    • unable to tell patient to take deep breaths
  • respiratory depression
    • respiratory centres acted on by drug
    • pulse oximeter used at all times
      • below 90% give oxygen
  • loss of ability to maintain airway
  • respiratory arrest
    • patient stops breathing
19
Q

How is over sedation managed?

A
  • stop procedure
  • try to rouse patient
  • continually assess ABC
  • if no response to stimulation
    • reverse with flumazenil
      • 200ug initially
      • 100ug increments every minute
    • watch for 1-4 hours
      • aware of re-sedation risk
  • be more careful next time
20
Q

How can respiratory depression be managed?

A
  • check pulse oximeter
  • stimulate patient
    • ask to take deep breaths
  • supplemental oxygen
    • nasal cannulae
    • 2l per minute
  • reverse with flumazenil
21
Q

What allergic reactions can occur in response to sedation and how should they be managed?

A
  • very rare to have allergy to sedative
  • if benzodiazepine allergy:
    • do not give flumazenil
      • also benzodiazepine
  • consider latex and Elastoplast allergies
  • deliver adrenaline
    • IM injection to thigh
22
Q

How might sedation result in sexual fantasy?

A
  • sedation can feel like being drunk
    • aetiology and incidence unknown
      • documented but uncommon
    • no way to prevent
  • all patients must be chaperoned at all times
23
Q

What is the elimination half-life of midazolam and how long does it remain in the body?

A
  • elimination half life
    • 1-2 hours
  • in body
    • 12 hours
24
Q

What are the distribution half life, recovery period and working period of midazolam?

A
  • distribution half life
    • 15 minutes
  • recovery period
    • 1 hour
  • working time
    • 45 minutes
25
Q

What are the complications of inhalation sedation?

A
  • oversedation
    • patient discomfort
    • lack of cooperation
    • mouth breathing
    • giggling
    • nausea
    • vomiting
    • loss of consciousness
  • patient panics
    • panic attack
    • spinning sensation
    • reassure patient
    • abort sedation if cannot cope
  • chronic exposure
    • nitrous oxide
      • problems with Vitamin B12
      • pregnancy
      • numbness