Complications of assisted reproductive technology treatment and the factors influencing reproductive outcome TOG 2018

Question 1

How common is mild OHSS/severe OHSS

Answer 1

Mild 1/3
Sever 1-2%

Question 2

Increased risk of multiple pregnancy with ART?

Answer 2

2- x

Question 3

Which factors increase risk monozygotic twins?

Answer 3

Blastocyst transfer
ICSI

Question 4

HFEA target of multiple pregnancy in IVF?

Answer 4

10%

Question 5

Rate of ectopic pregnancy following ART?

Answer 5

2-9%
Vs 1-2% natural conception

Question 6

Risk of heterotypic pregnancy following ART?

Answer 6

8/1000 ART
Background 1/30,000

Question 7

Is ART linked to early menopause?

Answer 7

No

Question 8

Perinatal outcomes following IVF

Answer 8

Higher rates of LBW, shorter duration of pregnancy & increased risk of SGA, perinatal mortality.

Question 9

What is the impact of ART and risk of congenital abnormality?

Answer 9

30-40% increased risk of congenital abnormality

5% risk → 6.5-7.0%

Question 10

What proportion of people undergoing IVF remain childless?

Answer 10

50%

Question 11

What is the strongest predictor of ART?

Answer 11

Female age

If donor egg - irrespective of recipient age group

Question 12

How does the number of oocytes retrieved effect live birth rate

Answer 12

Increases up to 15, plates then decreases from 10

Question 13

What stage embryo has better live birth rates>

Answer 13

Blastocyst
Higher embryo quality