Complex inheritance and Personalized Medicine

Question 1

Silent polymorphism

Answer 1

1. Small insertions/deletions, differences in the number repeats or single nucleotide differences (SNPs) that have no functional difference.

Question 2

Functional Polymorphism

Answer 2

Small insertions/deletions, differences in the number repeats or single nucleotide differences (SNPs) that are function and affect either expression of the gene or activity of the protein

Question 3

Relative risk

Answer 3

Prevalence of the disease in the relatives of an affected person/ prevalence of the disease in the general population