Complement Flashcards
Complement
A system of serum and cell surface proteins that generate effectors of immune responses through a cascade of interactions.
Classical pathway
Complement system activation by the formation of antigen-antibody complexes.
Alternative pathway
spontaneous complement system activation on pathogen cell surfaces
Lectin binding pathway
Complement system activation by polysaccharide residues on pathogens
Membrane attack complex (MAC)
The terminal components of complement that form pores in the membranes of target cells
Opsonin
An agent that binds to an antigen to tag it for phagocytosis
Anaphylatoxin
Complement component that is capable of triggering degranulation in mast cells and basophils to induce local and systemic inflammatory responses.