Complement Flashcards

1
Q

Complement

A

A system of serum and cell surface proteins that generate effectors of immune responses through a cascade of interactions.

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2
Q

Classical pathway

A

Complement system activation by the formation of antigen-antibody complexes.

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3
Q

Alternative pathway

A

spontaneous complement system activation on pathogen cell surfaces

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4
Q

Lectin binding pathway

A

Complement system activation by polysaccharide residues on pathogens

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5
Q

Membrane attack complex (MAC)

A

The terminal components of complement that form pores in the membranes of target cells

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6
Q

Opsonin

A

An agent that binds to an antigen to tag it for phagocytosis

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7
Q

Anaphylatoxin

A

Complement component that is capable of triggering degranulation in mast cells and basophils to induce local and systemic inflammatory responses.

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