Community Onset Infectious Diseases

Question 1

What is immunity to influenza mediated by?

Answer 1

IgG and IgA antibodies against haemagglutinin

Question 2

What does H and N stand for in terms of influenza?

Answer 2

Haemagglutinin and neuraminidase

Question 3

What is the mechanism of action of oseltamivir?

Answer 3

A neuraminidase inhibitor

Question 4

What is the benefit of oseltamivir?

Answer 4

Reduces illness duration by 17 hours, reduces pneumonia, reduces influenza in contacts

Question 5

Which pathogens cause a secretory diarrhoea?

Answer 5

Vibrio cholera
ETEC
EPEC
Rotavirus
Norovirus
Giárdia
Cryptosporidium

Question 6

Which pathogens cause an inflammatory diarrhoea?

Answer 6

Shigella
Salmonella
Campylobacter
Yersinia
STEC
EAEC
c. diff
entamoeba histolytica

Question 7

What is the incubation period of b. cereus?

Answer 7

1-6 hours

Question 8

What is the incubation period of norovirus?

Answer 8

10-48 hours

Question 9

Which diarrhoeal pathogen is associated with GBS?

Answer 9

Campylobacter

Question 10

Which diarrhoeal pathogen is associated with reactive arthritis?

Answer 10

Campylobacter, salmonella, shigella, Yersinia

Question 11

What is the treatment for moderate c. diff?

Answer 11

Metronidazole 400mg Q8H or vancomycin 125mg Q6H for 10 days

Question 12

What is the treatment for fulminant c. diff?

Answer 12

Vancomycin 500mg Q6H with IV metronidazole

Question 13

What is the treatment for first recurrence c. diff?

Answer 13

PO vancomycin or fidaxomicin

Question 14

What is the treatment for multiple recurrences of c. diff?

Answer 14

Faecal microbiota transplant

Question 15

What is the treatment for moderate to severe travellers diarrhoea?

Answer 15

Azithromycin 1g stat or ciprofloxacin 750mg stat