communicable diseases,disease prevention and the immune system Flashcards
common features of bacteria?
A fast rate of reproduction
Treated with antibiotics
e.g bacterial meningitis
Common features of fungi
Larger then bacteria
Generally live on the surfaces of organisms by growing a skin called the mycelium
Reproduce by releasing spores
Common features of protists
Single celled
major protist born pathogens are Pintophoraa
and plasmodium
common features of viruses’
Cannot reproduce themselves so not organism
Exceptionally small
Mutate quickly
Invade a host cell
name transmission routes
Faecal oral
Direct
Airborne
Indirect
Vectoral
Describe tuberculosis
A bacterial disease caused by mycobacterium
that damages lung tissue and suppresses immune system
Describe bacterial meningitis
caused by bacteria streptococcus pneumonia
leads to blood poisoning or red rashes
Describe Ring Rot
caused by gram positive bacteria
Damages leaves and rots tubers and fruit
Describe HIV/AIDS
human immunodeficiency virus- by attacking the immune system and leads to severe illness
Describe Influenza
A viral infection of the nose throat and lungs
Caused by orthomyxonious genus
what evidence is there that antibodies have a quaternary protein structure
they have 4 poly peptides
Explain why antibodies only join to specific antigens
antibodies have a variable region that has a specific amino acid sequence OR primary structure
the shape OR tertiary structure of the binding site is complementary to specific antigens
forms a complex between the antigen and antibody OR forms an antigen-antibody complex
Describe how phagocytosis occurs
engulfs/endocytosis
forms a vesicle/phagosome AND fuses with a lysosome
enzymes/lysozymes digest/hydrolyse the pathogen
what is an antigen?
a glycoprotien on the membrane
that stimultates an immune response
During the immune response, phagocytes present a pathogen’s antigens on their cell surface.
Describe how presentation of antigens leads to the release of antibodies against these antigens.
helper T cell OR TH cell binds to the antigen on the phagocyte
helper T cell OR TH cell stimulates a specific B cell
B cell clones OR B cell divides by mitosis
forms plasma cells that release antibodies
Explain how the release of antibodies stimulates the process of phagocytosis.
antibodies bind to antigens
OR
antibodies are markers/opsonins
OR
antibodies form antigen-antibody complexes
antibodies cause clumping/agglutination
OR
antibodies attract phagocytes
what are the direct forms of transmission?
direct contact
innoculation e.g sharing needles
ingestion e.g eating infected foods
what are the indirect forms of transmission?
vectors
airborne transmission
formites e.g dirty clothes
what is autoimmune disease?
body produces self-recognising T cells which produce a signal of body cells as infected cells or pathogens
describe the antibody structure
has two binding sites
variable regions are complementary to antigens
has four polypeptide chains called immunoglobnins
what role does the T lymphocyte play in the immune system?
recognises antigens displayed on phagocytes and stimulate specific t killer cells and B cells to divide by mitosis for the specific immune response
what are physical defences of plants?
waxy cuticle -forms a physical barrier
cell wall- also performs as a physical barrier
production of callose- When plants are attacked by pathogens they produce a polysaccharide called callose. This is deposited between the cell wall and the cell-surface membrane to make it harder for pathogens to enter cells.
what are chemical defences of plants?
Insect repellents - These reduce the number of insects feeding on plants to prevent them from transmitting pathogens.
Insecticides - These kill insects to prevent them from transmitting pathogens.
Antibacterial substances - Chemicals such as antibiotics are produced to kill bacteria or inhibit their growth.
Toxins - Some plants produce chemicals that break down into cyanide (a toxic chemical) when the plant cells are attacked.
what are opsonin’s?
they are markers for antigen presenting cells to make it easier for phagocytes to recognise a pathogen