communicable diseases,disease prevention and the immune system Flashcards

1
Q

common features of bacteria?

A

A fast rate of reproduction
Treated with antibiotics
e.g bacterial meningitis

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2
Q

Common features of fungi

A

Larger then bacteria
Generally live on the surfaces of organisms by growing a skin called the mycelium
Reproduce by releasing spores

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3
Q

Common features of protists

A

Single celled
major protist born pathogens are Pintophoraa
and plasmodium

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4
Q

common features of viruses’

A

Cannot reproduce themselves so not organism
Exceptionally small
Mutate quickly
Invade a host cell

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5
Q

name transmission routes

A

Faecal oral
Direct
Airborne
Indirect
Vectoral

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6
Q

Describe tuberculosis

A

A bacterial disease caused by mycobacterium
that damages lung tissue and suppresses immune system

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7
Q

Describe bacterial meningitis

A

caused by bacteria streptococcus pneumonia
leads to blood poisoning or red rashes

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8
Q

Describe Ring Rot

A

caused by gram positive bacteria
Damages leaves and rots tubers and fruit

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9
Q

Describe HIV/AIDS

A

human immunodeficiency virus- by attacking the immune system and leads to severe illness

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10
Q

Describe Influenza

A

A viral infection of the nose throat and lungs
Caused by orthomyxonious genus

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11
Q

what evidence is there that antibodies have a quaternary protein structure

A

they have 4 poly peptides

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12
Q

Explain why antibodies only join to specific antigens

A

antibodies have a variable region that has a specific amino acid sequence OR primary structure

the shape OR tertiary structure of the binding site is complementary to specific antigens

forms a complex between the antigen and antibody OR forms an antigen-antibody complex

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13
Q

Describe how phagocytosis occurs

A

engulfs/endocytosis

forms a vesicle/phagosome AND fuses with a lysosome

enzymes/lysozymes digest/hydrolyse the pathogen

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14
Q

what is an antigen?

A

a glycoprotien on the membrane
that stimultates an immune response

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15
Q

During the immune response, phagocytes present a pathogen’s antigens on their cell surface.

Describe how presentation of antigens leads to the release of antibodies against these antigens.

A

helper T cell OR TH cell binds to the antigen on the phagocyte

helper T cell OR TH cell stimulates a specific B cell

B cell clones OR B cell divides by mitosis

forms plasma cells that release antibodies

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16
Q

Explain how the release of antibodies stimulates the process of phagocytosis.

A

antibodies bind to antigens

OR

antibodies are markers/opsonins

OR

antibodies form antigen-antibody complexes

antibodies cause clumping/agglutination

OR

antibodies attract phagocytes

17
Q

what are the direct forms of transmission?

A

direct contact
innoculation e.g sharing needles
ingestion e.g eating infected foods

18
Q

what are the indirect forms of transmission?

A

vectors
airborne transmission
formites e.g dirty clothes

19
Q

what is autoimmune disease?

A

body produces self-recognising T cells which produce a signal of body cells as infected cells or pathogens

20
Q

describe the antibody structure

A

has two binding sites
variable regions are complementary to antigens
has four polypeptide chains called immunoglobnins

21
Q

what role does the T lymphocyte play in the immune system?

A

recognises antigens displayed on phagocytes and stimulate specific t killer cells and B cells to divide by mitosis for the specific immune response

22
Q

what are physical defences of plants?

A

waxy cuticle -forms a physical barrier
cell wall- also performs as a physical barrier
production of callose- When plants are attacked by pathogens they produce a polysaccharide called callose. This is deposited between the cell wall and the cell-surface membrane to make it harder for pathogens to enter cells.

23
Q

what are chemical defences of plants?

A

Insect repellents - These reduce the number of insects feeding on plants to prevent them from transmitting pathogens.
Insecticides - These kill insects to prevent them from transmitting pathogens.
Antibacterial substances - Chemicals such as antibiotics are produced to kill bacteria or inhibit their growth.
Toxins - Some plants produce chemicals that break down into cyanide (a toxic chemical) when the plant cells are attacked.

24
Q

what are opsonin’s?

A

they are markers for antigen presenting cells to make it easier for phagocytes to recognise a pathogen

25
what are cytokines
released after phagocytosis which signals other phagocytes to move to the site of infection
26
in the cellular response,clonal expansion means many types of T-cells describe the different types of T cells
T helper cells These cells have receptors on their cell-surface that bind to complementary antigens on antigen-presenting cells. They produce interleukins (a type of cytokine) which stimulate B cells or phagocytes. T helper cells can also form memory cells or T killer cells. T killer cells These cells kill abnormal and foreign cells by producing a protein known as perforin. This protein makes holes in the cell-surface membrane, causing it to become freely permeable and causing cell death. T regulator cells These cells suppress the immune system after pathogens have been destroyed. This helps to prevent the immune system from mistakenly attacking the body cells. T memory cells These cells provide long-term immunity against specific pathogens. They provide a rapid response if the body is re-infected by the same pathogen.
27
what is a parasite?
lives , in / on , host ; gains nutrition / feeds , from (host) ; at the expense of / harms (host) ;
28
explain why the body's primary defence cannot prevent infection from a parasite?
vector feeds on blood and breaks through the skin
29
what is an antigen?
a glycoprotien that stimuates an immune response
30
Some strains of bacteria that cause meningitis are resistant to multiple antibiotics. Discuss the consequences of this resistance for health authorities.
Increased further spread increased cost as it requires more complex treatment fewer antibiotics are resistant against menigitisis