commonalities Flashcards

1
Q

CNS depressants CI

A
  • muscle relaxants (carisoprodol, cyclobenzaprine, methocarbamol, diazepam)
  • benzodiazepines (alprazolam, diazepam)
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2
Q

MAO-I CI

A
  • SSRIs (escitalopram, fluoxetine, paroxitine)
  • TCAs (amitryptyline)
  • dextromethorphan
  • nasal decongestnats (pseudoephedrine, phenylephrine, oxymetazoline)
  • albuterol
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3
Q

category x

A
  • phentermine
  • misoprostal
  • nitrofurantoin (3rd trimester)
  • alprostadil
  • oxytocin
  • HcG
  • bicalutamide
  • clomiphene
  • isoretinoin
  • megesterol
  • finasteride
  • testosterone
  • estrogens
  • levonorgesterol
  • medroxyprogesterone
  • northindrone
  • raloxifen
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4
Q

Drugs that can cause pulmonary fibrosis

A
  • Amiodarone (class III antiarrhytmic: heart block, hypotension, hypo/hyperthyroid, hepatotoxicity, coronary skin deposits also possible)
  • bromocriptine (indicated for PD, acromegaly, hyperprolactinemia)
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5
Q

alkylating agents used in cancer treatment

A
  • cisplatin, used in mets testicular and ovarian CA, also adv. bladder CA
  • cyclophosphamide, used in leukemia, lymphomas
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6
Q

drugs known to cause Steven Johnson syndrome

A
  • modafinal ( used to treat narcolepsy)

* terbinafine

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7
Q

drugs known to be hepatotoxic

A
amiodarone (arrhytmias)
Isoniazid (TB)
propylthiouracil (thyroid storm)
rifampin (TB)
terbinafine (onchomycosis)
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8
Q

drugs that change urine color

A

Methocarbamol (black, blue, green urine)

rifampin (red tears/saliva/ urine)

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9
Q

drugs CI due to sulfa allergies

A

Furosemide
HCTZ
Glyburide
sulfasalazine

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10
Q

drugs CI with concomitant EtOH use

A

acetaminophen

Metronidazole

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11
Q

common estrogen in combo OCPs

A

Ethinyl estradiol
+ drospirenone
+ norelgestromin
+ noregestimate

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12
Q

onset of insulins

A

lispro < regular < glargine

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13
Q

non-selective cox inhibitors

A

aspirin (I: fever, pain, inflammation, platelet agg.)
diclofenac (I: topical inflammation)
ketorlac (I: pain)

ibuprofen
indomethacin
naproxen (I inflammation)
nepafenac (I: post-cataract)

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14
Q

drugs that affect microtubule assembly

A

albendazole and mebendazole (anti-helminthic)

colchicine (I: gout)

vinblastine (I: hodgkin’s, testicular CA, kaposi’s sarcoma)

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15
Q

DMPS and DMSA commonly chelate

A

mercury

arsenic

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16
Q

difference between DMPS and DMSA in chelating I.

A

DMPS: gold

DMSA: lead, antimony

Both: mercury, arsenic

17
Q

anticholinergics

A

Atropine (I: mydriatic, organophosphate poisoning, PD, bradycardia)

Benztropine, Scopolamine, Diphenhydramine (I: dyskinesia in PD)

hyoscyamine, dicyclomine (I: diarrhea, IBS, spasms, PUD)

scopalmine (I: motion sickness)