Common Skin Conditions - Acne

Question 1

List drugs that can discolor skin or secretions brownish

Answer 1

Levodopa

Entacapone

Methyldopa

Question 2

List drugs that can discolor skin or secretions purple/orangish/reddish

Answer 2

Chlorzoxazone

Question 3

List drugs that can discolor skin or secretions orange/yellowish

Answer 3

Sulfasalazine

Question 4

List drugs that can discolor skin or secretions brownish/yellowish

Answer 4

Nitrofurantoin

Riboflavin (B12)

Question 5

List drugs that can discolor skin or secretions blueish

Answer 5

Mitoxantrone

Methylene blue

Question 6

List drugs that can discolor skin or secretions orange/reddish/brownish

Answer 6

Ezogabine

Question 7

List drugs that can discolor skin or secretions brown/black/greenish

Answer 7

Methocarbamol

Question 8

List drugs that can discolor skin or secretions yellow-greenish

Answer 8

Propofol

Flutamide

Question 9

List drugs that can discolor skin or secretions red-orangeish

Answer 9

Phrnazopyridine

Rifapentine

Rifampin

Question 10

List drugs that can discolor skin or secretions reddish

Answer 10

Anthracyclines

Question 11

What’s the primary determinant of acne?

Answer 11

Androgens (male sex hormones) which is why boys often have worse acne than girls

Question 12

List other factors that may contribute to acne

Answer 12

Presence of the bacteria P. acnes + fatty acids present in oil glands

Question 13

List the 4 primary grps of acne agents

Answer 13

OTC (benzoyl peroxide and salicylic acid)

Retinoids

Systemic isotretinion

Antibiotics

Question 14

What’s the most effective OTC acne agent?

Answer 14

Benzoyl peroxide (BPO)

Question 15

What’s the usual rx drug of choice?

Answer 15

Retinoids, primarily topical tretinoin

Question 16

How long does it usually take for retinoids to start working?

Answer 16

4-12 weeks

Acne may worsen initially

Question 17

What’s usually given concurrently with retinoids to help with the worsening acne from initial retinoid use?

Answer 17

Antibiotic, usually Minocycline

Question 18

What’s the brand name of Tretinoin microsphere gel?

Answer 18

Retin-A Micro

Question 19

What’s the brand name of Tretinoin Polymerized cream or gel?

Answer 19

Avita

Question 20

What’s the brand name of Adaplene?

Answer 20

Differin

Question 21

How do u use retinoids?

Answer 21

A pea-sized amount is sufficient

Divide it into 4 equal parts

Smooth over the entire surface of the face- not just on acne

Question 22

What should be avoided with Tretinoin use, especially while starting a retinoid (Retin-A Micro; Avita; Adapalene (Differing))? Why?

Answer 22

Avoid salicylic acid scrubs or astringents

May worsen irritation

Question 23

How often should face be washed?

Answer 23

Wash with mild soap twice a day

Question 24

T/F? Limit sun exposure while using retinoids (Retin-A Micro; Avita; Adapalene (Differing))?

Answer 24

True

Question 25

What's the preferred combo for acne?

Answer 25

Benzaclin (BPO) + 1% Clindamycin (Duac)

Question 26

List clindamycin topicals

Answer 26

Cleocin T ClindaMax lotion/soln Clindagel Evoclin foam Benzamycine and Benzaclin

Question 27

Howz Benzamycin and Benzaclin stored?

Answer 27

Benzamycin - refrigerated Benzaclin - room temp

Question 28

What's the indication for oral isotretinion?

Answer 28

Only for tx of severe recalcitrant nodular acne

Question 29

Contraceptions and oral isotretinion?

Answer 29

2 forms of birth control is required (NOT the mini pill)

Question 30

What's a bothersome side effect of oral isotretinion?

Answer 30

DRYNESS Carry bottled water, eye drops and lip balm

Question 31

What's required b4 females can start oral isotretinion?

Answer 31

Must have 2 negative pregnancy test prior to starting tx

Question 32

What meds are CI with oral isotretinion concurrently?

Answer 32

Vit A supplements Tetracyclines Steroids Progestin-only contraceptives St. John's wort

Question 33

What's the preg category of oral isotretinion?

Answer 33

Cat X Severe birth defects/ miscarriages

Question 34

Where can oral isotretinion be dispensed?

Answer 34

Can only be dispensed by a pharmacy registered and activated with the pregnancy risk mgt IPLEDGE program

Question 35

Which oral antibiotic is commonly used in acne?

Answer 35

Minocycline ext-rel (Solodyn)

Question 36

What's the brand name of Minocycline ext-rel (most commonly used Antiobiotic in acne)?

Answer 36

Solodyn

Question 37

What other antibiotics are used for acne?

Answer 37

Doxycycline Trimethoprim-Sulfamethoxazole

Question 38

Is Aloe a natural pdt?

Answer 38

Yes