Common medicines, DMARDs and Biologics

Question 1

What is used to treat atherosclerosis?

Answer 1

Statins

Question 2

What is used to treat hypertension?

Answer 2

B-blockers
Diurectics
ACE inhibitors
Angiotensin 2 antagonists
Calcium channel blockers

Question 3

Examples of B-blockers

Answer 3

Bisoprolol

Atenalol

Question 4

Example of diurectic

Answer 4

Bendroflumethiazide

Question 5

Example of ACE inhibitor

Answer 5

Ramipril

Question 6

Example of Angiotensin 2 antagonist

Answer 6

Valsartan

Question 7

Example of Calcium Channel blocker

Answer 7

Amlodipine

Nifedipine

Question 8

What is used to treat Ischaemic heart disease?

Answer 8

Anti-platelets
Cholesterol / Statins 
B-blockers
Calcium channel blockers
Nitrates
Others / Nicorandil

Question 9

Example of anti-platelet

Answer 9

Clopidogrel

Aspirin

Question 10

Example of Nitrate

Answer 10

GTN

Isosrbide mononitrate

Question 11

What is used to treat heart failure?

Answer 11

Diuretics
ACE inhibitors/ angiotensin 2 receptor antagonists
B-blockers
Digoxin

Question 12

What is used to treat Valvular heart disease?

Answer 12

Anti-coagulants - warfarin, dipyridamole

Question 13

What is used to treat Arrhythmias

Answer 13

Anti-coagulants e.g. warfarin, rivaroxaban 
Calcium Antagonists 
Digoxin
Amiodarone 
B-blockers

Question 14

What medications are associated with MRONJ?

Answer 14

Bisphosphonates
Denosumab
Anti-angiogenics

Question 15

Asthma medication

Answer 15

Short acting beta 2 antagonist 
Steroids
Long acting beta 2 antagonist 
Anti leukotrienes 
Systemic steroids

Question 16

Example of short acting beta 2 antagonist

Answer 16

Salbutamol

Question 17

Example of steroid inhalor (2)

Answer 17

Beclometasone

Fluticasone

Question 18

Example of long acting beta 2 antagonist

Answer 18

Salmeterol

Question 19

Example of Anti-leukotienes

Answer 19

Montelukast

Question 20

Example of systemic steroids

Answer 20

Prednisolone

Question 21

What is used to treat COPD

Answer 21

Short acting beta 2 antagonist
Short acting muscarinic antagonists
Long acting beta 2 antagonist
Long acting muscarinic antagonist 
Steroid inhaler 
Mucolytic 
Systemic steroids
Antibiotic

Question 22

Short acting beta 2 antagonist

Answer 22

Salbutamol

Question 23

Short acting muscarinic antagonist

Answer 23

Ipatropium

Question 24

Long acting beta 2 antagonist

Answer 24

Salmeterol

Question 25

Long acting muscarinic antagonist

Answer 25

Tiotropium

Question 26

Steroid inhaler

Answer 26

Fluticasone | Beclometasone

Question 27

Mucolytic

Answer 27

Carbocisteine

Question 28

Systemic steroid

Answer 28

Prednisolone

Question 29

Antibiotic

Answer 29

Azithromycin

Question 30

Management of autoimmune diseases

Answer 30

``` Early diagnosis Symptom control - pain Corticosteroids DMARDs Others - physiotherapy ```

Question 31

Possible side effects of corticosteroids?

Answer 31

``` Cushing's syndrome Osteoporosis prophylaxis Candidosis MRONJ Prophylaxis ```

Question 32

What does DMARD stand for?

Answer 32

Disease modifying anti rheumatic drug

Question 33

List examples of DMARDs

Answer 33

``` Methotrexate Ciclosporin Hydroxychloroquine Azathioprine Mycophenolate mofetil Sulfasalazine Gold (sodium aurothiomalate) Leflunomide ```

Question 34

How often is methotrexate taken?

Answer 34

Once per week | Orally or subcutaneous injection

Question 35

Side effects of methotrexate

Answer 35

Mouth ulcers, neutropenia, thrombocytopenia, abN LFTs, pneumonitis

Question 36

Which supplement may be required?

Answer 36

Folic acid

Question 37

Monoclonal antibody therapy is given to which group of PTs?

Answer 37

Those who have "failed" therapy with at least 2 DMARDs

Question 38

Examples of TNF alpha inhibitors

Answer 38

``` Adalimumab Certolizumab Etanercept Infliximab Golimumab ```

Question 39

Interleukin inhibitors

Answer 39

Tocilizumab | Ustekinumab

Question 40

T-cell activation inhibitors

Answer 40

Abtacept

Question 41

Anti-B lymphocyte

Answer 41

Rituximab

Question 42

Antineoplastic

Answer 42

Cetuximab

Question 43

What risk comes with taking monoclonal antibody therapy?

Answer 43

Double risk of serious infections for patients | Side effects - heart failure, lupus-like, demyelination, skin cancer, dental infections