Common Gen Surgery Issues Flashcards
What do general surgeons do? (13 organs)
stomach pancreas gallbladder intestine appendix adrenals spleen adipose thyroid breast lymphatics soft tissue carcinoma
Serum proteins & nutritional profile indicates_____
degree of illness & perioperative morbidity
Half life of: Albumin Pre-albumin Transferrin Retinol Binding Protein
Albumin: 21 days
Pre-Albumin: 2-3 days
Transferrin: 8 days
Retinol Binding Protein: 12 hours
Ebb Phase: when does it occur, what is it, energy supply/demand, metabolism, hormones
first 24-72 hours
non-stressed starvation
basal energy requirements are decreased
& supplied by LIVER & MUSCLE GLYCOGEN STORES
then switch to fatty acids and ketones for energy & stop burning muscle protein as much
↓metabolism
- catecholamine release
- norepinephrine release
Flow phase: when does it occur, characteristics
Catabolic & Anabolic-peaks 3-5 dyas
HYPERMETABOLIC, HYPERGLYCEMIC
subsides 7-10 days & merges with anabolic phase
high cardiac output, restoration of oxygen delivery & metabolic sustrate
Blood glucose level post surgery
it is common for people to have hyperglycemia post-surgery
Hypermetabolic phase: net result (3) control what to what range, why?
net result: negative nitrogen balance, ↓adipose stores, hyperglycemia
control of hyperglycemia [at least below 150 (80-150mg/dl)] is important to limit complication & ↓morbidity and mortality
Normal caloric needs, protein needs
‘stressed’ patient needs
Kcal/gram in: protein, carbs, fat
normal:
25-30 kcal/kg/day
0.8-1g protein/kg/day
‘stressed’:
50 kcal/kg/day
2.5 protein/kg/day
Protein: 4 Kcal/gm
Carbs: 3.4 Kcal/gm
Fat: 9 Kcal/gm
Enteral nutrition is done via
"if the gut works, use it" feeding tubes (NG, nasojejunal, duotube, gastrostomy, jejunostomy)
Parenteral Nutrition: 2 types
Peripheral Parenteral Nutrition
Total Parenteral Nutrition (TPN)
Enteral nutrition advantages (7)
- ↓ gut hyperpermability/ translocation
- ↑ gut blood flow
- gut immunity
- ↓ infectious complications
- ↓ mortality
- GB emptying/avoid hepatic chloestasis
Enteral Nutrition Sites
Oral
NGT-nasogastric
G-tube: gastrostomy tube, PEG
J-tube: feeding jejunsotomy
Enteral Nutrition contraindications (5)
& relative contraindications (3)
- bowel obstruction
- peritonitis
- ileus
- massive GI hemorrhage
- ischemic gut
relative contraindications
- pancreatitis
- IBD
- high output fistula
Enteral nutrition complications (4)
- perforation
- aspiration
- dislodgement
- diarrhea
TPN advantages (4)
- ability to provide ‘full’ nutrition without gut
- can tailor the formulation as needed
- inability to use the gut
- inability to get full nutritional needs via enteral feeds
TPN disadvantages (7)
- cholestasis & hepatic dysfunction
- need for vascular access
- INFECTION-line & other
- electrolyte abnormalities
- hyperglycemia
- hyper-triglyceridemia
- costly
Anti-reflux procedure
Nissen fundoplication (laprascopic or open)
Peptic Ulcer Surgery: elective 3 types
Vagotomy & Antrectomy-Bilroth 1
Vagotomy & Pyloroplasty
Highly Selective Vagotomy