Common Drugs Flashcards
Important need-to-know drugs
ACE Inhibitor impact the..
Cardiovascular system
ACE Inhibitors generic names
“pril”: captopril; enalapril; lisinopril
ACE Inhibitors brand names
Capoten; Vasotec; Prinivil
ACE Inhibitors side effects
*cough; hypotension
ACE Inhibitors severe effects
Angioedema; Agranulocytosis
ACE Inhibitors–Nursing Considerations/Vital Assessments
*Obtain BP before administering–hold typically if SBP <90; Change position slowly–especially with elderly to prevent orthostatic hypotension; monitor for decreased WBC count, hyperkalemia as well as liver function, and GFR, creatinine (metabolized by liver–excreted by kidneys)
Beta Blockers impact the…
Cardiovascular system
Beta Blockers generic names
“olol”: atenolol; metoprolol; propranolol
Beta Blockers brand names
Tenormin; Lopressor; Inderal
Beta Blockers side effects
fatigue, weakness
Beta Blockers severe effects
bradycardia; CHF; pulmonary edema
Beta Blockers–Nursing Considerations/Vital Assessments
Obtain BP and HR before administering–hold typically is SBP <90 and HR <60; change position slowly–especially with elderly to prevent orthostatic hypotension; contraindicated in worsening CHF, bradycardia of heart block…use with caution in diabetes, liver disease
Calcium Channel Blockers impact the…
cardiovascular system
Calcium Channel Blockers generic name
Amlodipine; diltiazem; nifedipine; verapamil
Calcium Channel Blockers brand names
Norvasc; Cardizem; Procardia; Calan
Calcium Channel Blockers side effects
peripheral edema
Calcium Chanel Blockers severe effects
cardiac arrhythmias; CHF
Calcium Channel Blockers–Nursing Considerations/Vital Assessments
Change position slowly–especially with elderly to prevent orthostatic hypotension; measure I&O closely and fluid status due to potential for edema; monitor liver and kidney function (metabolized in liver–excreted in kidneys); Obtain BP and HR before administering–hold typically if SBP <90 and HR <60
Vasodilators impact the…
Cardiovascular system
Vasodilators generic names
hydralazine; isosorbide; nitroglycerine
Vasodilators brand names
Apresoline; Isordil; Tridil
Vasodilators side effects
dizziness; headache; hypotension; tachycardia
Vasodilators–Nursing Considerations/Vital Assessments
- Tolerance common and serious problem with long acting nitrates. Nitrates lose their effectiveness if transdermal patches remain on continually. Patches must be taken off at night and then reapplied in the morning.
- Contraindicated if client taking any erectile dysfunction meds as these are a similar nitrate that improves blood circulation to the penis–synergistic effect can cause dramatic hypotension
Blood Pressure Agents
Vasodilators; Calcium Channel Blockers; Ace Inhibitors; Beta Blockers
Cholesterol Binding Agents
Statins
Statins impact the
cardiovascular system
Statins generic names
lovastatin; rosuvastatin; simvastatin; atorvastatin
Statins brand names
Mevacor; crestor; zocor; lipitor
Statins side effects
abdominal cramps; constipation; diarrhea; heartburn; rashes
Statins severe effect
rhabdomyolosis
Statins–Nursing Considerations/Vital Assessments
Give with or without food; Can cause liver injury/damage–watch AST-alk phos, bili levels closely; can cause muscle injury/damage. If CPK elevated DC use
Heart Rhythm Stabilizers
Class III antiarrythmics; digitalis
Class III Arrhythmic meds impact the
cardiovascular system
Class III Arrhythmic generic name
amiodarone
Class III Arrhythmic brand name
Cordorone
Class III Arrhythmic side effects
dizziness; fatigue; malaise; ataxia; bradycardia
Class III Arrhythmic severe effect
pulmonary fibrosis
Class III Arrhythmic meds–Nursing Considerations/Vital Assessments
*Watch for QT prolongation–can lead to VT/VF with IV; assess HR before giving–hold if <60 with IV; Can cause pulmonary toxicity with chronic use–assess for crackles, diminished breath sounds, fatigue, pleuritic chest pain; Assess for neurotoxicity (ataxia, muscle weakness, tingling in fingers/toes, tremors); Assess for signs of thyroid dysfunction (lethargy, weight gain, edema…HYPOTHYROIDISM or tachycardia, weight loss, nervousness–HYPERTHYROIDISM); Monitor liver labs (AST-ALT-bili) and thyroid labs (T3/T4)
Digitalis impacts the
cardiovascular system
Digitalis generic name
digoxin
Digitalis brand name
Lanoxin
Digitalis side effects
fatigue; bradycardia; anorexia; N/V
Digitalis sever effect
arrythmias
Digitalis–Nursing Considerations/Vital Assessments
Apical pulse for 1 minute before giving–hold if <60; increase fall risk for elderly–assess closely; Monitor K+, Mg+, Ca+ levels closely–if these are low more likely to become a digoxin toxic. Elderly more likely; Assess serum levels of digoxin (norm 0.5-2.0); Assess for TOXICITY–abdominal pain, anorexia, N/V, bradycardia, visual changes)
Diuretics
Loop; K+ Sparring; Thiazides
Loop diuretics impact the
cardiovascular system
Loop diuretics generic name
furosemide
Loop diuretics brand name
Lasix
Loop diuretics side effects
dehydration; hypovolemia; hypokalemia; hyponatremia; hypomagnesemia
Loop diuretics–Nursing Considerations/Vital Assessments
Change position slowly–especially with elderly to prevent orthostatic hypotension; Obtain BP before administering–hold typically if SBP <90; Monitor sodium and K+ levels closely as well as GFR and creatinine; Assess for signs of hypokalemia (weakness-fatigue-increased PVC’s on cardiac monitor)
Potassium Sparring Diuretics generic name
spironlactone
Potassium Sparring Diuretics brand name
Aldactone
Potassium Sparring Diuretics side effect
hyperkalemia
Potassium Sparring Diuretics-Nursing Considerations/Vital Assessments
Aldactone and ACE Inhibitors can cause resultant hyperkalemia; If on Aldactone–make sure does not use potassium base salt substitutes or foods rich in K+
Thiazides generic name
hydrochlorothiazide
Thiazides brand name
HCTZ
Thiazides side effect
hypokalemia
Thiazides–Nursing Considerations/Vital Assessments
Monitor BP, I&O, daily weight and for presence of edema; If on DIGOXIN, assess closely for signs of digoxin toxicity since they are at higher risk of developing because of the K+ depleting effects of the diuretic; Monitor K+, Na+, Mg+ and creatinine levels closely
Anticoagulants impact the
blood
Anticoagulants generic names
warfarin; heparin (IV/SQ); Lovenox (SQ)
Anticoagulants brand names
Coumadin (warfarin); Heparin; Lovenox
Warfarin severe side effect
GI bleeding most common
Warfarin–Nursing Considerations/Vital Assessments
Assess for bleeding: tarry black, or maroon stools, nosebleeds, bruising, hematuria; Monitor Hbg, INT (therapeutic range 2-3 for anticoagulation); Excreted by liver–assess AST/ALT
Heparin/Lovenox side effects
anemia; thrombocytopenia
Heparin/Lovenox severe effect
bleeding
Heparin/Lovenox–Nursing Considerations/Vital Assessments
Assess for bleeding: tarry black, or maroon stools, nosebleeds, bruising, hematuria; Administer SQ in abd, NOT proximal to umbilicus; Assess for decreased platelets(heparin induced)
Analgesic classes
narcotics; combo; non-narcotic; NSAIDS
Narcotics impact the
CNS
Narcotics generic names
hydromorphone; morphine; oxycodone; codeine
Narcotics brand name
Dilaudid; MS Contin; Oxycontin; Codeine
Narcotics side effects
confusion; sedation; hypotension; constipation
Narcotics severe effect
respiratory depression
Narcotics–Nursing Considerations/Vital Assessments
Assess BP-HR-R and LOC closely after giving–especially when during its peak; Elderly more senstivie to effects of opioid analgesics and develop SE and respiratory complications more frequently; Assess bowel function closely due to risk of constipation; Tolerance develops with long-term use–will need higher doses to achieve adequate pain relief
Combo pain meds impact
CNS
Combo generic names
oxycodone-acetaminophen; hydrocodone-acetaminophen; codeine-acetaminophen
Combo brand names
Percocet (O/A); Vicodin (H/A); Tylenol #3 (C/A)
Combo pain meds side effects
confusion; sedation; hypotension; constipation
Combo pain meds severe effect
respiratory depression
Combo Pain Meds–Nursing Considerations/Vital Assessments
Assess pain relief to med 1 hour (PEAK) after giving PO; Assess BP-HR-R and LOC closely after giving–especially when drug is peaking; Elderly more sensitive to effects of opioid analgesics and develop SE and respiratory complications more frequently; Assess bowel function closely due to risk of constipation; tolerance develops with long term use–will need higher doses to achieve adequate pain relief.
Non-Narcotic meds impact
CNS
Non-Narcotic generic name
acetaminophen; Aspirin
Non-Narcotic brand names
Tylenol; ASA
Non-Narcotic severe effects
liver failure, toxicity w/ OD or high doses
Non-Narcotic meds–Nursing Considerations/Vital Assessments
Max daily dose is 4000mg; Liver damage can result if reaches this level or is malnourished or abuse ETOH more likely to be toxic; Monitor liver labs (AST-ALT-bili-PT/INR) with Tylenol and Aspirin; Give Aspirin w/ food to minimize risk of ulcer/GI bleed
Non-Steroidal Anti-Inflammatory (NSAIDS) impact
CNS
NSAIDS generic name
ibuprofen; indomethacin; naproxsyn; ketorlac
NSAIDS brand name
Motrin/Advil; Indocin; Aleve; Toradol
NSAIDS side effects
headache; constipation; N/V
NSAIDS severe effect
GI bleeding; hepatitis
NSAIDS–Nursing Considerations/Vital Assessments
Give w/ food to minimize risk of ulcer/Gi Bleeding; Assess for GI bleeding: tarry black, or maroon stools, lightheaded, tachycardia; Elderly are at higher risk to develop GI bleeding; Monitor liver labs (AST-ALT-bili-PT/INR); Assess response to pain med 1-2 hours after giving; Increases bleeding times, be sure to discontinue before surgery. Effects last 24 hours after LAST dose
Anti-anxiety meds impact the
CNS
Anti-anxiety meds generic names
alprazolam; diazepam; lorazepam
Anti-anxiety meds brand name
Xanax; Valium; Ativan
Anti-anxiety meds side effects
dizziness; drowsiness; lethargy
Anti-anxiety meds-Nursing Considerations/Vital Assessments
Assess closely for dizziness, drowsiness with first doses; CNS side effects increase with elderly
Anti-convulsant meds impact the
CNS
Anti-convulsant meds generic names
carbamazepine; gabapentin; levetiracetam; phenytoin
Anti-convulsant meds brand names
Tegretol; Neurontin; Keppra; Dilantin
Anti-convulsant meds side effects
Drowsiness; ataxia; weakness
Anti-convulsant meds–Nursing Considerations/Vital Assessments
Neurontin commonly used for neuropathic pain or chronic pain syndromes
Anti-Depressant meds impact the
CNS
Anti-Depressant meds are also known as
SSRI (selective serotonin reuptake inhibitors)
Anti-Depressant meds generic names
citalopram; fluoxetine; paroxetine
Anti-Depressant meds brand names
Celexa; Prozac; Paxil
Anti-Depressant meds side effects
drowsiness; headache; insomnia; nervousness; tremors
Anti-Depressant meds–Nursing Considerations/Vital Assessments
Require 2 weeks to have physiologic effects with new medications; Assess for increased suicidal tendencies with new therapy
Anti-Parkinson meds impact the
CNS
Anti-Parkinson meds generic name
carbidopa-levodopa
Anti-Parkinson meds brand name
Sinemet
Anti-Parkinson meds side effects
N/V; involuntary movements
Anti-Parkinson meds–Nursing Considerations/Vital Assessments
OK to give with food to minimize GI discomfort; Assess for Parkinson’s effects improving: rigidity, tremors, shuffling gait, drooling
Anti-Psychotic meds impact the
CNS
Anti-Psychotic meds generic names
quetiapine; haloperidol
Anti-Psychotic meds brand names
Seroquel; Haldol
Anti-Psychotic meds side effects
constipation; dry mouth; blurred vision; extra-pyramidal reactions (EPSE)
Anti-Psychotic meds–Nursing Considerations/Vital Assessments
OK to give with food to minimize GI irritation; Assess mental status (mood-orientation-behavior) before and after giving; Monitor for increased restlessness/agitation after first dose–this is a side effect; Monitor for EPSE–there are Parkinson like: difficulty/speaking or swallowing, loss of balance, pill rolling, rigidity, shuffling gait and tremors; Monitor for dystonic reaction: muscle spasms, especially in neck causing head to stay fixed on affected side, weakness of extremities
Gastric Acid Reducers are
Proton Pump Inhibitors (PPI) and Histamine Blockers (H2)
PPI impact the
GI
PPI generic names
pantoprazole; omeprazole
PPI brand names
Protonix; Prilosec
PPI side effect
abdominal pain
PPI–Nursing Considerations/Vital Assessments
May give with or without regards to food; Assess frequently for epigastric/abdominal pain and blood in stool, emesis
H2 impacts the
GI
H2 generic names
cimetadine; famotidine; ranitidine
H2 brand names
Tagamet; Pepcid; Zantec
H2 side effect
confusion
H2 severe effect
Arrythmias
H2–Nursing Considerations/ Vital Assessments
Give with food to prolong effects; Assess frequently for epigastric/abdominal pain and blood in stool, emesis
Anti-Nausea meds impact the
GI
Anti-Nausea meds generic names
ondansetron; prochlorperazine; promethazine
Anti-Nausea meds brand names
Zofran; Compazine; Phenergan
Anti-Nausea meds side effects
headache; constipation; diarrhea; extrapyramidal reactions (compazine)
Anti-Nausea meds–Nursing Considerations/Vital Assessments
May develop