Common breast conditions - teaching Flashcards

1
Q

Functional unit breasts

A
  • Lobules
  • Consists of small alveolar sacs
  • Secretion of milk into ducts
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2
Q

What tethers breast onto chest wall?

A
  • Suspensory ligament of cooper
  • If cancer invades this, causes puckering of skin
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3
Q

Causes of gynaecomastia

A
  • Liver disease
  • Dopamine antagonists
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4
Q

Axillary lymph nodes

A
  • 5 groups
  • Lateral - humeral group, along margin of humerus
  • Anterior - anterior axillary fold
  • Posterior - posterior axillary fold
  • Central - centre of axilla
  • Apical - apex axillax
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5
Q

Triple assessment - 3 parts

A
  1. History and examination
  2. Imaging - if under 35 - USS, older mammogram, MRI if younger and highly suspicious or maybe ruptured implant
  3. Tissue diagnosis - FNA cytology or core biopsy
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6
Q

Why do younger people have US rather than mammogram?

A

In younger women:
* Less fatty tissue
* More fibrous tissue - easier to visualise with USS

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7
Q

Congenital disorders of breast

A
  • Without nipples
  • Accessory nipples along milk line
  • Benign
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8
Q

Mastitis

A
  • Inflammation of breast
  • Presents with painful breasts, discharge, swelling, fever
  • Short history - days-weeks
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9
Q

Cyst vs abscess

A
  • Cyst has absent fever, not erythematous unless infected
  • And usually affects older women
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10
Q

Operations for abscess

A
  • Incision and drainage
  • Hadfields operation - circumareolar incision, open multiple ducts to allow drainage
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11
Q

Duct ectasia?

A
  • Means dilated
  • Presents with discharge - variable colours
  • Benign
  • Smoking is RF
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12
Q

Management duct ectasia

A
  • Smoking cessation
  • Conservative
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13
Q

Breasts cysts

A
  • More likely over 50
  • Soft, fluctuant breast swelling
  • Otherwise systemically well
  • Should drain them as chance of malignant transformation
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14
Q

Intraductal papilloma

A
  • Outprojection of duct- benign tumour
  • Can shear off and cause bleeding = bloody discharge
    *
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15
Q

Fat necrosis

A
  • Following trauma to breasts - firm lumps or lumpy breasts
  • Reassure
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16
Q

Fibroadenoma

A
  • Breast mouse, very mobile in all planes
  • Young female 18-25
  • Firm
  • Can become quite large - if >4cm or symptomatic have lumpectomy or quadrantectomy (if small breasts with large lump)
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17
Q

Risk with fibroadenoma

A
  • No risk of malignant transformation to breast cancer
18
Q

Lobular carcinoma vs ductal

A
  • Lobular more likely to spread distally
19
Q

Arterial supply to breast

A

Medial:
* Internal mammary artery

Lateral:
* Lateral thoracic and thoracoacromial (axillary artery origin)
* Lateral mammary branches (intercostal arteries off aorta)
* Mammary branch (anterior intercostal artery)

20
Q

Lymphatic drainage breast

A
  • Axillary
  • Parasternal
  • Posterior intercostal

Skin –> axillary, inferior deep cervical and infraclavicular
Nipple and areola –> subareolar lymphatic plexus

21
Q

Venous drainage breast

A

Correspond to arteries
Drain into axillary and internal thoracic veins

22
Q

Factors deciding mastectomy vs WLE

A

Mastectomy if:
* Multifocal
* Central
* Large lesion in small breast
* DCIS >4cm
* Patient choice

23
Q

Nottingham prognostic index

A

Tumour size x 0.2 + lymph node score + grade score

24
Q

Lymph node score

A
  • 0 nodes = 1
  • 1-3 nodes =2
  • > 3 nodes = 3
25
Organism involved in mastitis
* Staphylococcus aureus
26
Tender lump around areola and green/other coloured dishcarge at age 49
Mammary duct ectasia
27
Irregular lump following trauma
* Fat necrosis
28
Irregular lump, 41 year old, fixed
Breast cancer
29
Management of a symptomatic fibroadenoma or if it's more than 3cm
* Surgical excision
30
Bloody discharge from nipple in a younger person
Intraductal papilloma
31
Management of breast cyst
* Aspiration due to small risk of progression to cancer * Esp in younger patients
32
Discharge from multiple ducts with nipple inversion, 53 year old
* Duct ectasia
33
Most common breast cancer
* Ductal carcinoma in situ * Then invasive ductal carcinoma
34
Greatest risk of pathological # from cancer
* Peritrochanteric lesion from breast cancer - lytic lesions in hip * Not prostate as causes sclerotic
35
Soft mushy swelling between breasts that has been present for whole life
Lipoma - in sternal area
36
Erythematous rash originating from nipple and spreading to areola and surrounding tissue
Pagets disease of nipple Not eczema as this usually spares nipple
37
Side effects of anastrozole
* Osteoporosis * VTE * Endometrial cancer * Vaginal bleeding
38
Surveillance for BRCA1 and TP53 mutation in young female
Annual MRI
39
Cancer most likely to spread to opposite breast
Invasive lobular cancer
40
Sign of cyst on mammogram
Halo sign