Common and chemical agents use in microbial control Flashcards

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1
Q

it hydrolyzes and coagulates proteins

A

acid and alkali solutions

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2
Q

first widely used antiseptic and disinfectant, it is effective even in the presence of organics and it remains active for a long period when applied on surfaces

A

Phenol and phenolic compounds (tuberculocidal)

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3
Q

examples of Phenol and phenolic compounds

A

cresols, xylenols, lysol

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4
Q

is is used both as an antispetic and disinfectant- bactericidal and fungicidal

A

Alcohol (non-sporicidal)

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5
Q

most ideal to denature microorganisms

A

70% alcohol

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6
Q

disadvantage of alcohol

A

it has a poor activity against nonenveloped viruses

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7
Q

it destroys microorganisms by oxidation mechanism

A

Halogen

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8
Q

effective antiseptics

A

tincture of iodine and iodophor

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9
Q

contains chloride and used to disinfect drinking water

A

Halozone (parasulfone dichloroaminobenzoic acid)

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10
Q

effective bleach

A

1:10 dilution of sodium hypochlorite (NaOCL)

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11
Q

is more stable than iodine in its pure form and is a combination of iodine and neutral polymer (detergent)

A

Iodophor

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12
Q

Antibacterial effect of iodophor

A

oxidative effects of molecular iodine and hypoiodic acid

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13
Q

degrades microbial cell walls, cytoplasm, denatures enzymes and coagulates chromosomal material

A

Free iodine

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14
Q

for handwashing, surgical hand scrub, and preoperative skin preparation

A

5-10% povidine-iodine

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15
Q

is used in the form of hypochlorite

A

chlorine

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16
Q

antibacterial effect of chlorine

A

oxidative effects of hypochlorous acid (formed when chloride ions are dissolved in water)

17
Q

recommended by CDC’s for cleaning blood spills

A

1:10 dilution of 5.25% solution

18
Q

contact time of chlorine

A
2 minutes ( longer in the presence of organic material)
10-30 minutes = mycobacteria
19
Q

are both antiseptic and disinfectant

A

iodophor and alcohol

20
Q

tincture of iodine contains

A

2% iodine and 70% alcohol

21
Q

is the most common form of skin disinfection before drawing blood for culture or surgery

A

70% alcohol followed by an iodophor

22
Q

it destroys microorganisms by inactivation and precipitation of cell proteins

A

salts of heavy metals

23
Q

eye drop solution

A

AgNO3

24
Q

algicide

A

CuSO4

25
Q

antiseptic

A

mercuric chloride

26
Q

2 components of QUATS

A

detergent and phenolics

27
Q

it is used as surface-active agents

A

detergent (nontuberculocidal and nonsporicidal)

28
Q

antibacterial effect of detergent

A

it disrupts cell membrane, resulting in leakage of cell contents

29
Q

use of detergent

A

lab bench tops and floors

30
Q

resistant to quats

A

P. aeruginosa

31
Q

are molecules of phenol that have been substituted by halogens and are stable, biodegradable, and active in the presence of organic material

A

phenolics (nonsporicidal)

32
Q

antibacterial effect of phenolics

A

disruption of cell cell walls

33
Q

use of phenolics

A

hospital floors and surroundings

34
Q

antibacterial effect of aldehydes

A

inactivation of proteins and nucleic acids

35
Q

use of aldehydes

A

sterilize medical instruments

36
Q

example of aldehydes

A

aldehyde fomaldehyde (8%) and glutaraldehyde (2%)

37
Q

it is generally used as formalin

A

formaldehyde (37 aqeuous solution or HCHO gas)

38
Q

how many percent of HCHO

A

3-8% with a contact time of 30 minutes (mycobacteria)

39
Q

use of formaldehyde

A

to sterilize HEPA filters in biological safety cabinets (formaldehyde vapor