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Immunology > Collagen Galore > Flashcards

Collagen Galore Flashcards

1
Q

Type I Collagen

A

Most common, high tensile strength
Defective in OI

Bone
Skin
Tendon
Dentin
Fascia
Cornea
Late wound repair
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2
Q

Type II Collagen

A

CarTWOlage (including hyaline)
Vitreous body
Nucleus Pulposus

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3
Q

Type III Collagen

A

Pliable
Defective in Ehlers-Danlos

Reticulin 
Skin 
Blood vessels
Uterus
Fetal tissue
Granulation tissue
KELOID
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4
Q

Type IV Collagen

A

BM
Basal lamina

Defective in Alport syndrome

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5
Q

Collagenase

A

Zinc Cofactor

Removes type III collagen in granulation tissue for deposition of type I collagen

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6
Q

Lysyl oxidase

A

Cross links lysine and hydroxylysine of tropocollagen extracellularly

Requires copper cofactor

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Immunology (4 decks)

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