Collagen Flashcards
1
Q
Type of protein?
A
Fibrous
2
Q
Function?
A
High tensile strength
3
Q
Describe its Pri struct’
A
Each collage polypeptide
- alpha chain of 1000 aa by strong covalent peptide bonds;
- alpha chain the repeat of tripe pride seq glycine-X-Y;
- x proline; y hydroxyproline, hydroxylysine, lysine
4
Q
Describe quaternary struct’
A
Three helical alpha-chains form tropocollagen;
Inter-chain H bonds and covalent cross-bridge
5
Q
Why glycine at every third position?
A
Smallest;
Coil more tightly
6
Q
Why proline in second position?
A
Gives alpha chain link to turn at every third residue
7
Q
Why collagen acts as structural support?
A
Large molecular size of tropocollagen molecule;
Insoluble in water
