Cold acclimation Flashcards

1
Q

define adaptation

A
  • changes that reduce the physiological strain produced by stressful components
  • changes can be phenotypical or genotypical
  • Does not require specification of the climatic component of the total environment
  • no distinct terms relating to genotypic adaptations
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2
Q

Define habituation

A
  • desensitization or dampening of the normal response to a stressor
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3
Q

What metabolic, peripheral blood flow and insulator changes are associated with cold acclimation

A
  • decrease in metabolic rate (by ~20%)
  • reduced peripheral blood flow
  • little effect on insulation; maybe an increase in the gradient between core and skin temp
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4
Q

What are the 3 categories of adaptations we can see in the cold

A
  • metabolic adaptations
  • hypothermic adaptations
  • insulative adaptations
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5
Q

In chronic cold stress when there is no body heat loss what is the body’s response

A
  • Cold habituation: Blunted shivering/cutaneous vasoconstriction
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6
Q

In chronic cold stress when there is body heat loss and metabolic heat is sufficient to defend body temp what is the body’s response

A

Metabolic acclimation: Enhanced shivering thermogenesis/NST

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7
Q

In chronic cold stress when there is body heat loss and metabolic heat is not sufficient to defend body temp what is the body’s response

A
  • insulative acclimation: Enhanced vasoconstriction, improved muscle blood flow
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8
Q

What metabolic adaptions can be seen in humans

A
  • Results are varied: but
  • increased BMR
  • more intense shivering/elevated NST
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9
Q

What metabolic adaptations have been shown in mice and rats

A
  • mice: increased energy expenditure in mice; varied by strain
  • Rats: increased sensitivity to NE/greater production of NE
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10
Q

Describe the BAT/NST experiment in the knock-out mice, what were the results

A
  • UCP-1 KO mice shown a decrease in NST and no response to NE when cold adapted
  • Mice with UCP-1 showed an increase in NST
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11
Q

How does the amount of BAT change based on the climate someone lives in

A
  • Increase BAT in cold climate
  • ex. homeless alcoholic vs average person
  • possible confounding factors??
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12
Q

What adaptations do the Ainu people have

A
  • increased metabolic response in the cold

- more FFA oxidation

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13
Q

Looking at BAT around the body, what type of adaptations?

A
  • post-acclimation there is a large difference in BAT NST when exposed to cold
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14
Q

How does exercise affect these metabolic adaptations?

A
  • low impact on shivering and metabolism during exercise

- meaning training in the cold has minimal-no effect

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15
Q

What types of hypothermic adaptations do we see in cold acclimated individuals

A
  • greater fall in core temperature
  • skin temperature is maintained or decreased
  • redistribution of circulation to periphery to give warmer skin ie maintain a colder core
  • reduced NE response (habituation, not acclimation)
  • maintained or decreased metabolic rates
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16
Q

When looking at the Ama divers vs control divers, what can be concluded about their shivering

A
  • start shivering at a lower core temperature

- Therefore cold acclimated

17
Q

what insulative changes can be expected in response to cold acclimation

A
  • more vasoconstriction or an improved countercurrent heat exchange
  • therefore lower skin temperature
18
Q

How does the maximal tissue insulation/subcutaneous body fat of the ama divers compare to the regular population

A
  • greater max tissue insulation/unit of subcutaneous body fat
  • cold adapted
19
Q

How does maximal insulation change with exercise

A
  • maximal insulation decreases due to perfusion of muscle
20
Q

Does cold acclimation improve exercise performance in the cold

A
  • no; after insulative acclimation cycling performance was equally impaired during cold exposure as it was prior to acclimation
21
Q

Does acclimation to extreme cold have an effect on exercise performance

A
  • in dynamic exercise neuromuscular functions may adapt to repeated whole body cryotherapy (ex. drop test)