Coiled Coil Structures Flashcards
1
Q
Describe the gross geometry of a coiled coil.
A
Each turn contributes 6.5 A of length.
Helices tilted 20 degress towards each other.
Diameter is 20 degrees.
2
Q
What is the pitch?
A
Superhelical repeat.
In a dimeric coiled coil = 140 A.
As number of helices increases so does length of pitch.
3
Q
How did the salt bridges become altered in GCN4pI when changed to tetramer?
A
Outside helical residues move closer together as structure gets larger.
Gā>B and Cā>E salt bridges.
