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632 Advanced Anesthesia Health Assessment > Cognitive Assessment > Flashcards

Cognitive Assessment Flashcards

1
Q

Where does Serotonin arise from in the CNS?

A
  • Raphe nuclei make Serotonin
    (Brainstem)
  • Projects extensively to all levels of the CNS
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2
Q

What does Serotonin help regulate ?

A
  • Mood
  • Arousal
  • Cognition
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3
Q

Where does Norepinephrine arise from in the CNS?

A
  • From the Locus coeruleus (brainstem)

- Extends to areas of the CNS including the spinal cord, cerebellum, thalamus, & cerebral cortex

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4
Q

What does Norepinephrine regulate

A
  • Mood
  • Arousal
  • Attention
  • Cognition
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5
Q

Where does Dopamine arise from in the CNS?

A

From the Substantia nigra & the ventral tegmental area (brainstem & midbrain)

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6
Q

What does Dopamine regulate?

A
  • Mood
  • Arousal
  • Cognition
  • Motor control
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7
Q

Where does Acetylcholine arise from in the CNS?

A
  • From the Basal forebrain & brainstem (cerebral cortex, including the hippocampus)
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8
Q

What does Acetylcholine (ACh) regulate?

A
  • Sleep
  • Arousal
  • Attention
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9
Q

Depressive symptoms arise with what chemical imbalance?

A
  • Low levels of Serotonin, Norepinephrine, & Dopamine
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10
Q

Anxiety symptoms arise with what chemical imbalance?

A
  • Low levels of Serotonin

- High levels of Norepinephrine

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11
Q

Psychosis & Mania symptoms arise with what chemical imbalance?

A
  • High levels of Dopamine

- Low levels of Serotonin

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12
Q

Dementia symptoms arise with what chemical imbalance?

A
  • Low levels of Acetylcholine
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13
Q

What is classified as a mental disorder

A
  • Any condition or syndrome with clinical manifestations characterized by Significant impairment in:
    • Cognition, Emotion regulation, & Behavior
      Leading to significant distress &/or disability in social, occupational, or other important activities of daily life. “DSM-5”
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14
Q

What are the 4 most common or concerning symptoms in a cognitive assessment?

A
  1. Anxiety/ excessive worrying
  2. Depressed mood
  3. Memory problems
  4. Medically unexplained symptoms
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15
Q

6 Common risk factors for Anxiety

A
  1. Family Hx
  2. Personal Hx or mood disorder
  3. Childhood stressful life events or trauma
  4. Female
  5. Chronic medical illness
  6. Behavioral inhibition
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16
Q

Generalized Anxiety Disorder

A
  • Excessive worrying predominates over a 4 week period
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17
Q

Social Anxiety Disorder

A
  • Avoidance due to unreasonable fear of situations or activities that could lead to embarrassment, marked by anticipatory anxiety in social situations
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18
Q

Obsessive Compulsive Disorder

A
  • Characterized by intrusive thoughts & ritualistic behaviors
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19
Q

Panic Disorder

A
  • Often presents with recurrent sudden episodes/ spells/ attacks of intense fear or discomfort that are unexpected or w/ intervening periods of living in fear or worrying of having another attack or facing the consequences of the attack
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20
Q

Post Traumatic Stress Disorder

A
  • Characterized by re-experiencing, avoidance, persistent negative alterations in cognition & mood, & alterations in arousal & reactivity
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21
Q

Other potential causes that can mimic Anxiety

A
  1. OTC & prescription medications
  2. Illicit substances/ caffeine/ alcohol
  3. Mood disorders
  4. Hyperthyroidism
  5. Cardiopulmonary disorders
  6. TBI
  7. Untreated pain in PACU
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22
Q

5 Risk factors for Depression

A
  1. Personal Hx of a depressive episode**
  2. Family Hx of 1st degree family members w/ depression
  3. Personal Hx of recent stressful life events or significant childhood adversity
  4. Chronic/ disabling medical illness
  5. Female
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23
Q

Premenstrual Dysphoric Disorder (PMDD)

A
  • Depressive symptoms worsen in sync w/ a female’s menstrual cycle
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24
Q

Major Depressive Disorder (MDD)

A
  • At least 2 weeks of depressed/irritable mood, with at least 4 of the following:
    • Anhedonia
    • Insomnia/hypersonic
    • Decreased self-esteem
    • Low energy
    • Poor concentration/indecision
    • Changes in appetite
    • Feeling slowed or restless
    • Thoughts of death/ suicide
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25
Persistent Depressive Disorder (PDD)
- Depressive/ irritable mood lasting for at least 2 years & > 2+ of the MDD symptoms
26
MDD & PDD are frequently comorbid with what 3 findings
1. Anxiety 2. Personality disorders 3. Substance use
27
What 6 other conditions mimic Depression
1. Alcohol/drug use 2. Parkinson disease 3. TBI 4. Recent MI 5. Stroke 6. Hypothyroidism
28
10 Key components of the mental status examination
1. Appearance/ behavior (LOC) 2. Posture/ motor behavior 3. Grooming 4. Affect (appropriate/flat) 5. Manner (detached/anxious) 6. Speech/language 7. Mood 8. Thoughts & perception (organized/hallucinations) 9. Insight/judgement 10. Cognition
29
Incoherence
- Speech that is incomprehensible & illogical - Lack of meaningful connections - Abrupt changes in topic - Disordered grammar or word use - Seen in severe psychotic disturbances: schizophrenia
30
Neologisms
- Invented or distorted words | - Seen in: Schizophrenia, psychotic disorders, & aphasia
31
Blocking
- Disordered thought process with sudden interruption of speech midsentence - Can occur in normal people - Seen in schizophrenia
32
Clanging
- Disordered thought process where choice of words is based on sound rather than meaning (rhyming) - Seen in Schizophrenia & manic episodes
33
Flight of Ideas
- Disordered thought process that has continuous flow of accelerated speech with abrupt changes from one topic to the next - Changes are based on associations, play on words, or distracting stimuli - Ideas are not well connected - Seen in Manic episodes
34
Broca aphasia
- Expressive aphasia - Preserved comprehension w/ slow, non-fluent speech (Can understand what you are saying but the words come out gibberish)
35
Wernicke aphasia
- Receptive aphasia | - Impaired comprehension with fluent speech
36
Paranoia affect findings during mental assessment
- Anger, hostility, suspiciousness, or evasiveness
37
Mania affect findings during mental assessment
- Elation & euphoria
38
Schizophrenia affect findings during mental assessment
- flat affect & remoteness
39
Dementia, anxiety, & depression affect findings during mental assessment
- Dulled affect w/ detachment & indifference & apathy
40
What are 3 conditions that can cause hallucinations assessed during your affect assessment for mental health
1. Schizophrenia 2. Alcohol withdrawal 3. Systemic toxicity
41
Cognition definition
- The mental processes involved in gaining knowledge and comprehension Includes: Orientation, Attention, & Memory (recent, remote, new learning) - as well as higher cognitive functions: information & vocabulary, calculation, abstract thinking, constructional ability
42
What cognitive function is usually unaffected by mental disorders?
Vocabulary
43
Amnestic disorder key findings
- Impair memory or new learning ability, reduce social or occupational functioning & lacks the global features of delirium or dementia (recent memory is impaired, but remote is intact)
44
Poor constructional ability suggests?
- Dementia or parietal lobe damage
45
Mental illness increases risks for what 5 things
1. Chronic medical conditions 2. Decreased life expectancy 3. Disability 4. Substance abuse 5. Suicide
46
5 high risk patients for depression
1. Young females who are single, divorced or separated 2. Seriously or chronically ill 3. Bereaved 4. Hx of other psychiatric disorders including substance abuse 5. Personal or family Hx of depression
47
Definition of Dementia
- An acquired condition that is characterized by decline in at least two cognitive domains (e.g., loss of memory, attention, language, or Visuospatial or executive funct.) that is severe enough to affect social or occupational functioning
48
What are 6 Major Dementia syndromes
1. Alzheimer’s disease 2. Vascular dementia 3. Frontotemporal dementia 4. Lewy body dementia 5. Parkinson disease w/ dementia 6. Dementia of mixed etiology
49
What is the best known screening test for dementia?
Mini-Mental State Examination
50
What is the most commonly performed screening tests?
1. The Mini-COG - 3 minute test w/ 91% sensitivity & 86% specificity 2. Montreal Cognitive Assessment - 10 minute test comparable to mini-cog - 91% sensitivity & 81% specificity (not as good at diagnosing, rather who needs further help or not)
51
Age- related cognitive decline
- Mild forgetfulness, difficulty remembering names, & mildly reduced concentration - Sporadic symptoms & do not affect daily function
52
Mild cognitive impairment
- Daily function is preserved, but evidence of MODEST cognitive decline in 1 or more cognitive domains based on objective tasks (orientation, memory, vocabulary, calculation, abstract thinking) - Alertness & Attention are preserved (unlike delirium) - Can progress to AD
53
Alzheimer’s Disease**
- affects 10% over the age 65 (2/3 women) - Memory difficulties take the form of: - Repeating questions - Loosing objects - Confusion when performing tasks (shopping)
54
Alzheimer’s Disease risk factors**
- Advancing age - Family Hx - Gene mutation Apolipoprotein - risk doubles w/ one mutation - risk is 5x’s w/ 2
55
Alzheimer’s Disease late stage signs & symptoms **
- Impaired judgement & Disorientation - Progresses to aphasia, apraxia, left-right confusion & ultimately dependence of instrumental activities of daily living - Psychosis & agitation may also occur
56
Vascular Dementia
- Vascular risk factors or cerebrovascular disease assoc. w/ cognitive impairment - Stepwise decline (especially in executive function) correlating with the onset of a cerebrovascular event - Can have gait changes & focal findings
57
Lewy Body Dementia
- Evidence of Parkinsonism - Visual hallucinations, delusions, & gait disorder - Extrapyramidal symptoms, fluctuating mental status, & sensitivity to antipsychotic medications
58
Frontotemporal dementia
- Prominent behavioral or language disorders - Personality changes including impulsivity, aggression, & apathy - Excessive eating & drinking - Preservation of memory & visual-spatial
59
Delirium
- An acute confusional state marked by sudden onset, fluctuating course, inattention, & at times, changing levels of consciousness
60
3 Risk factors for Delirium
1. Hospitalized general medical patients 2. Major elective surgery 3. ICU admissions
61
What is a positive CAM
- positive screening for delirium that includes the presence of acute change in mental status/ fluctuating course (1) w/ inattention (2) plus either disorganized thinking (3) or abnormal level of consciousness (4) - 1 & 2 have to be present plus either 3 or 4 (Score highest = 7)
62
Somatic symptom disorder
- Excessive & disproportionate thoughts, feelings, & behaviors related to those symptoms - somatic symptoms are either very distressing or results in significant disruption of functioning
63
Illness anxiety disorder (somatic)
- Preoccupation with having or acquiring a serious illness where somatic symptoms, if present are only mild in intensity
64
Fictitious disorder (somatic)
- Falsification of physical/psychological signs or symptoms, or induction of injury or disease, assoc. w/ identified deception
65
Body dysmorphic disorder (somatic)
- Preoccupation w/ 1 or more perceived defects or flaws in physical appearance that are not observable or appear only slight to others
66
Dissociative disorder (somatic)
- Disruption of &/or discontinuity in the normal integration of consciousness, memory, identity, emotion, perception, body representation, motor control, & behavior

632 Advanced Anesthesia Health Assessment (12 decks)

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