Cognition 2 Flashcards by Rudy McLean

SSRI - drugs, action, side effects, nursing interventions?

Drugs: Sertraline
Action: Block reuptake of serotonin in presynaptic nerve terminals
Side effects: Nausea, dry mouth, insomnia, somnolence, headache, nervousness, anxiety, weight gain, GI disturbances, dizziness, fatigue, sexual dysfunction
Nursing interventions: Safer, less sedation 70% experience sexual dysfunction. Serotonin syndrome - confusion, anxiety, restlessness, hypertension, tremors, sweating, hyperpyrexia, ataxia - DC SSRI, supportive care.

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Atypical (antidepressant) - Action, side effects, nursing interventions?

Action: anxiety, neuropathy
Side effects: Insomnia, nausea, dry mouth, constipation, > BP, > HR, somnolence, sweating, agitation, headache, blurred vision, tremor, > appetite, sexual dysfunction.
Nursing interventions: Bupropion lowers seizure threshold.

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Tricyclic (TCAs - antidepressant) action, side effects, nursing interventions?

Action: Inhibit reuptake of neurotransmitters into presynaptic nerve terminals.
Side effects: Drowsiness, sedation, dizziness, orthostatic hypotension, dry mouth, constipation, urinary retention, blurred vision, sexual dysfunction.
Nursing interventions: Give at bedtime due to sedation.

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MAOIs - Action, side effects, nursing interventions?

Action: Inhibit MAO enzyme activity inside presynaptic nerve terminals.
Side effects: Insomnia, orthostatic hypotension, headache, diarrhea.
Nursing interventions: Limit foods high in tyramines (aged food/drink).

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Sertraline (zoloft) classification?

SSRI antidepressant

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Sertraline (zoloft) contraindications?

Antidepressant - SSRI

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Sertraline (zoloft) uses/action?

Uses: major depression, OCD, panic disorder, social anxiety disorder, anxiety, PTSD.

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Sertraline (zoloft) interactions?

MAOIs
caution w/ all CNS central acting drugs
St. Johns wort
Grapefruit

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Sertraline (zoloft) side effects?

Agitation
Insomnia
Headache
dizziness
somnolence
fatigue
male sexual dysfunction
N&V
Diarrhea
Constipation
Suicidal ideation
Seizure

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Sertraline (zoloft) nursing interventions?

Monitor closely for suicide risk, worsening depression
Monitor older adults to F & E imbalances
Monitor pts. w/ history of seizure disorder closely.
Report diarrhea, nausea, dyspepsia, insomnia, drowsiness, dizziness, persistent headache to HCP.
Report emergence of agitation, irritability, hostility, aggression or mania.

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Aripiprazole (Abilify) classification?

Atypical antipsychotic; dopamine system stabilizer

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Aripiprazole (ability) contraindications?

Dementia related to psychosis
suicidal ideation
NMS, severe neutropenia

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Aripiprazole (abilify) uses?

Bipolar mood disorder

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Aripiprazole (abilify) interactions?

Phenytoin
Fluoxetine
Paroxetine
Alcohol
Tramadol
St. John’s wort
High fat meals delay peak plasma levels

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Aripiprazole (abilify) side effects?

Headache
Anxiety
Insomnia
Light-headedness
Somnolence
Akathisia
Agitation
Headache
N&V
Constipation

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Aripiprazole (abilify) nursing interventions?

Monitor for suicidal ideation or worsening depression
Monitor CV status - hypotension
Monitor for S/S of infection
Monitor temperature, dehydration
Monitor for NMS
Elevated blood glucose
Lab tests: hct/hgb, glucose, CPK, myoglobinuria

Lurasidone (latuda) classification?

Atypical antipsychotic

Lurasidone (latuda) contraindications?

Psychosis
Suicidal ideation
neutropenia or leukopenia
NMS

Lurasidone (latuda) uses/action?

Uses: Bipolar disorder; schizophrenia
Action: Central dopamine & Serotonin receptor antagonism

Lurasidone (latuda) interactions?

Erythromycin
Fluconazole
Rifampin
Grapefruit juice
St. John’s wort

Lurasidone (latuda) side effects?

Akathisia
Parkinsonism
Somnolence
Nausea

Lurasidone (latuda) nursing interventions?

Assess for suicidal ideation
Safety - orthostatic hypotension: initial, > dose
Neutropenia - fever, infection
Weigh pt - weight gain
Elevated blood pressure
NMS
Lab tests - glucose, lipids, LFTs, CBC

Typical-phenothiazines - Action, side effects, nursing interventions?

Action: Block dopamine & serotonin from receptors; decrease excitability
Side effects: Sedation, drowsiness, dizziness, EPS, constipation, photosensitivity, orthostatic hypotension, urinary retention.
Nursing interventions: anti-cholinergic effects, sexual dysfunction, NMS - high fever, tachycardia, incontinence, confusion.

Typical-nonphenothiazines - Drugs, action, side effects, nursing interventions?

Drugs: Haloperidol
Action: Block dopamine receptors
Side effects: Sedation, transient drowsiness, EPS, tremor, orthostatic hypotension
Nursing interventions: less sedation, fewer EPS, no advantage over phenothiazines.

Atypical (antipsychotic) - Drugs, action, side effects, nursing interventions?

Drugs: Aripiprazole, lurasidone, risperidone Action: Action unknown, block different receptors Side effects: Tachycardia, fever, sedation, dizziness, headache, anxiety, nervousness, hostility, insomnia, nausea, dry mouth, vomiting, constipation, EPS. Nursing interventions: Fewer EPS, > Wt gain, diabetes, hypertriglyceridemia, CVA, mortality

Haloperidol (haldol) classification?

Atypical antipsychotic

Haloperidol (haldol) contraindications?

Parkinson's disease seizures CNS depression alcoholism mental depression NMS

Haloperidol (haldol) uses/action?

Uses: psychotic disorders, tourett's syndrome, agitation in acute/chronic psychoses, severe behavioral problems w/ children, hostility Action: Blocks postsynaptic dopamine receptors in limbic system in brain

Haloperidol (haldol) ineractions?

CNS depressants opiates alcohol anticoagulants anticholinergics methyldopa

Haloperidol (haldol) side effects?

Extrapyramidal symptoms, tardive dyskinesia, photosensitivity

Haloperidol (haldol) nursing interventions?

Monitor mental status, NMS, EPS, Parkinsonism, exacerbation of seizures, depression. Lab work: WBC, LFT no alcohol, driving Oral hygiene (dry mouth), > fluids Give with full glass of water, food or milk.

Risperidone (risperdal) classification?

Atypical antipsychotic

Risperidone (risperdal) contraindications?

Elderly dementia - psychosis NMS CNS depression head trauma

Risperidone (risperdol) uses/action?

Schizophrenia bipolar disorder irritability w/ autism

Risperidone (risperdol) interactions?

Antihypertensives Antiparkinson

Risperidone (risperdol) side effects?

Fatigue sedation drowsiness headache insomnia agitation EPS dry mouth vomiting Diarrhea constipation weight gain cough

Risperidone (risperdol) nursing interventions?

Monitor diabetic for loss of glucose control Monitor CV status, neuro status, orthostatic hypotension, seizure risk Assess cognitive motor impairment & environmental hazards No driving until response known No alcohol