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Pharm 2 Exam 1 > Cognition 2 > Flashcards

Cognition 2 Flashcards

1
Q

SSRI - drugs, action, side effects, nursing interventions?

A

Drugs: Sertraline
Action: Block reuptake of serotonin in presynaptic nerve terminals
Side effects: Nausea, dry mouth, insomnia, somnolence, headache, nervousness, anxiety, weight gain, GI disturbances, dizziness, fatigue, sexual dysfunction
Nursing interventions: Safer, less sedation 70% experience sexual dysfunction. Serotonin syndrome - confusion, anxiety, restlessness, hypertension, tremors, sweating, hyperpyrexia, ataxia - DC SSRI, supportive care.

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2
Q

Atypical (antidepressant) - Action, side effects, nursing interventions?

A

Action: anxiety, neuropathy
Side effects: Insomnia, nausea, dry mouth, constipation, > BP, > HR, somnolence, sweating, agitation, headache, blurred vision, tremor, > appetite, sexual dysfunction.
Nursing interventions: Bupropion lowers seizure threshold.

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3
Q

Tricyclic (TCAs - antidepressant) action, side effects, nursing interventions?

A

Action: Inhibit reuptake of neurotransmitters into presynaptic nerve terminals.
Side effects: Drowsiness, sedation, dizziness, orthostatic hypotension, dry mouth, constipation, urinary retention, blurred vision, sexual dysfunction.
Nursing interventions: Give at bedtime due to sedation.

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4
Q

MAOIs - Action, side effects, nursing interventions?

A

Action: Inhibit MAO enzyme activity inside presynaptic nerve terminals.
Side effects: Insomnia, orthostatic hypotension, headache, diarrhea.
Nursing interventions: Limit foods high in tyramines (aged food/drink).

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5
Q

Sertraline (zoloft) classification?

A

SSRI antidepressant

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6
Q

Sertraline (zoloft) contraindications?

A

Antidepressant - SSRI

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7
Q

Sertraline (zoloft) uses/action?

A

Uses: major depression, OCD, panic disorder, social anxiety disorder, anxiety, PTSD.

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8
Q

Sertraline (zoloft) interactions?

A

MAOIs
caution w/ all CNS central acting drugs
St. Johns wort
Grapefruit

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9
Q

Sertraline (zoloft) side effects?

A

Agitation
Insomnia
Headache
dizziness
somnolence
fatigue
male sexual dysfunction
N&V
Diarrhea
Constipation
Suicidal ideation
Seizure

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10
Q

Sertraline (zoloft) nursing interventions?

A

Monitor closely for suicide risk, worsening depression
Monitor older adults to F & E imbalances
Monitor pts. w/ history of seizure disorder closely.
Report diarrhea, nausea, dyspepsia, insomnia, drowsiness, dizziness, persistent headache to HCP.
Report emergence of agitation, irritability, hostility, aggression or mania.

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11
Q

Aripiprazole (Abilify) classification?

A

Atypical antipsychotic; dopamine system stabilizer

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12
Q

Aripiprazole (ability) contraindications?

A

Dementia related to psychosis
suicidal ideation
NMS, severe neutropenia

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13
Q

Aripiprazole (abilify) uses?

A

Bipolar mood disorder

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14
Q

Aripiprazole (abilify) interactions?

A

Phenytoin
Fluoxetine
Paroxetine
Alcohol
Tramadol
St. John’s wort
High fat meals delay peak plasma levels

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15
Q

Aripiprazole (abilify) side effects?

A

Headache
Anxiety
Insomnia
Light-headedness
Somnolence
Akathisia
Agitation
Headache
N&V
Constipation

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16
Q

Aripiprazole (abilify) nursing interventions?

A

Monitor for suicidal ideation or worsening depression
Monitor CV status - hypotension
Monitor for S/S of infection
Monitor temperature, dehydration
Monitor for NMS
Elevated blood glucose
Lab tests: hct/hgb, glucose, CPK, myoglobinuria

17
Q

Lurasidone (latuda) classification?

A

Atypical antipsychotic

18
Q

Lurasidone (latuda) contraindications?

A

Psychosis
Suicidal ideation
neutropenia or leukopenia
NMS

19
Q

Lurasidone (latuda) uses/action?

A

Uses: Bipolar disorder; schizophrenia
Action: Central dopamine & Serotonin receptor antagonism

20
Q

Lurasidone (latuda) interactions?

A

Erythromycin
Fluconazole
Rifampin
Grapefruit juice
St. John’s wort

21
Q

Lurasidone (latuda) side effects?

A

Akathisia
Parkinsonism
Somnolence
Nausea

22
Q

Lurasidone (latuda) nursing interventions?

A

Assess for suicidal ideation
Safety - orthostatic hypotension: initial, > dose
Neutropenia - fever, infection
Weigh pt - weight gain
Elevated blood pressure
NMS
Lab tests - glucose, lipids, LFTs, CBC

23
Q

Typical-phenothiazines - Action, side effects, nursing interventions?

A

Action: Block dopamine & serotonin from receptors; decrease excitability
Side effects: Sedation, drowsiness, dizziness, EPS, constipation, photosensitivity, orthostatic hypotension, urinary retention.
Nursing interventions: anti-cholinergic effects, sexual dysfunction, NMS - high fever, tachycardia, incontinence, confusion.

24
Q

Typical-nonphenothiazines - Drugs, action, side effects, nursing interventions?

A

Drugs: Haloperidol
Action: Block dopamine receptors
Side effects: Sedation, transient drowsiness, EPS, tremor, orthostatic hypotension
Nursing interventions: less sedation, fewer EPS, no advantage over phenothiazines.

25
Q

Atypical (antipsychotic) - Drugs, action, side effects, nursing interventions?

A

Drugs: Aripiprazole, lurasidone, risperidone
Action: Action unknown, block different receptors
Side effects: Tachycardia, fever, sedation, dizziness, headache, anxiety, nervousness, hostility, insomnia, nausea, dry mouth, vomiting, constipation, EPS.
Nursing interventions: Fewer EPS, > Wt gain, diabetes, hypertriglyceridemia, CVA, mortality

26
Q

Haloperidol (haldol) classification?

A

Atypical antipsychotic

27
Q

Haloperidol (haldol) contraindications?

A

Parkinson’s disease
seizures
CNS depression
alcoholism
mental depression
NMS

28
Q

Haloperidol (haldol) uses/action?

A

Uses: psychotic disorders, tourett’s syndrome, agitation in acute/chronic psychoses, severe behavioral problems w/ children, hostility
Action: Blocks postsynaptic dopamine receptors in limbic system in brain

29
Q

Haloperidol (haldol) ineractions?

A

CNS depressants
opiates
alcohol
anticoagulants
anticholinergics
methyldopa

30
Q

Haloperidol (haldol) side effects?

A

Extrapyramidal symptoms, tardive dyskinesia, photosensitivity

31
Q

Haloperidol (haldol) nursing interventions?

A

Monitor mental status, NMS, EPS, Parkinsonism, exacerbation of seizures, depression.
Lab work: WBC, LFT
no alcohol, driving
Oral hygiene (dry mouth), > fluids
Give with full glass of water, food or milk.

32
Q

Risperidone (risperdal) classification?

A

Atypical antipsychotic

33
Q

Risperidone (risperdal) contraindications?

A

Elderly dementia - psychosis
NMS
CNS depression
head trauma

34
Q

Risperidone (risperdol) uses/action?

A

Schizophrenia
bipolar disorder
irritability w/ autism

35
Q

Risperidone (risperdol) interactions?

A

Antihypertensives
Antiparkinson

36
Q

Risperidone (risperdol) side effects?

A

Fatigue
sedation
drowsiness
headache
insomnia
agitation
EPS
dry mouth
vomiting
Diarrhea
constipation
weight gain
cough

37
Q

Risperidone (risperdol) nursing interventions?

A

Monitor diabetic for loss of glucose control
Monitor CV status, neuro status, orthostatic hypotension, seizure risk
Assess cognitive motor impairment & environmental hazards
No driving until response known
No alcohol

Pharm 2 Exam 1 (4 decks)

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