Coenzymes Flashcards

1
Q

what is the vitamin source of adenosine triphosphate (ATP)?

A

None

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what is the metabolic role of adenosine triphosphate (ATP)?

A

transfer of phosphoryl or nucleotidyl groups

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what is the mechanistic role of adenosine triphosphate (ATP)?

A

cosubstrate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what is the vitamin source of S-adenosylmethionine (SAM)?

A

None

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what is the metabolic role of S-adenosylmethionine (SAM)?

A

transfer of methyl groups

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what the mechanistic role of S-adenosylmethionine (SAM)?

A

cosubstrate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what is the vitamin source of uridine disphosphate glucose?

A

none

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what is the metabolic role of uridine disphosphate glucose?

A

transfer of glycosyl groups

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

what is the mechanistic role of uridine disphosphate glucose?

A

cosubstrate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what is the vitamin source of nicotinamide adenine dinucleotide (NAD+)/nicotinamide adenine dinucleotide phosphate (NADP+)?

A

Niacin (B3)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what is the metabolic role of nicotinamide adenine dinucleotide (NAD+)/nicotinamide adenine dinucleotide phosphate (NADP+)?

A

oxidation-reduction reactions involving two electron transfer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what is the mechanistic role of nicotinamide adenine dinucleotide (NAD+)/nicotinamide adenine dinucleotide phosphate (NADP+)?

A

cosubstrate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what is the vitamin source of flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD)?

A

riboflavin (B2)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what is the metabolic role of flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD)?

A

oxidation-reduction reactions involving one- and two-electron transfers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what is the mechanistic role of flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD)?

A

prosthetic group

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

what is the vitamin source of coenzyme A (CoA)?

A

pantothenate (B5)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

what is the metabolic role of coenzyme A (CoA)?

A

transfer of acyl groups

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

what is the mechanistic role of coenzyme A (CoA)?

A

cosubstrate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

what is the vitamin source of thiamine pyrophosphate (TPP)?

A

thiamine (B1)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

what is the metabolic role of thiamine pyrophosphate (TPP)?

A

transfer of multi-carbon fragments containing a carbonyl group

21
Q

what is the mechanistic role of thiamine pyrophosphate (TPP)?

A

prosthetic group

22
Q

what is the vitamin source of pyridoxal phosphate (PLP)?

A

pyridoxine (B6)

23
Q

what is the metabolic role of pyridoxal phosphate (PLP)?

A

transfer of groups to and from amino acids

24
Q

what is the mechanistic role of pyridoxal phosphate (PLP)?

A

prosthetic group

25
what is the vitamin source of biotin?
Biotin (B7)
26
what is the metabolic role of biotin?
ATP-dependent carboxylation of substrates or carboxyl-group transfer between substrates
27
what is the mechanistic role of biotin?
prosthetic group
28
what is the vitamin source of tetrahydrofolate?
folate
29
what is the metabolic role of tetrahydrofolate?
- transfer of one-carbon substituents, especially formyl and hydroxymethyl groups - provides the methyl group for thymine in DNA
30
what is the mechanistic role of tetrahydrofolate?
cosubstrate
31
what is the vitamin source of cobalamin?
cobalamin (B12)
32
what is the metabolic role of cobalamin?
- intramolecular rearrangements | - transfer of methyl groups
33
what is the vitamin source of lipoamide?
none
34
what is the metabolic role of lipoamide?
oxidation of hydroxyalkyl group from TPP and subsequent transfer as an acyl group
35
what is the mechanistic role of lipoamide?
prosthetic group
36
what is the mechanistic role of cobalamin?
prosthethic group
37
what is the vitamin source of retinal?
vitamin A
38
what is the metabolic role of retinal?
vision
39
what is the mechanistic role of retinal?
prosthetic group
40
what is the vitamin source of vitamin K?
vitamin K
41
what is the metabolic role of vitamin K?
carboxylation of some glutamate residues
42
what is the mechanistic role of vitamin K?
prosthetic group
43
what is the vitamin source of ubiquinone (Q)?
none
44
what is the metabolic role of ubiquinone (Q)?
lipid-soluble electron carrier
45
what is the mechanistic role of ubiquinone (Q)?
cosubstrate
46
what is the vitamin source of heme group?
none
47
what is the metabolic role of heme group?
electron transfer
48
what is the mechanistic role of heme group?/
prosthetic group