Coeliac

Question 1

Coeliac disease

Answer 1

• Non-IgE mediated allergy to gluten
• Associated with:
  
  • Dermatitis herpetiformis
  • Autoimmune conditions
    
    • Type 1 diabetes
    • Hepatitis
    • Thyroid disease
  • IBS
• Antibodies
  
  • IgA tissue transglutaminase (tTG)
  • Endomysial
• Small intestine biopsy
• Gluten-free diet
• Complications
  
  • Anaemia
  • Hyposplenism
  • Osteoporosis/osteomalacia
  • Lactose intolerance
  • Enteropathy-associated T-cell lymphoma of small intestine
  • Subfertility