Coeliac

Question 1

What is coeliac disease?

Answer 1

IgA mediated condition where there is a hypersensitivity to gluten leading to villous atrophy and malabsorption

Question 2

What are the symptoms?

Answer 2

Diarrhoea
Abdominal pain-crampy
FTT in children
Nausea 
Prolonged fatigue
Mouth ulcers
Anaemia
Dermatitis herpetiformis
Rarely neurological symptoms

Question 3

What investigations are needed?

Answer 3

Bloods

• FBC
• U&Es
• LFTs
• B12
• Folate
• Iron
• Total IgA and anti TTG
• -do total IgA as if low then it can cause false negatives

Endoscopy with biopsy is gold standard

• crypt hypertrophy
• villous atrophy

Question 4

What is the management?

Answer 4

Lifelong gluten free diet

• avoid grains
• no bread/wraps/beer/pasta/rye/oats