Coagulation Review Flashcards
________________ hemostasis involves the platelets clumping and adhering to the vessel and the vascular response to injury
Secondary
_________________ effect is the physical effect of the surrounding tissues which seals the vessel
Extravascular
__________ effect involves plasma factors
Intravascular
Vascular effects take effect when _______ from the endothelial membrane is exposed to platelets and they begin to aggregate
Collagen
Anti-thrombin Heparin complex neutralizes _______
Thrombin, factors IXa, Xa, XIa and XIIa
Based on their unique properties the coagulation factors are separated into 3 groups
- Fibrinogen Group
- Prothrombin group
- Contact factors
The coagulation factors are proteins except
Factor IV (Calcium)
What factor is found in the common pathway, is synthesized in the liver, is a heat labile factor, yet is not affected by vitamin K deficiencies?
Factor V
This factor is converted by thrombin to its activated form and it stabilizes the fibrin clot in the common pathway.
Factor XIII
What factor is also known as the Fletcher Factor?
Prekallikrein
Hemophiliac will show a deficiency of what factor
Factor XIII
Factors XII’s activation starts ___________ pathway
Intrinsic
Factor VII is exclusive to the _____________ pathway
Extrinsic
Plasminogen activates to _____________ and is responsible for fibrinolysis or digesting fibrin
Plasmin
___________ is the cessation of blood
Hemostasis
The_________ assures that clots in the body are formed only formed only when needed
Hemostatic mechanism
The body’s complex Hemostatic mechanism can respond in 2 ways. Name the 2 responses and briefly describe each
.
__________ is when a damaged blood vessel contracts to decrease blood flow
Vado constriction
Factor 1 = Sun/gun
Fibrinogen
Factor 2 - Shoe
PT (prothrombin)
Factor 3 - Tree
Tissue Thromboplastin (TT)
Factor 4 - door
Calcium
Factor 5- knive
Proaccerlerin/ Labile factor
LAY-bile ( body laying there stabbed)
Factor 7 Heaven
Proconvertin / STABLE factor