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Phlebotomy > Coagulation Cascade/Factors > Flashcards

Coagulation Cascade/Factors Flashcards

0
Q

Factor IA

A

Fibrin

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1
Q

Factor I

A

Fibrinogen

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2
Q

Factor II

A

Prothrombin

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3
Q

Factor IIA

A

Thrombin

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4
Q

Factor III

A

Tissue Factor

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5
Q

Factor IV

A

Calcium

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6
Q

Factor V

A

Proaccelerin

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7
Q

Factor VI

A

(Not assigned)

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8
Q

Factor VII

A

Proconvertin

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9
Q

Factor VIII

A

Anti-hemophiliac factor

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10
Q

Factor IX

A

Christmas

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11
Q

Factor X

A

Stuart-Prower

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12
Q

Factor XI

A

Plasma

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13
Q

Factor XII

A

Hageman

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14
Q

Factor XIII

A

Fibrin stabilizing factor

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15
Q

What is NAP an acronym for?

A

Nitric oxide
ADP
PGI2

16
Q

What is coagulation (by definition)

A

The process by which soluble fibrinogen is converted into insoluble fibrin

(From I to IA)

17
Q

_____ ________ cells do not tolerate ______ ___________ _______ near them

A

HEALTHY ENDOTHELIAL cells do not tolerate ACTIVATED COAGULATION FACTORS near them

18
Q

Healthy endothelial tissue is…

A

Anti thrombic & anti coagulant

19
Q

The endothelial lining is a…

A

Biological active tissue

20
Q

PT vs PTT

A

PT is the time for plasma to clot, PTT is for blood to clot

21
Q

What is an INtrinsic pathway?

A

Blood clotting on its own without outside factors

22
Q

What is an EXtrinsic pathway

A

A factor besides the blood has initiated coagulation

23
Q

Which pathway, intrinsic or extrinsic, is fastest?

A

Extrinsic is fastest

24
Q

What factor initiates coagulation via extrinsic pathways?

A

Factor 7 (proconvertin)

25
Q

What factor initiates coagulation via intrinsic pathways?

A

Factor XII (Hageman)

26
Q

How big are platelets?

A

2-3 um

27
Q

How long do platelets live?

A

8-10 days

Phlebotomy (2 decks)

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