Coagulation And Coagulpathy Flashcards

1
Q

Treatment for rodenticide toxicity

A

Fluids
Oxygen
Make vomit if early
Blood FFP FWB RBC

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2
Q

What are some coagulation tests?

A
Platelet count 
BMBT
aPTT
PT
ACT
Biochem panel 
TT
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3
Q

What is the cause of IMHA

A

Anemia from destruction of RBC by antibodies

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4
Q

What do you need for platelet count?

What is normal count ?

A
  • EDTA rube
  • smear

10-15 platelets PHF is normal

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5
Q

What is the causes of thrombocytopenia 1-3

A

-1- platelet destruction
2- platelet consumption
3- lowered platelet production

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6
Q

Cause of rodenticide toxicity

A

Lack of activation for vit k and clotting factors

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7
Q

Cause of Von willebrand disease

A

Lack of vWF in blood

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8
Q

What is a platelet and it’s function ?

A

Thrombocyte

Plug holes in damaged vessels to prevent bleeding

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9
Q

Treatment of VWD

A

Blood products

  • FFP
  • RBC
  • Cryo
  • Desmopressin acetate
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10
Q

Signs of clotting/ bleeding disorder

A
Petechia 
Melena 
Haematoma 
Hematuria 
Anaemia 
Bleeding in a few sites
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11
Q

What are the 3 stages of haemostasis

A

1- vasoconstriction
2- primary haemostasis
3- secound art haemostasis

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12
Q

What is anaemia ?

A

Reduced RBC

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13
Q

What diagnostics can be used for IMHA

A

PCV

Blood smear

Haematology

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14
Q

What is primary and secondary coagulation

A

Primary- platelets

Secondary- coagulation factors

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15
Q

Nursing care for blood disorders

A
NO JUGULAR
Small needle 
Pressure on sites 
Min walking/ bubble wrap
Monitor pcv and platelet count 
Min blood sampling
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16
Q

Treatment for IMHA primary and secondary

A

Primary- immunosuppressive drugs

Secondary- find cause

17
Q

Technique for sampling coagulation includes:

A
  • clean venipuncture, new needle each time. If disturbed coagulation occurs, leave and try again if it does.
  • no jugular !
  • anticoagulant tine eg EDTA, citrate
  • send ASAP
18
Q

Diagnostics for VWD

A

Bmbt

vWF levels testing

19
Q

What is haemostasis

A

The prevention of blood loss by sealing sites of injury

20
Q

What are clotting factors ?

A

Other substances in plasma

21
Q

How to diagnose thrombocytopenia

A

Blood smear with platelet count

Bone marrow biopsy

22
Q

Treatment for thrombocytopenia

A
  • immunosuppressive drugs to stop platelet destruction
  • blood products to give platelets. FFP, FWB,PRP
  • stop bone marrow from producing too many via chemo, antibiotics
23
Q

Where do platelets come from

A

Bone marrow

24
Q

What are the three causes for Thrombocytopenia

A

1- platelet destruction
2- platelet consumption
3- low platelet production

25
Q

What does IMHA stand for ?

A

Immune mediated haemolytic anaemia

26
Q

The difference between IMTP and IMHA is what physical sign?

A

IMHA you will see yellow in eyes

27
Q

What are the 3 types of von williebrand disease

A

1-low von will factor
2- large proteins making von are absent
3- no von will

28
Q

PT test extrinsic or instrinsic

A

Extrinsic and common pathway

29
Q

aPTT test extrinsic or instrinic

A

Instrinic and common pathway

30
Q

the TT test stands for what and measures what

A

Theombin time

Functional fibrinogen

31
Q

ACT stands for what and does it test instrinic or extrinsic?

A

Activated clotting time

Instrinic

32
Q

What is the procedure for an ACT test/ material needed

A

Fresh whole blood
37 degree bath
Stop watch
Themonoter

33
Q

What disease can we use PT to test

A

Vit k def

DIC

Liver failure

34
Q

What disease can we use an aPTT test to diagnose

A

DIC dog

HAE a+b

Vit k

35
Q

What does TT thrombin time measure

A

Functional fibrogen