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Pharmacology - Exam 2 (Things You Need To Know) > Coagulants > Flashcards

Coagulants Flashcards

1
Q

What drugs affecting blood coagulation are contraindicated for children?

A

“aban” drugs

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2
Q

Drugs affecting blood coagulation injury prevention

A

Electric razor
Soft bristled toothbrush
No contact sports

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3
Q

Drugs affecting blood coagulation older adults

A

Start low go slow :)

kidney/ liver blood testing

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4
Q

Thromboembolic Disorder

A

Conditions that predispose a person to the formation of clots and emboli

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5
Q

Hemorrhagic Disorder

A

Disorder in which excess bleeding occurs

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6
Q

Antiplatelet

A

Alter the formation of the platelet plug

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7
Q

Anticoagulants

A

Interfere with the clotting cascade and thrombin formation

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8
Q

Thrombolytic Drugs

A

Break down the thrombus that has been formed by stimulating the plasmin system

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9
Q

Antiplatelet Agents
Contraindication

A

Pregnancy and Lactation

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10
Q

Antiplatelet Agents
Action

A

Blocks the receptor site on the platelet membrane which prevents platelets for sticking to together and clumping

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11
Q

Antiplatelet Agents
Drug to drug interactions

A

CYP3A inhibitors or inducers

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12
Q

Antiplatelet Agents
Adverse effects

A

CNS
GI
Bleeding

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13
Q

Antiplatelets
Implementation

A

Mark the chart of any patient receiving this drug
Provide small, frequent meals

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14
Q

Antiplatelet Agents

A

Aspirin
Clopidogrel
Dipyridamole
Eptifibatide
Ticagrelor

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15
Q

Anticoagulant Agents
Drug names

A

“-arin”
Heparin
Warfarin
-”xaban”
Rivaroxaban
Apixaban

Dabigatran

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16
Q

Anticoagulant Agents Adverse effects

A

Bleeding GI upset

Skin: Alopecia and dermatitis

17
Q

Anticoagulant Agents

Drug to drug

A

Heparin: oral anticoagulants, salicylates, penicillins, or cephalosporins

Heparin: nitroglycerin

Warfarin: Number of documented interactions

18
Q

Anticoagulants

Diagnosis

A

Risk for injury

Disturbed body image

Ineffective tissue perfusion

19
Q

Anticoagulants

Adverse effects

A

Pregnancy

Renal &

Hepatic disorders

20
Q

Anticoagulants drug names

A

•“-arin”

Heparin

Warfarin

-”xaban”

Rivaroxaban

Apixaban

Dabigatran

21
Q

Anticoagulants Assessment

A

•Recent history of surgery, active internal bleeding, CVA within the last 2 months, aneurysm, obstetrical delivery, organ biopsy, recent serious GI bleeding, recent major trauma, blood-clotting defects, cerebrovascular disease, uncontrolled hypertension, liver disease

Guaiac test

22
Q

Anticoagulants

Implementation

A

Evaluate for therapeutic effects of warfarin PT of 1.5-2.5x the control value or INR of 2-3

Evaluate for therapeutic effects of heparin- aPTT of 1.5-3x the control value

23
Q

Antidotes for Warfarin and Heparin

A

Warfarin: Vitamin K

Heparin: protamine sulfate

24
Q

Thrombolytic Agents

Drug names

A

•“-ase”

Alteplase

Reteplas

Tenecteplase

Urokinase

25
Q

Thrombolytic Agents

Contraindications

A

Pregnancy

•Any condition that would be worsened by dissolution of clots

26
Q

Thrombolytic Agents

Adverse effects

A

Hypersensitivity – Rash, flushing, bronchospasm, and anaphylactic reaction

Bleeding

Cardiac arrythmias

Hypotension

27
Q

Low-Molecular-Weight Heparins

A

•Inhibit thrombus and clot formation by blocking factors Xa and IIa

28
Q

Low-Molecular-Weight Heparins

Drug names

A

“-parin”

Dalteparin

Enoxaparin

29
Q

Hemorrheologic Agent

Drug name

A

Pentoxifylline

30
Q

Antihemophilic

Drug name

A

“factor”

31
Q

Antihemophilic Agent

Implementation

A

Administer by IV only

Mark the chart of any pt receiving this drug

32
Q

Antihemophilic Agent

Adverse Affects

A

Stinging, itching, and burning at the site of injection

Involve risks associated with the use of blood products

N/V

Headache, flushing, fever, chills, lethargy

33
Q

Hemostatic Agents

A

Aminocaproic acid (systemic)

absorbate gelatin (topical)

thrombin (topical)

34
Q

Hemostatic Agents

Adverse Effects

A

Systemic: Excessive clotting, CNS, GI, weakness, fatigue, malaise, and muscle pain

35
Q

Hemostatic Agents

Drug to drug

A

Systemic: Heparin, oral contraceptives or estrogen

Pharmacology - Exam 2 (Things You Need To Know) (2 decks)

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