Coagulants

Question 1

What drugs affecting blood coagulation are contraindicated for children?

Answer 1

“aban” drugs

Question 2

Drugs affecting blood coagulation injury prevention

Answer 2

Electric razor
Soft bristled toothbrush
No contact sports

Question 3

Drugs affecting blood coagulation older adults

Answer 3

Start low go slow :)

kidney/ liver blood testing

Question 4

Thromboembolic Disorder

Answer 4

Conditions that predispose a person to the formation of clots and emboli

Question 5

Hemorrhagic Disorder

Answer 5

Disorder in which excess bleeding occurs

Question 6

Antiplatelet

Answer 6

Alter the formation of the platelet plug

Question 7

Anticoagulants

Answer 7

Interfere with the clotting cascade and thrombin formation

Question 8

Thrombolytic Drugs

Answer 8

Break down the thrombus that has been formed by stimulating the plasmin system

Question 9

Antiplatelet Agents
Contraindication

Answer 9

Pregnancy and Lactation

Question 10

Antiplatelet Agents
Action

Answer 10

Blocks the receptor site on the platelet membrane which prevents platelets for sticking to together and clumping

Question 11

Antiplatelet Agents
Drug to drug interactions

Answer 11

CYP3A inhibitors or inducers

Question 12

Antiplatelet Agents
Adverse effects

Answer 12

CNS
GI
Bleeding

Question 13

Antiplatelets
Implementation

Answer 13

Mark the chart of any patient receiving this drug
Provide small, frequent meals

Question 14

Antiplatelet Agents

Answer 14

Aspirin
Clopidogrel
Dipyridamole
Eptifibatide
Ticagrelor

Question 15

Anticoagulant Agents
Drug names

Answer 15

“-arin”
Heparin
Warfarin
-”xaban”
Rivaroxaban
Apixaban

Dabigatran

Question 16

Anticoagulant Agents Adverse effects

Answer 16

Bleeding GI upset

Skin: Alopecia and dermatitis

Question 17

Anticoagulant Agents

Drug to drug

Answer 17

Heparin: oral anticoagulants, salicylates, penicillins, or cephalosporins

Heparin: nitroglycerin

Warfarin: Number of documented interactions

Question 18

Anticoagulants

Diagnosis

Answer 18

Risk for injury

Disturbed body image

Ineffective tissue perfusion

Question 19

Anticoagulants

Adverse effects

Answer 19

Pregnancy

Renal &

Hepatic disorders

Question 20

Anticoagulants drug names

Answer 20

•“-arin”

Heparin

Warfarin

-”xaban”

Rivaroxaban

Apixaban

Dabigatran

Question 21

Anticoagulants Assessment

Answer 21

•Recent history of surgery, active internal bleeding, CVA within the last 2 months, aneurysm, obstetrical delivery, organ biopsy, recent serious GI bleeding, recent major trauma, blood-clotting defects, cerebrovascular disease, uncontrolled hypertension, liver disease

Guaiac test

Question 22

Anticoagulants

Implementation

Answer 22

Evaluate for therapeutic effects of warfarin PT of 1.5-2.5x the control value or INR of 2-3

Evaluate for therapeutic effects of heparin- aPTT of 1.5-3x the control value

Question 23

Antidotes for Warfarin and Heparin

Answer 23

Warfarin: Vitamin K

Heparin: protamine sulfate

Question 24

Thrombolytic Agents

Drug names

Answer 24

•“-ase”

Alteplase

Reteplas

Tenecteplase

Urokinase

Question 25

Thrombolytic Agents Contraindications

Answer 25

**Pregnancy** •Any condition that would be worsened by dissolution of clots

Question 26

Thrombolytic Agents Adverse effects

Answer 26

**Hypersensitivity – Rash, flushing, bronchospasm, and anaphylactic reaction** Bleeding Cardiac arrythmias Hypotension

Question 27

Low-Molecular-Weight Heparins

Answer 27

•Inhibit thrombus and clot formation by blocking factors Xa and IIa

Question 28

Low-Molecular-Weight Heparins Drug names

Answer 28

“-parin” Dalteparin Enoxaparin

Question 29

Hemorrheologic Agent Drug name

Answer 29

Pentoxifylline

Question 30

Antihemophilic Drug name

Answer 30

"factor"

Question 31

Antihemophilic Agent Implementation

Answer 31

**Administer by IV only** **Mark the chart of any pt receiving this drug**

Question 32

Antihemophilic Agent Adverse Affects

Answer 32

Stinging, itching, and burning at the site of injection Involve risks associated with the use of blood products N/V Headache, flushing, fever, chills, lethargy

Question 33

Hemostatic Agents

Answer 33

Aminocaproic acid (systemic) absorbate gelatin (topical) thrombin (topical)

Question 34

Hemostatic Agents Adverse Effects

Answer 34

Systemic: Excessive clotting, CNS, GI, weakness, fatigue, malaise, and muscle pain

Question 35

Hemostatic Agents Drug to drug

Answer 35

Systemic: Heparin, oral contraceptives or estrogen