Coagulable Flashcards
1
Q
Factor 5 Leiden
A
Most common heritable hypercoagulable
Results in Factor V that is resistant to being inhibited by protein C
Factor V, after activation, is a cofactor that Xa convert prothrombin to thrombin
2
Q
von Willebrand’s dz
A
Most common inherited coagulopathy
3 types ranging in severity
Type 3 is complete absence of vWF
Treat with a trial of ddAVP which may drive release of vWF from cells
Cryo may have some vWF
Factor 8?
