cnsc all modules Flashcards
what is the first step in refeeding management?
correct deficiencies of potassium, phosphorus, magnesium
When a patient is at risk for refeeding syndrome, initiate dextrose at ____ or initiate kcal provision at ___ kcals/kg.
initiate with 100-150 grams dextrose or 10-20 kcals/kg
total body water females + elderly
50% of LBM
total body water males <70 years old
60% of LBM
ECF (extracellular fluid)
1/3 TBW
ICF (intracellular fluid)
2/3 TBW
water gain (sensible)
800-1500 ml from oral fluid, 500-700 ml from solid food
water gain (insensible)
250 ml from water oxidation
water loss (insensible)
600-900 ml via lungs/skin
weight/age based fluid requirement 18-55 years old
35 ml/kg
water loss (sensible)
800-1500 ml urine, 0-250 ml GI
weight/age based fluid requirement 56-75 years old
30 ml/kg
weight/age based fluid requirement >75 years old
25 ml/kg
holliday-segar method for fluid (adults)
1500 ml fluid for first 20 kg, then add:
</= 50 years: 20 ml/kg remaining
>50 years: 15 ml/kg remaining
factors that increase fluid needs
fever, vomiting, NGT output, ostomy/fistula output, hyperventilation (10-60%), excessive sweating, burns
***fluid needs increase by 12.5% for each 1 degree above normal (fever)
factors that decrease fluid needs
fluid overload, HF, renal failure, SIADH, ascites, anasarca
estimating minimal adult IV fluid needs
1000 ml urine output, add 500 ml for insensible loss, add net GI loss or subtract net GI gain
maintenance fluids
hypotonic (1/2 NS)
resuscitation fluids
isotonic (0.9% NS, LR, plasmalyte)
electrolyte losses in the stomach
Na: 60
Cl: 130
K: 15
HCO3: 0
electrolyte losses in the duodenum
Na: 140
Cl: 80
K: 5
HCO3: 0
electrolyte losses in the pancreas
Na: 140
Cl: 75
K: 5
HCO3: 115
electrolyte losses in the bile
Na: 145
Cl: 100
K: 5
HCO3: 35
electrolyte losses in the ileum
Na: 140
Cl: 104
K: 5
HCO3: 30
electrolyte losses in the colon
Na: 60
Cl: 40
K: 30
HCO3: 0
gastric fluid loss replacement
1/2 NS + 10-20 meq KCl/L
small bowel fluid loss replacement (duodenum, pancreas, bile, ileum)
balanced crystalloid (LR, plasmalyte), bicarb or acetate based customized fluid, 0.9% NS
normal serum sodium
135-145
normal serum potassium
3.5-5
normal serum chloride
98-108
normal serum CO2
23-30
normal serum calcium
9-10.5
normal serum phosphorus
2.5-4.5
normal serum magnesium
1.7-2.4
measure plasma osmolality
2 x (serum Na) + (glucose) / 18 + BUN / 2.8
<280 mOsm/kg = hypotonic
>280 mOsm/kg = isotonic
Na correction in hyperglycemia
((glucose -100) x 0.016) + Na
urine osmolality
> 100 mOsm/kg = inappropriate renal dilution
<100 mOsm/kg = appropriate renal dilution (excessive water intake, polydipsia, beer potomania, low solute intake)
anti-diuretic hormone (ADH)
increases water reabsorption in the kidneys
- pain, stress r/t surgery causes a sustained release of ADH in the first 1-2 days post op causing Na to drop
hypertonic hyponatremia treatment
insulin, dc mannitol
hypotonic hypovolemic hyponatremia treatment
isotonic fluids (0.9% NS, LR), dc diuretics, steroids
euvolemic hyponatremia treatment
fluid restrict +/- loop diuretics, isotonic fluids, NaCl tablets, urea, concentrate PN
hypervolemic hyponatremia treatment
Na and fluid restriction, diuretics, concentrate PN
free water deficit
TBW x ((current Na-140)/140)
what regulates entry of potassium into the cell?
Na-K-ATPase pump
what is responsible for an intracellular shift of potassium?
insulin, catecholamines, alkalosis
what is responsible for an extracellular shift of potassium?
glucagon, acidosis, aldosterone
*acidosis = high serum potassium
10 meq of IV potassium increases serum potassium by ___
0.1 meq/L
management of hyperkalemia
K cocktail if potassium is > 6 meg/L or ECG changes, cellular incorporation (insulin +/- D50, sodium bicarbonate, albuterol), increase elimination (furosemide, HD, Na polystyrene sulfonate)
what increases calcium levels?
vitamin d, PTH
what decreases calcium levels?
calcitonin, phosphorus, pH
peripheral calcium supplement
calcium gluconate
1 gram = 4.65 meq Ca
central calcium supplement
calcium chloride
1 gram = 13.6 meq Ca