CNS stimulants Flashcards
CNS Stimulants Uses.
- )Attention-deficit/hyperactivity disorder (ADHD)
- )Narcolepsy
- )Reversal of respiratory distress.
CNS categories.
1.)Amphetamines .Act on cerebral cortex. 2.)Analeptics, caffeine .Acts on brainstem and medulla. 3.)Anorexiants. .Act on satiety center in hypothalamic and limbic areas
Attention-Deficit/Hyperactivity Disorder
Pathophysiology : Dysregulation of transmitters
Serotonin, norepinephrine, dopamine
Epidemiology: Usually occurs in children before age 7 years
More common in boys
Characteristics: Inattentiveness, inability to concentrate
Restlessness, hyperactivity, impulsivity
Inability to complete tasks, poor coordination
Narcolepsy
Recurrent attacks of drowsiness and sleep during normal waking activities. Driving. Talking. Eating. Standing. Sleep paralysis.
Amphetamines Actions.
Stimulate release of norepinephrine and dopamine
Inhibit reuptake of norepinephrine and dopamine
Amphetamines Side effects.
Tachycardia. Palpitations. Hypertension. Restlessness. Irritability. Confusion. Euphoria. Insomnia. Blurred vision. Dysrhythmias. Tremors Blurred vision. Anorexia. Dry mouth. Weight loss. Diarrhea. Constipation. Erectile dysfunction. Excess use: psychosis
Amphetamine-Like Drugs for ADHD
Methylphenidate
Dexmethylphenidate
Uses: Increase attention span and cognitive performance
Memory, reading
Decrease impulsiveness, hyperactivity, and restlessness
Amphetamine-Like Drugs for Narcolepsy
Methylphenidate
Modafinil
Action—Not fully understood
Uses:Both drugs increase wakefulness in patients with sleep disorders
Methylphenidate (Ritalin)
Action.
Modulates serotonergic pathways by affecting changes in dopamine transport
Methylphenidate (Ritalin)
Uses.
ADHD
Narcolepsy
Increase attention span
Methylphenidate (Ritalin)
Interactions.
Caffeine may increase effects. Increases effects of oral anticoagulants,barbiturate ,anticonvulsants, TCAs, MAOIs. Decreased effects of antihypertensive. May alter insulin effects. Can’t eat cheese or drink wine.
Methylphenidate (Ritalin)
Side Effects.
Tachycardia Palpitations Hypertension Dysrhythmias Restlessness Tremors Irritability *Dizziness Headache Blurred vision Euphoria Confusion Anorexia Dry mouth Diarrhea Constipation Weight loss *Seizure Erectile dysfunction
Nursing Process: Methylphenidate
Assessment:
Assess vital signs to be used for future comparison.
Nursing diagnoses:
Health behavior, risk-prone (impulsiveness, short attention span, distractibility) that interferes with peer relationships, learning, and discipline.
Planning:
Patient’s attention span will increase.
Patient will behave in a calm manner.
Nursing interventions:
Teach patient to take the drug before meals.
Advise patients to avoid foods that contain caffeine.
Report irregular heartbeat.
Record height, weight, and growth of children.
Avoid alcohol, caffeine.
Use sugarless gum to relieve dry mouth.
Do not stop abruptly; taper off to avoid withdrawal symptoms.
Evaluation
Anorexiants
Cause stimulant effect on hypothalamic and limbic areas of brain to suppress appetite
Should not be given to children under 12
Anorexiants Side Effects.
Nervousness Irritability Insomnia Tachycardia Hypertension Palpitations Seizures