CNS Stimulants Flashcards
Methylphenidate
Ritalin
CNS Stim
blocks D/NE reuptake receptors
Mild inhibitor of MAO
ADHD and narcolepsy
Dexmethylpheniate
Ritalin Derivative
CNS Stim
blocks D/NE reuptake receptors
Mild inhibitor of MAO
ADHD and narcolepsy
Mixed Amphetamine Salts
CNS Stim
blocks storage vesicles-increase NE/D release
Block D reuptake
ADHD, wt control, narcolepsy
Dextroampehtatime
Adderall
CNS Stim
blocks storage vesicles-increase NE/D release
Block D reuptake
ADHD, wt control, narcolepsy
Atomoxetine
Non Stim
NE reuptake inhibitor
Adoslescents>adults=2 week lag time
Guanfacine
Non stim
a2 adrenergic agonist
-stim in PFC enhance executive fun, attentiveness, working memory
Clonidine
Non stim
a2 adrenergic agonist
-stim in PFC enhance executive fun, attentiveness, working memory
Bupriopion
Non Stim
DA and NE reuptake inhibitors
Tricyclic Antidepressants
Non Stim
DA and NE reuptake inhibitors
Adipex/Desoxyn
Meth
ADHD/wt control
Drug classes
ALL CLASS 2 (non stims are 4 or less)
-Methylphenidate, amphetamine, meth, coke
Cocaine
topical local anesthetic
inhibits D, NE, 5HT reuptake
Cardiac problems/paranoia
not physio depdence, psychological
hyperthermia (@ OD) more than meth!
4-8 day paranoia vs 1-2wks for meth
Reuptake Transporters of D, NE, 5HT
DAT, NET, SERT
Coke/ampthetamine Mechanism
coke-inhibit DAT, NET, SERT
Amphetamine-inhibit DAT and binds to VMAT=increase DA release into synapse
coke and meth and babies
cross placenta
meth also in breast milk
