CNS/Pain

Question 0

Three main classes of opioid receptors

Answer 0

Mu, kappa, delta

Question 1

Peripheral Nervous System Compounds (3)

Answer 1

Acetylcholine, norepinephrine, and epinephrin

Question 2

Mu Receptors

Answer 2

Responses to activation of mu receptors include analgesia, respiratory depression, euphoria, and sedation

related to physical dependence

Question 3

Kappa Receptors

Answer 3

Produce analgesia and sedation

Question 4

Pure opioid agonists

Answer 4

activate mu and kappa receptors

Cause analgesia, euphoria, sedation, respiratory depression, physical dependence, constipation, etc.

Question 5

Agonist-Antagonist Opioids

Answer 5

When administered alone, produce analgesia

However if it is given to a patient who is taking pure opioid agonist these drugs will antagonize analgesia

Question 6

Pure opioid antagonists

Answer 6

antagonists to mu and kappa receptors, do not produce analgesia

Reverse bad effects of antagonists

Question 7

Adverse effects of opioids

Answer 7

-respiratory depression
-constipation
-orthostatic hypotension
-urinary retention
-cough suppression
-biliary colic
-emesis
-elevation of intracranial pressure
-euphoria/dysphoria
-sedation
-miosis
-birth defects
-neurotoxicity
-