CNS Infections Flashcards
What is meningitis?
Infection of the meninges
Describe the route of infection for meningitis?
Microorganisms reach the meninges either by direct extension from the ears, nasopharynx, cranial injury or congenital meningeal defect or by blood stream spread
2 most common causes of meningitis?
Strep pneumonia and neisseria meningitidis
strep pneuomnia is most common
Describe neisseria meningitidis?
Gram negative cocci in pairs
Describe how neisseria meningitidis probably causes meningitis?
Can be found in the throats of healthy carriers
The bacteria probably gain access to the meninges through the bloodstream
Symptoms are due to the bacteria endotoxin
Neisseria meningitidis is more common in ________ and can be _________
young children and adults
responsible for outbreaks
Describe the capsular groups of neisseria meningitidis and the vaccine?
There are 12 capsular groups there is currently a vaccine for ACWY
What causes the classic non blanching rash of meningitis?
Neisseria meningitidis infection that gets in the blood
Neisseria meningitidis is also referred to as?
meningococcus
Describe strep pneumonia?
Alpha haemolytic gram positive cocci in chains
Who has a higher risk of developing strep pneumonia meningitis?
Those with diabetes, skull fractures of cochlear implants
Describe haemophilus influenza meningitis?
Now a vaccine for HiB so not as common
Describe listeria moncytogenes?
gram positive bacilli
Who does listeria monocytogenes tend to cause meningitis in?
neonates, elderly, immunosuppressed, particularly those with malignancy
Give an example of an organism that can cause chronic meningitis?
Tuberculosis