CNS Final Exam Flashcards
The “roof” of the midbrain
Tectum
Posterior to the CEREBRAL AQUEDUCT (of Sylvius)
Tectum
The tectum contains this important reflex structure
QUADRIGEMINAL PLATE made up of the 4 colliculi (2 inferior and 2 superior)
This structure of the tectum deals with seeing and visual input
Superior colliculi
This structure of the tectum deals with hearing or auditory input
inferior colliculi
This part of the midbrain connects the 3rd and 4th ventricles
Cerebral Aqueduct (of Sylvius)
Serves as a channel for CSF exchange between the third and 4th ventricles
Cerebral Aqueduct (of Sylvius)
This structure surrounds the cerebral aqueduct
Periaqueductal gray
Periaqueductal gray is the apparent origin for what cranial nerves
Cranial nerve nuclei III and IV
Endorphins and enkephalins are also found here
This midbrain structure is located ventral to the cerebral aqueduct
cerebral peduncles
This structure of the cerebral peduncles (of midbrain) is located VENTRAL to the aqueduct
Tegmentum
A structure of the cerebral peduncles that contains the MEDIAL LEMNISCUS and includes the inferior part of the PERIAQUEDUCTAL GRAY and RED NUCLEUS
Tegmentum
This structure of the midbrain’s cerebral peduncles is located toward the MIDDLE of the peduncle and in the SUPERIOR part of the Diecephalon
Substantia Nigra
This midbrain structure separates the tegmentum from the curs cerebri
Substantia nigra
This midbrain structure is found on the VENTRAL and lateral aspect of the cerebral peduncles
Crus cerebri
This cranial nuclei is located on the POSTERIOR aspect of the brainstem and is the SMALLEST of the cranial nerves
Cranial Nerve IV (Trochlear N)
This cranial nerve innervates the SUPERIOR OBLIQUE of the extraocular eye muscles
Cranial nerve IV (trochlear N)
The apparent origin of this cranial nerve is out of the mid-dorsal aspect just INFERIOR to the INFERIOR COLLICULUS (fibers cross over for the OPPOSITE side of this bilateral nerve)
Cranial nerve IV (Trochlear N)
ONLY cranial nerve to have its’ origin on the POSTERIOR side of the brainstem
cranial nerve IV (trochlear N)
ONLY cranial nerve to CROSS over as it EXITS the CNS
Cranial nerve IV (trochlear N)
Travels FURTHER INSIDE the cranial vault than any other cranial nerve
Cranial nerve IV (trochlear n)
Unique characteristics of Cranial Nerve IV (Trochlear N)
- Smallest CN
- Only one with apparent origin on the posterior side of the brainstem
- fibers cross over as they EXIT the CNS
- Travels further inside the cranial vault than any other CN (Longest in the cranial vault)
Called the OCULOMOTOR nerves located in the ANTERIOR part of the brainstem
Cranial nerve III (oculomotor)
Apparent origin is ventral to the INTERPEDUNCULAR FOSSA (into the cistern)
Cranial nerve III (oculomotor)
Six nuclei of origin are found here in the periaquectal gray substance
Cranial nerve III (oculomotor)
This cranial nerve innervates 4 of the 6 extraocular muscles
cranial nerve III
What are the 4 muscles supplied by the oculomotor nerve?
Superior rectus
inferior rectus
medial rectus
inferior oblique
Raises the upper eyelids and receives somatic motor fibers from cranial nerve III
Levator palpebrae superioris
Carries PRE-GANGLIONIC PARAsympathetic (involuntary axons) from the accessory oculomotor nucleus (edinger-westphal to the cilliaris and sphincter pupillae
cranial nerve III
Another name for the accessory oculomotor nucleus
Edinger-Westphal nucleus
pupillary constriction muscles of the eye
sphincter pupillae
cell bodies of this nucleus originate in the CNS and synapse outside the CNS and release ACh
Oculomotor nucleus (Edinger-Westphal)
Inferior and superior colliculi use this tract for protective relfexes
Tectospinal tract
Tectospinal tract influences these neurons
Neurons in the UPPER cervical through cranial nerve XI
Tract that contracts the SCM and trapezius muscles
Tectospinal tract
Nerve that innervates the SCM and the trapezius muscles
Spinal accessory nerve (CN XI)
Lesions to the TECTUM will impair these type of functions
Inhibit the PERCEPTION of motion of objects in the field of vision and NOT voluntary eye movements
In this pathway the fibers enter the lateral lemniscus and ascend to the MEDIAL geniculate body in the thalamus and terminate in the temporal lobe
Conscious Lateral lemniscus pathway (hearing reflexes)
In this pathway the fibers ever the lateral lemniscus and ascend to two different areas:
1) inferior colliculus and ascends to the MEDIAL geniculate body of the thalamus and terminates in the temporal lobe
2) inferior colliculus and then the superior colliculus and terminates in the tectospinal tract (involves SCM and trapezius)
UNCONSCIOUS lateral lemniscus (hearing) pathway
-activated when you are startled by a loud sound
Auditory input goes to this part of the thalamus
medial geniculate body
Visual input goes to this part of the thalamus
Lateral geniculate body
In this pathway the fibers enter the optic tract and synapse in the lateral geniculate body of the thalamus and terminate in the occiptial lobe
CONSCIOUS optic tract pathway (vision)
In this pathway the fibers enter the optic tract and synapse on the superior colliiculus of the tectum and synapse in the tectospinal tract and terminate in the spinal nucleus of the accessory nerve (lower motor neuron)
UNCONSCIOUS optic tract pathway (vision)
-activated when you are startled by visual inputs)
The reticular nucleus of the midbrain is located here
Tegmentum of the cerebral penduncles
Structures of the cerebral penduncles of the midbrain
- tegmentum
- substantia nigra
- crus cerebri
Nucleus found in the cerebral peduncles that may or may not be considered part of the reticular formation.
Red nucleus (Nucleus Ruber)
Red nucleus is divided into two parts
Magnocellular area (inferior) Parvocellular area (superior)
Large area making up part of the red nucleus of the tegmentum where rubrospinal tract fibers originate
Magnocellular area
Superior area of the red nucleus that is HIGHLY vascular and is the PRIMARY output form the red nucleus
Parvocellular area
Input fibers come to the red nucleus from these areas
Central cerebellar nuclei [(dentate, interposed nuclei) EXCEPT for fastigial] and the cerebral cortex
Functions of the red nucleus
Contralateral motor responses necessary for POSTURAL and MUSCLE control primarily in the FLEXOR musculature
Structure of the cerebral peduncles located between the tegmentum and crus cerebri and extends into the subthalamus of the diencephalon
Substantia nigra
Substantia nigra is called the black substance because of this chemical
Melanin
This neurotransmitter is secreted in the Substantia nigra from tyrosine and produces melanin as a result
Dopamine
Afferent and efferent fibers are exchanged between the telencephalon’s caudate and putamen nuclei in this part of the cerebral peduncle
Substantia nigra
Substantia nigra and parkinson’s disease
In this disease the body is unable to synthesize dopamine as a result of damage to the substantia nigra. (symptoms include shaking of digits, hands and tongue at rest)
These cells appear with Parkinson’s disease. First appear in the old factory bulb and continue to invade the vagus nerve and then into the brainstem and then into the substantia nigra
Lewy bodies
This structure of the cerebral penducle is found on the ventrolateral aspect of the peduncle
Crus cerebri
Composed of DESCENDING PYRAMIDAL tracts (UMN) of fibers from the cerebral cortex
Crus cerebri
Descending pyramidal fibers found in the crus cerebri
Corticospinal fibers
Corticopontine fibers
Corticobulbar fibers
Corticomesencephalic fibers
These fibers are pyramidal fibers that are found in the crus cerebri
Corticospinal fibers
These fibers can synapse on pontine nuclei and are found in the crus cerebri
Corticopontine fibers
These descending pyramidal fibers synapse in the M.O. and are found in the crus cerebri
Corticobulbar fibers
These fibers have axons that terminate on cranial nerve nuclei III and IV to initiate VOLUNTARY motor movements of the eyes and are located in the crus cerebri
Corticomesencephalic fibers
Secondary embryonic vesicle from the prosencephalon and it means “between brain” or between the great cerebral hemispheres
Diencephalon
Major parts of the diencephalon
Third ventricle epithalamus thalamus hypothalamus subthalamus
This is the MOST significant RELAY center for SENSORY input to the CEREBRUM (all sensation except oldfaction)
DIencephalon
This structure is just superior to the midbrain and tectum
Epithalamus
The “epiphysis cerebri” that is filled with very highly modified neurons called pineal or epiphyseal cells. Located in the epithalamus
Pineal gland
Built like an endocrine gland with fenestrated capilllaries.
Pineal gland
Pineal gland is not directly sensitive to light but through a pathway originating in the retina and synapsing in the hypothalamus in this nucleus
Suprachiasmatic nucleus
This neurotransmitter levels appear to be a function of the circadian cycle and NOT a controller of the cycle
Melatonin
This disorder affects about 1 in 20 people in the US and Canada
Seasonal affective disorder (SAD)
Calcifications of the pineal gland occur with age
Brain sand
This is a small commissure that is found SUPERIOR to the midbrain’s tectum
Posterior commissure
Posterior commissure contains the cell bodies for these cranial nerves
Cranial nerve III (sensory motor) and cranial nerve II (motor eye)
Pupillary light reflex fibers and nuclei are located here
Posterior commissure
This is found just anterior and inferior to the posterior commissure. It may produce adlosterone
Subcommissural organ
Composed of specialized ependymal cells
Subcommissural Organ
Redundancy and rewiring may be methods of this:
Plasticity
This is an injury to the brain caused by traumatic bio-mechanical forces
Mild Traumatic Brain Injury
Loss of consciousness, amnesia, cognitive problems (foggy, hard time concentrating), difficulty remembering are symptoms of:
Mild Traumatic Brain Injury
Another name for the massa intermedia
Interthalamic adhesion
These connect adjacent or nearby gyri
Short Fibers
These connect distal parts of the same hemisphere
Long Fibers
Candidates for surgery of the corpus callosum usually are suffering from
Severe Seizure Disorders
This typically manifests in the non dominant hand of someone who has had surgery on the corpus callosum
Alien Hand Syndrome
The ONLY type of sensory input that is NOT relayed to the thalamus
Oldfaction input
A single structure composed of two large ovoid masses of gray matter that are joined together by bridge of gray matter
Thalamus
This structure holds together the two ovoid masses of the thalamus
Massa intermedia
Another name for the massa intermedia
Interthalamic adhesion
This structure of the diencephalon forms the bulk of the lateral walls of the THIRD ventricle
Thalamus
Efferents of the globus pallidus are also often called
Pallidalfugal fibers
This structure of the thalamus contains descending pyramidal fibers
Internal capsule
The general functions of the thalamus include
Relay of ALL sensory input to the cerebral hemispheres
Helps focus attention of the cerebral cortex
Some pain and temperature sensations are interpreted here
Activity of this is associated with increased inhibition, this is what allows us to sense fear and anger.
Amygdala
A subdivision of the thalamus that contains myelinated fibers running through the substance of each thalamic mass and helps divide them into subdivisions. Carries info in and out of the thalmus
Internal medullary laminae
Largest part of the thalamus and is found among the highest of primates
Pulvinar
A subdivision of the thalamus that is called “hypo” or below the thalamus
Hypothalamus
Forms the floor of the THIRD ventricle and portions of the lateral walls of the third ventricle
Hypothalamus
Contains the infundibular stalk and optic chiasma (NOT the pituitary gland)
Hypothalamus
Hypothalamus is divided into these three areas
Anterior area
Intermediate area
Posterior area
The caudate and putamen together make up this:
neostriatum
These areas of the hypothalamus control parasympathetic functions
anterior and intermediate areas
This area of the hypothalamus controls sympathetic functions
Posterior area
The hypothalamus has endocrine control both directly and indirectly
Directly–via neuron extensions into posterior pituitary
Indirectly–via neurohormones to control release of anterior pituitary hormones
Posterior pituitary is also called
Neurohypophysis
This nucleus is responsible for the CIRCADIAN RHYTHMS such as temperature, sleep, light, and feeding
Suprachiasmatic nucleus (anterior area)
The head of the caudate nucleus is continuous with what other nucleus via gray matter bridges
Putamen
This area of the hypothalamus is found just above the optic chiasma
Anterior area
This nuclei of anterior area (of hypothalamus) contains axons that descend through the infundibular stalk via the hypothalamohypophyseal or supra-optichypophyseal tract
Supraoptic and Paraventricular nuclei