CNS Drugs Flashcards
Serotonin Syndrome
FAT CHD
Fever
Agitation
Tremor
Clonus
Hyperreflexia
Diaphoresis
Cyproheptadine: first line treatment
TCA toxicity
3Cs: Coma, Cardiotoxicity, Convulsions
Serotonin antagonist causing priapism
Tranzodone
Bupropion
MOA: inhibits dopamin and norepinephrine neuronal reuptake
Indication: Smoking cessation
Typical antipsychotic with the least EPS risk
Thioridazine
- most muscarinic blockade
- also causes pigmentary retinopathy
Drug of choice for refractory and suicidal schizophrenia
Clozapine
SE: Agranulocytosis
Antipsychotics with highest risk for weight gain
Clozapine and Olanzapine
Only approved antipsychotic for Schizophrenia in young patients
Risperidone
Single most effective agent for Parkinson’s
Levodopa
Benzodiazepine indicated for alcohol withdrawal
Chlordiazepoxide
Antidote for Benzodiazepine overdose
Flumazenil
Drug of choice for neonatal seizures
Phenobarbital
Drug of choice for methanol and ethylene glycol poisoning
Fomepizole
First line drug for absence seizures
Ethosuxamide
Inhaled anesthetic that increases ICP
Nitrous oxide
*also the least cardiotoxic
DOC for trigeminal neuralgia
Carbamazepine
Most teratogenic AED
Valproic acid
First line for neuropathic pain
Gabapentin, Pregabalin
SE-AED
Gingival hyperplasia
SJS
Acute intermittent porphyria
SE-AED
Gingival hyperplasia: Phenytoin
SJS: Carbamazepine
Acute intermittent porphyria: Barbiturates
