CNS anatomy Flashcards
Falx cerebri
- projects downwards to separate the right and left cerebral hemispheres.
Tentorium cerebelli
- separates the occipital lobes from the cerebellum
- contains tentorial notch
Periosteal dura mater
- Outermost layer of dura mater
- Dura mater is thick, tough and inextensible
- lines the inner surface of the bones of the cranium.
Meningeal dura mater
- located deep to the periosteal layer
- continuous with the dura mater of the spinal cord.
Arachnoid mater
- Arachnoid mater is the middle layer of the meninges
- Lies directly underneath the dura mater
- Consists of layers of connective tissue
- Avascular
- Does not receive any innervation.
Pia mater
- Located underneath the sub-arachnoid space
- Very thin, and tightly adhered to surface of brain and spinal cord.
- Follows contours of the brain (the gyri and fissures).
- Highly vascularised
Subdural space
- a potential space that can be opened by the separation of the arachnoid mater from the dura mater
Subarachnoid space
- contains cerebrospinal fluid, which cushions the brain. - small projections of arachnoid mater into the dura (arachnoid granulations)
- allow CSF to re-enter the circulation via the dural venous sinuses.
Tentorial notch
- Space found anteromedially in tentorium cerebelli for passage of the midbrain.
Superior sagittal sinus
- Dural venous sinus
- Runs through the groove for superior sagittal sinus
- Appears triangular in cross section
Inferior sagittal sinus
The inferior sagittal sinus is a dural venous sinus found within the inferior, free margin of the falx cerebri
Straight sinus
The inferior sagittal sinus and the great cerebral vein join together to form the straight sinus.
Transverse sinuses
- runs through the tentorium cerebelli
- collect the blood from the veins of the cerebellum and inferior surface of the brain
Cavernous sinus
- Contains several key structures: abducens nerve, carotid plexus, internal carotid artery
- Lateral wall contains: oculomotor nerve, trochlear nerve, ophthalmic and maxillary branches of trigeminal nerve
Confluence of sinuses
- Straight, superior, and inferior sagittal sinuses converge at confluence of sinuses
- Overlies the internal occipital protuberance
Sigmoid sinuses
- One of the dural venous sinuses
Cerebrum
-Largest part of the brain, located superiorly and anteriorly in relation to the brainstem.
- It consists of two cerebral hemispheres (left and right), separated by the falx cerebri of the dura mater.
Diencephalon
- Caudal part of forebrain
- Consists of thalamus and hypothalamus (and other structures but don’t need to know)
Brainstem
- Distal part of brain that consists of midbrain pons, and medulla oblongata
Cerebellum
- Important role in motor control
- Sits inferior to occipital and temporal lobes, within the posterior cranial fossa.
- It is separated from these lobes by the tentorium cerebelli, a tough layer of dura mater.
Spinal cord
Midbrain
- Acts as a conduit between the forebrain above and the pons and cerebellum below.
Pons
- The pons is the largest part of the brainstem
- CN V, VI, VII, VIII emerge from the pons
- Houses main sensory nucleus, trigeminal motor nucleus, abducens nucleus, facial nucleus, cochlear and vestibular nuclei
Medulla
- Houses essential ascending and descending nerve tracts as well as brainstem nuclei.
- Contains pyramids, through which upper motor neurones descend
Central sulcus
- Groove separating the frontal and parietal lobes.
Longitudinal fissure
- Separates cerebral hemispheres
Lateral fissure
- Separates frontal and parietal lobes
Frontal lobes
- Responsible for higher intellect, personality, mood, social conduct and language
Temporal lobes
- Responsible for memory and language including hearing (location of the primary auditory cortex).
Parietal lobes
- Responsible for language and calculation on the dominant hemisphere side, and visuospatial functions on the non-dominant hemisphere side
Occipital lobes
- The primary visual cortex (V1) is located within the occipital lobe
- Responsible for vision.
Pre- and postcentral gyri
- Precentral gyrus – location of primary motor cortex.
- Postcentral gyrus – location of primary somatosensory cortex.
Cingulate gyrus
- Part of limbic system
- Isthmus is continuous inferiorly with parahippocampal gyrus in the temporal lobe of the human brain.
Parahippocampal gyrus
- Part of limbic system
Uncus of temporal lobe
- Extremity of parahippocampal gyrus
- If it herniates, CN III can be compressed
- Contains olfactory cortex
Calcarine sulcus
- Location of primary visual cortex
Parieto-occipital sulcus
- Marks boundaries between parietal and occipital lobes
Corpus callosum
- Large white matter tract that connects the two hemispheres of the brain.
Anterior and posterior commissures
- Work together to link the cerebral hemispheres of the brain
- Interconnects amygdalae and temporal lobes
- Contributes to memory, emotion, speech and hearing.
Septum pellucidum
- A thin, triangular, vertical membrane separating the anterior horns of the left and right lateral ventricles of the brain.
Lateral ventricles
- The left and right lateral ventricles are located within their respective hemispheres of the cerebrum.
- They have ‘horns’ which project into the frontal, occipital and temporal lobes.
Third ventricle
- The lateral ventricles are connected to the third ventricle by the foramen of Monro.
- The third ventricle is situated in between the right and the left thalamus.
Cerebral aqueduct
- Connects third ventricle to fourth ventricle
Fourth ventricle
- Lies within the brainstem, at the junction between the pons and medulla oblongata.
- Fluid then drains into central spinal canal and subarachnoid cisterns
Thalamus
- Situated at core of diencephalon
- Grey matter
- Relays and integrates a myriad of motor and sensory impulses between the higher centres of the brain and the peripheries.
Hypothalamus
- Has connections with the endocrine, autonomic (visceral motor), somatic motor, and limbic systems, maintaining a state of homeostasis.
- Controls body temperature, blood circulation, food intake, fluid and electrolyte balance, the sleep-wake cycle, metabolism and sexual behaviour.
Pineal gland
- Produces melatonin
- Tucked in a groove where 2 halves of the thalamus join
Pituitary gland
- Located in sella turcica of sphenoid bone
- Anatomically and functionally closely related to the hypothalamus.
- Anterior portion secretes pituitary hormones
Optic chiasm
- Fibres of the optic nerve (CN II) extend posteriorly from each eye and intersect within the middle cranial fossa, forming the optic chiasm.
- Located at the base of the brain, just anterior and inferior to the location of the pituitary gland.
Fornix
- Found in the mesial aspect of the cerebral hemispheres, below the corpus callosum
- Connects hippocampus to various cortical structures
- Associated with the processes of cognition, memory consolidation, emotions and sexual responses
Cerebellar tonsils
- Can herniated through foramen magnum
Cerebellar peduncles
- Connect cerebellum to brainstem
Vermis
Found in the middle of the cerebellum
Olfactory nerve
Smell
Optic nerve
- Transmits special sensory information for vision
Oculomotor nerve
It provides motor and parasympathetic innervation to some of the structures within the bony orbit.
Trochlear nerve
- Innervates superior oblique (depresses and intorts eyeball)
Trigeminal nerve
- Innervate the skin, mucous membranes and sinuses of the face.
- Mandibular branch innervates muscles of mastication: medial pterygoid, lateral pterygoid, masseter and temporalis.
- Also supplies anterior belly of digastric and tensor tympani.
Abducens nerve
- Innervates lateral rectus muscle (abducts eyeball)
Facial nerve
- Supplies muscles of facial expression, posterior belly of the digastric, stylohyoid and stapedius muscles
- Provides special taste sensation to the anterior 2/3 of the tongue via the chorda tympani
Vestibulocochlear
- Hearing and balance
Glossopharyngeal
- Innervates the oropharynx, carotid body and sinus, posterior 1/3 of the tongue, middle ear cavity and Eustachian tube.
- Provides taste sensation to the posterior 1/3 of the tongue.
- Innervates parotid gland.
- Innervates the stylopharyngeus muscle of the pharynx.
Vagus
- Innervates skin of the external acoustic meatus and the internal surfaces of the laryngopharynx and larynx. Provides visceral sensation to the heart and abdominal viscera.
- Provides taste sensation to the epiglottis and root of the tongue.
- Provides motor innervation to the majority of the muscles of the pharynx, soft palate and larynx.
Parasympathetic: Innervates the smooth muscle of the trachea, bronchi and gastro-intestinal tract and regulates heart rhythm.
Accessory nerve
- Innervates sternocleidomastoid and trapezius muscles.
Hypoglossal nerve
- Innervates all the extrinsic and intrinsic muscles of the tongue
Cervical enlargement
- Located proximally, at the C4-T1 level.
- It represents the origin of the brachial plexus.
Lumbar enlargement
- Between T11 and L1 is the lumbar enlargement,
- It represents the origin of the lumbar and sacral plexi.
Conus medullaris
At the L2 vertebral level the spinal cord tapers off, forming the conus medullaris.
Filum terminale
- Formed distally by meninges
- Strand of fibrous tissue
- Attaches to the vertebral bodies of the coccyx
- Acts as an anchor for the spinal cord and meninges.
Lumbar cistern
- This space is accessed during a lumbar puncture (to obtain CSF fluid) and spinal anaesthesia.
Cauda equina
- A bundle of spinal nerves that arise from the distal end of the spinal cord.
- They run in the subarachnoid space, before exiting at their appropriate vertebral level.