CNS Flashcards

1
Q

intracranial HTN cut off

A
  1. 40 is severe(ischemia)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

signs of elevated ICP

A

HA/nausea then decreasing consciousness then coma/cushing response and motor posturing

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

normal ICP

A

5-10

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

cerebral auto regulation range

A

50-150

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

cerebral steal

A

vasodilation that occurs in healthy region of brain during period of ischemia. so pulls blood flow from ischemia to healthy brain. so ischemia gets even worse blood flow.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

inverse cerebral steal/robin hood

A

vasoconstriction caused by hyperventilation or drug that causes vasoconstriction in healthy area to have more flow go to ischemia area

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

how much oxygen and glucose does brain get over needed

A

3x oxygen and 7x glucose during normal activity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

CBF numbers

A

50mL/100g/min. gray matter is 80, white is 20

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

CBF per min

A

750mL/min

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

CBF ischemia numbers by 100g

A

20-30 start of neuro symptoms. 15-20 isoelectric EEG, no evoked potentials. 10-15 Na/K pump fail, cytotoxic edema. less than 10 is irreversible damage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

CSF volume

A

124-150mL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

CSF production per hour

A

20-30cc

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what makes CSF

A

choroid plexus ependymal cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

pH of CSF

A

7.32

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

IV anesthetics that stand out brain

A

ketamine up CBF. etomidate can precipitate seizure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

worst volatile that causes cerebral vasodilation mor

A

halothane. best is sevo

17
Q

volatile that is epileptogenic

A

enflurane

18
Q

volatile we use that up CBF

A

des over 1 MAC

19
Q

PaCO2 goal for craniotomy

A

linear relationship between PaCO2 and CBF from 30-60. under 30 no change so keep at 30

20
Q

how many vertebrae

A

33

21
Q

how many spinal nerve pairs

A

31

22
Q

which tract crosses in cord

A

sensory

23
Q

how to know where autonomic dysreflexia starts

A

happens w/ injury above T6. flushing above injury(parasympathetic) and vasoconstriction below(sympathetic

24
Q

collateral spinal blood flow worst where

A

T1-4

25
Q

which system has ganglia in the organ

A

parasympathetic

26
Q

sympathetic chain in cord location

A

T1 to L2

27
Q

what nerves have acetylcholine

A

all parasympathetic and pre ganglionic sympathetic

28
Q

a1 receptor job

A

vascular smooth muscle constriction

29
Q

a2 receptor job

A

found on pre synaptic neuron and inhibit release of norepi

30
Q

b1 receptor job

A

up contractility and HR. too much can cause arrhythmia

31
Q

b2 receptor job

A

vascular and non vascular smooth muscle relaxation

32
Q

alpha brain wave

A

Awake-resting

33
Q

beta brain wave

A

Busy, thinking

34
Q

theta waves

A

GETA. general anesthesia

35
Q

delta waves

A

Deep sleeping-general anesthesia

36
Q

anesthetic agents other than increase latency/decrease amplitude. SSEP

A

NO latency no change, down amp. etomidate up both. ketamine up amp. opioid and muscle relaxant no changes

37
Q

type of greatest heat loss during GA

A

radiation

38
Q

factors that are synthesized in liver

A

2, 5, 7, 9, 10, 11 and 12