CN IV Palsy Flashcards

1
Q

What are the primary, secondary and tertiary actions of the superior oblique muscle?

Innervated by CN IV

A
  • primary: intorsion
  • Secondary: depression
  • Tertiary: abduction
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2
Q

3 unique characteristics of CN IV

A
  1. longest intracranial course
  2. thinnest nerve (in terms of number of fibers)
  3. Only CN that decussates and exits at the dorsal aspect of the brainstem
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3
Q

Normally, when the head tilt, the eye on top extorts/intorts and the eye on the bottom extorts/intorts

A

top eye extorts; bottom eye intorts

extort: IO and IR laterally rotate away from note

intort: SO and SR laterally rotate toward nose

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4
Q

In a LEFT CN IV palsy, there will a be a RIGHT hyper/hypo tropia and extorsion/intorsion in primary gaze

A

hypertropia; extorsion

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5
Q

Vertical diplopia with a CN IV palsy is greater at near/distance

A

near

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6
Q

Because objects will appear tilted to someone with a CN IV palsy, they will develop a compensatory head tilt toward/ away from the affected side

A

away

Right CN IV palsy develops head tilt to the left

CN IV: TILT AWAY to relieve torsional diplopia

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7
Q

Park’s 3-Step test is useful to detect what?

A

A single paretic vertical muscle

SO

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8
Q

How is Park’s 3-Step done?

A

Perform ACT is primary gaze, right and left gaze, and with head tilted right and left

detects small deviations, tests for comitancy and quantifies devation

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9
Q

A patient with a RIGHT CN IV palsy will have hypertropia worse in which gaze/ head tilt?

A

Left gaze; right head tilt

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10
Q

What is a subjective measurement of the angle of excyclotorsion?

A

Bilateral Maddox Rod

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11
Q

What is an objective way to measure the angle of excyclotorsion?

A

Fundus photos

Normal Fundus: fovea slightly lower than optic disc; excyclotorsion: fovea will present as markedly lower

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12
Q

What does it mean if the objective measurement of the angle of excyclotorsion equals the subjective measurement?

A

Recent onset SO palsy

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13
Q

What does it mean if the objective measurement of the angle of excyclotorsion is greater than subjective?

A

Longstanding SO palsy

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14
Q

What will subjective and objective testing look like when the SO palsy is congenital?

A

Will only notice the objective measurement; patient will not report anything for subjective

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15
Q

3 most common etiologies of CN IV palsy?

A

congenital, traumatic, ischemic

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16
Q

3 causes of congenital CN IV Palsy?

A
  1. hypoplasia of trochlear nucleus
  2. anaomalies of the SO muscle
  3. Birth Trauma
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17
Q

What physical characteristics might someone with congenital CN IV palsy present with?

A

mild facial symmetry; long-standing head tilt

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18
Q

Vertical vergence ranges are small/ large in congenital CN IV Palsy

A

Large

10-15 PD

19
Q

Why is CN IV vulnerable to trauma?

A

long course and surrounding structures

20
Q

What can happen to CN IV at the free tentorial edge

A

compression

21
Q

What can happen to CN IV at the ambient cistern?

A

Subarachnoid hemorrhage

22
Q

What is the laterality of traumatic CN IV palsy?

A

unilateral or bilateral

23
Q

What is the prognosis for traumatic CN IV palsy?

A

partial or complete resolution

24
Q

What systemic diseases are often see with ischemic CN IV Palsy?

A

microvascular disease

HTN, DM, atherosclerosis, smoking

25
Q

What is the onset of diplopia associated with ischemic CN IV Palsy?

A

Acute

no other CN involvement, neurologic signs or symptoms

26
Q

What are the fusional ranges associated with ischemic CN IV Palsy?

A

Normal

27
Q

How long does it take for ischemic CN IV Palsy to resolve?

A

3-4 months

28
Q

What are the 5 syndromes of CN IV Palsies?

A
  1. Nuclear-fascicle syndrome
  2. subarachnoid space
  3. cavernous sinus syndrome
  4. orbital syndrome
  5. isolated CN IV palsy: acquired and congenital
29
Q

What neurologic signs are associated with Nuclear-Fascicular CN IV palsy?

A

there are none

30
Q

Is the CN IV palsy ipsilateral or contralateral to the lesion in nuclear-fascicular CN IV Palsy?

A

contralateral

fasicicles from nucleus decussate to innervate contralateral SO

31
Q

Does Horner’s syndrome occur ipsilateral or contralateral to the lesion in nuclear-fascicular CN IV Palsy?

A

Ipsilateral

oculosympathetic pathways descend through the dorsolateral tegmentum of the midbrain adjacent to the trochlear fascicles

32
Q

What is the most common cause for the bilateral CN IV palsy that occurs within the subarachnoid space?

A

Trauma

contracoup forces by the tentorial edge injur the nerves at this site

less frequent causes: subarachnoid hemorrhage, tumor and meningitis
Trauma is the most common cause of CN IV palsy in adults

33
Q

If someone presents with bilateral CN IV Palsy, what else should we look for?

A

Dorsal Midbrain syndrome

34
Q

What is the clinical picture of subarachnoid CN IV palsy?

A
  • LND pupils
  • Collier’s lid tuck in upgaze (lid retraction with limited upgaze)
  • LHyper greater in left head tiltand right gaze
  • RHyper greater in right head tilt and left gaze
  • > 10 degrees of excyclotorsion
35
Q

When is observation only acceptable in CN IV palsy?

A

unilateral cases: with established history of trauma or with increased vertical vergences

36
Q

When does isolated, unilateral palsy withOUT trauma need to be worked up?

A

When there are no obvious microvascular ischemic or other risk factors

Work up: BP, Glucose tolerance test, CBC with diff, ESR/ CRP, RPR, FTA-Ab, ANA

37
Q

When is neuroimaging ordered in CN IV Palsy in adults?

A
  • bilateral
  • evidence of dorsal midbrain syndrome
  • involvement of other crainial nerves
  • ischemic palsy suspected, but not resolving in 3-4 months
38
Q

What is the most common cause of CN IV Palsy in Children?

A

Congenital

39
Q

When are children with CN IV palsy observed only?

No workup ordered

A
  • Unilateral with established history of trauma
  • Unilateral with increased vertical vergences
40
Q

When is neuroimaging ordered for children with CN IV palsy?

A
  • bilateral
  • evidence of dorsal midbrain syndrome
  • other cranial nerves involved
41
Q

When should caution be used with monocular occlusion as a management option for CN IV Palsy?

A

Children- may develop amblyopia

42
Q

How can prism be used to manage CN IV palsy?

A

BD over the hyper (paretic) eye; can split prism between the two eyes

BD over hyper eye; BU over fellow eye

43
Q

Which type of CN IV Palsy would benefit the most from surgery?

A

traumatic

Wait at least 6 months for spontaneous improvement

allow time to see if blood/ edema will clear; relieve symptoms with occlusion therapy or prism in meantime

43
Q
A