CN - Chapter 6 - Neurotransmitter Systems Flashcards
cholinergic
Describing neurons or synapses that produce and release acetylcholine (ACh).
noradrenergic
Describing neurons or synapses that produce and release norepinephrine (NE).
glutamatergic
Describing neurons or synapses that produce and release glutamate (Glu).
GABAergic
Describing neurons or synapses that produce and release gamma-aminobutyric acid (GABA).
peptidergic
Describing neurons or synapses that produce and release peptide neurotransmitters.
immunocytochemistry
An anatomical method that uses antibodies to study the location of molecules within cells.
<i>in situ</i> hybridization
A method for localizing strands of messenger RNA (mRNA) within cells.
autoradiography
A method for visualizing sites of radioactive emissions in tissue sections.
microionophoresis
A method of applying drugs and neurotransmitters in very small quantities to cells.
receptor subtype
One of several receptors to which a neurotransmitter binds.
nicotinic ACh receptor
A class of acetylcholine-gated ion channels found in various locations, notably at the neuromuscular junction.
muscarinic ACh receptor
A subtype of acetylcholine receptor that is G-protein-coupled.
AMPA receptor
A subtype of glutamate receptor; a glutamate-gated ion channel that is permeable to Na+ and K+.
NMDA receptor
A subtype of glutamate receptor; a glutamate-gated ion channel that is permeable to Na+, K+, and Ca2+. Inward ionic current through the <i>N</i>-methyl--asparate receptor is voltage dependent because of a magnesium block at negative membrane potentials.