CMP/BMP Flashcards
Why is serum CO2 measured?
CO2 is a good estimate for serum bicarbonate levels because serum bicarb comprises about 95% total CO2 content.
Normal serum CO2 level?
20- 28 mmol/L (normal range varies widely depending on source)
What is the clinical significance of low CO2?
Low CO2 (i.e. low bicarb) indicates either metabolic acidosis or compensated respiratory alkalosis, though bicarb < 10 almost always signifies metabolic acidosis. (Comp for Resp alk will not drive bicarb that low)
What is an cation?
A positively charged molecule. It has net positive charge b/c is has more protons than electrons
What is an anion?
A molecule with a net negative charge. It has a negative charge b/c it has more electrons than protons
Which electrolyte is the most abundant anion in the extracellular fluid?
Normal chloride
102-110 mmol/L (per UUHac)
In difficult ti interpret acid base disorders, consider which electrolyte?
Chloride
Hyperchloremia may indicate:
Compensated respiratory alkalosis OR excessive bicarb loss 2/2 diarrhea, mineralcorticoid deficiency, renal tubular necrosis
Hypochloremia may indicate:
Metabolic alkalosis OR compensated respiratory acidosis, or excessive vomiting, mineralcorticoids, & salt losing renal diseases.