CMH Flashcards

1
Q

Fx del CMH

A

Fija fragmentos de péptidos patogenos o antiG propios para presentar a LT y generar IL

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2
Q

Fx del CMH

A

Fija fragmentos de péptidos patogenos o antiG propios para presentar a LT y generar IL

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3
Q

Características del CMH

A

Poligénico
Polimorfismo
Codominancia
Enlazamiento

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4
Q

En qué cel se expresa HLA2

A

Macrófago
CPA profesionales
CD
LB
Cel endoteliales si es inducida

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5
Q

Que fijan las HLa1

A

Péptidos de 9-11aa

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6
Q

Que fijan las HLa1

A

Péptidos de 9-11aa

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7
Q

Que fijan las HLA2?

A

Péptidos de 10-30aa

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8
Q

HLA QUE SE UBICA EN LA PARTE CENTROMERICA

A

HLA2

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9
Q

HLA QUE SE UBICA EN PARTE TELOMERICA

A

HLA1

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10
Q

Que componente del HLA PERMITEN EL RECONOCIMIENTO DE ANTIG

A

Residuos de alfa hélice

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11
Q

Por medio de que se une HLA a CD8?

A

Por región alfa 3

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12
Q

Fx de la b2 microglobulina

A

Estabilidad a moléculas

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13
Q

Amplificador de la presentación a antígénica

A

IFN GAMMA
IFN 1

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14
Q

Dominio el el cual el HLA SE UNE A PEPTIDOS

A

Región polimorfica

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15
Q

Región por la que HLAI se une a CD_

A

Región alfa 3
CD8

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16
Q

Región por la cual HLAII se une a CD_

A

Beta 2
CD4

17
Q

HLA SI/NO DISTINGUE ANTIG PROPIOS DE LOS EXTRAÑOS

A

No

18
Q

Marcan moléculas para su degradación

A

Ubiquitina