CM Flashcards

1
Q
  1. Total renal BLOOD flow
  2. Total renal PLASMA flow
A
  1. 1,200 ml/min
  2. 600-700 ml/min
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2
Q

renal threshold for glucose

A

160-180 mg/dl

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3
Q
  1. Regulates water reabsorption in dct and cd
  2. Dse under dis hormone
A
  1. ADH/Vasopressin
  2. DI (adh deficiency), SIADH (adh excess)

Hydraed = Dec. adh
Dehydrated = Inc. adh

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4
Q

Regulates **sodium ** reabsorption in dct

A

Aldosterone

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5
Q

Process

Angiotensinogen > renin > angio I > ace > angio II - effects?

A
  1. Inc. na and water reabsorption
  2. vasoconstriction (inc. blood flow)
  3. correct renal blood flow

JG cells - prod. renin
Macula densa - detects dec. in bp

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6
Q

Functions:
* regulates acid-base bal. thru hydrogen secretion (ammonium (nh4), dihydrogen phosphate (h2po4)
* eliminates waste prod not filtered by glomerulus

A

tubular secretion

renal tubular acidosis - failed prod of acid in urine due to inability to secrete hydrogen ions

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7
Q
  1. Evaluate glomerular filtration - able to remove filterable substance from blood
  2. Most common
  3. Gold std
  4. Marker - renal tubular function
A
  1. Clearance
  2. Creatinine
  3. Insulin
  4. Beta-microglobulin
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8
Q
  1. Detect and monitor kidney dse
  2. Dis mtd developed by
A
  1. eGFR
  2. cockgroft and gault

modification of diet in renal dse - Isotope dilution mass spectrophotometry (mdrd-idms) - reco. by National kidney dse education program

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9
Q
  1. Evaluate tubular reabsorption
    test:
  2. use number and density of particles in soln
  3. use number of particles in soln
A
  1. Concentration
  2. SG
  3. Osmolality (preferred)

Obsolete
1. Fishberg
2. Mosenthal

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10
Q

Test for both secretion and renal blood flow - most commonly use; reference mtd

A

p-aminohippuric acid (pah)

Obsolete
* penlsulfonpthalein (psp)

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11
Q
  1. First illustrated medical book printed - urine wheel
  2. Blood
  3. Yellow bile
  4. Phlegm
  5. Black bile
A
  1. Johannes de kethams fasciculus medicinae 1491
  2. sanguineous
  3. choleric
  4. phlegmatic
  5. melancholic
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12
Q

Albuminuria - boiling water

A

Frederik dekkers

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13
Q

Uroscopy, Sputum exam

A

Hippocrates

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14
Q

Book - pisse prophets

A

thomas bryant

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15
Q

urine sediment

A

thomas addis

addis count

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16
Q

UA - doctor’s routine exam

A

richard bright

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17
Q

urochrome

A

ludwig thudichum

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18
Q

CFS

A

domenico cotugno

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19
Q

phenylketonuria

A

ivan folling

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20
Q

alkaptonuria

A

archibald garrod

21
Q

Orthostatic/cylic proteinuria

A

frederich willian pavy

22
Q

cystine calculi

A

willian wollaston

23
Q
  1. Organic compound of urine
  2. Inorganic
A
  1. Urea > Crea
  2. Cl > Na > K > NaCl (principal salt)

60g = 24 hrs

24
Q

Collection

Cytology
1. Ideal
2. Preferred

A
  1. Random
  2. 1st morning
25
Q

Collection

Diabetes
1. Screen/Monitor
2. Diagnosis

A
  1. 2hr post prandial
  2. Fractional specimen (2 - series)
26
Q

Collection

Glucose
1. Determination
2. Screen

A
  1. 2nd morning
  2. 2hr post prandial
27
Q

Collection

Prostatic infection

A
  1. 3 glass tech
  2. Stamey-Meares (4 glass)

Prostatitis

28
Q

Collection

Orthostatic proteinuria

A

1st morning

29
Q

addis ct

A

12 hr urine

30
Q

Nitrite/1st morning detr.

A

4 hrs

Urine stayed 4 hrs before voiding

31
Q

Urobilinogen

A

afternoon 2-4pm

32
Q

adultered specimen

A

pH >9
SG < 1.005

Blueing agent -added to toilet water, avoid adulteration

33
Q

Least affected in unpreserved urine

A

Protein

Dec rbc/wbc - disintigrate in dilute alkaline urine

34
Q

Preservative

  • Precipitates amorphous phosphates and urates
  • For ua, culture (inhibits bacterial growth 24hrs)
A

Refrigeration

Gray C & S tube - 48hrs inhibit bacterial growth

35
Q

Preservative

  • Preserves protein
  • Bacteriostatic
  • 5-hiaa
  • Culture transport
A

Boric acid

36
Q

Sediment preservative thus, addis ct

A

Formalin

37
Q
  • Floats and clings preservative
  • Best all around preservative
A

Toluene

38
Q

Preservative

  1. Prevents glycolysis but it inhibits strips
  2. Alternative
A
  1. Sodium flouride
  2. Sodium benzoate

drug analysis

39
Q

Refrigeration is not possible

A

Tablet

40
Q

Preservative - odor change

A

Phenol

41
Q

Preserative

  • Preserves cellular elements
  • For cytology studies
A

Saccomanno fixative

50% ethanol + 2% carbowax

42
Q

Brown black urine

A
  1. Methemoglobin
  2. Homogentisic acid - alkaptunuria
  3. melanin - air exposure
  4. fava beans - cola
43
Q

purple urine

A

indican - kleb. and providencia

44
Q

green urine

A
  • pseudomonas
  • phenol
45
Q

blue green urine

A
  • phenol
  • blue diaper syndrome - hartnup dse
46
Q
  1. tea colored urine w/ yellow foam
  2. orange, viscous w/ yellow foam
  3. organge yellow no yellow foam
A
  1. bilirubin
  2. phenazopyridine
  3. urobilin
47
Q

Soluble w/ heat

Acidic

A
  • Amorphose urates
  • uric acid
48
Q

Soluble - Dilute acetic acid

Alkaline

A
  • rbc
  • amorphose phosphates
  • carbs

Insoluble
* livings: bacteria, yeast, spermatozoa
* wbc