CM Flashcards
- Total renal BLOOD flow
- Total renal PLASMA flow
- 1,200 ml/min
- 600-700 ml/min
renal threshold for glucose
160-180 mg/dl
- Regulates water reabsorption in dct and cd
- Dse under dis hormone
- ADH/Vasopressin
- DI (adh deficiency), SIADH (adh excess)
Hydraed = Dec. adh
Dehydrated = Inc. adh
Regulates **sodium ** reabsorption in dct
Aldosterone
Process
Angiotensinogen > renin > angio I > ace > angio II - effects?
- Inc. na and water reabsorption
- vasoconstriction (inc. blood flow)
- correct renal blood flow
JG cells - prod. renin
Macula densa - detects dec. in bp
Functions:
* regulates acid-base bal. thru hydrogen secretion (ammonium (nh4), dihydrogen phosphate (h2po4)
* eliminates waste prod not filtered by glomerulus
tubular secretion
renal tubular acidosis - failed prod of acid in urine due to inability to secrete hydrogen ions
- Evaluate glomerular filtration - able to remove filterable substance from blood
- Most common
- Gold std
- Marker - renal tubular function
- Clearance
- Creatinine
- Insulin
- Beta-microglobulin
- Detect and monitor kidney dse
- Dis mtd developed by
- eGFR
- cockgroft and gault
modification of diet in renal dse - Isotope dilution mass spectrophotometry (mdrd-idms) - reco. by National kidney dse education program
- Evaluate tubular reabsorption
test: - use number and density of particles in soln
- use number of particles in soln
- Concentration
- SG
- Osmolality (preferred)
Obsolete
1. Fishberg
2. Mosenthal
Test for both secretion and renal blood flow - most commonly use; reference mtd
p-aminohippuric acid (pah)
Obsolete
* penlsulfonpthalein (psp)
- First illustrated medical book printed - urine wheel
- Blood
- Yellow bile
- Phlegm
- Black bile
- Johannes de kethams fasciculus medicinae 1491
- sanguineous
- choleric
- phlegmatic
- melancholic
Albuminuria - boiling water
Frederik dekkers
Uroscopy, Sputum exam
Hippocrates
Book - pisse prophets
thomas bryant
urine sediment
thomas addis
addis count
UA - doctor’s routine exam
richard bright
urochrome
ludwig thudichum
CFS
domenico cotugno
phenylketonuria
ivan folling