CLTM - Board Prep Flashcards
CLTM, Long Term Monitoring, EEG, Epilepsy, Surgery, ECoG, grid electrodes, ambulatory EEG, EMU
What does OSHA stand for?
Occupational Safety & Health Administration

What is OSHA’s function?
- Prevent wrong-site surgery
- Protect Patient Health Information
- Insure an environment of patient safety
- Insures an environment of safety for all staff
Insures an environment of safety for all staff

What does CMS stand for?
Centers for Medicare & Medicaid Services

What does CMS administer?
- Medicare & Medicaid
- Medicare, Medicaid & HIPPA
- Affordable Care Act
- Joint Commission Accredidation
Medicare, Medicaid & HIPPA

Dysgeusia
Distortion of sense of taste.

Dystonia
- Sustained muscle contractions
- twisting
- repetitive movements
- abnormal posturing.

Ataxia
Loss of muscle coordination & movement.
causes gait disturbance.

Cataplexy
Sudden loss of consciousness triggered by laughing, crying, or fear.
EEG with Cataplexy
Normal
Narcolepsy
The brain’s inability to regulate sleep-wake cycles.
EEG with narcolepsy
Early onset REM during sleep
Wallenbergs Syndrome
Injury to the lateral medulla, resulting in tissue ischemia & necrosis, with sensory defecits in:
- Trunk & extremities on contralateral side of Injury.
- Face & cranial nerves on the ipsilateral side of the injury.
Dysphagia
Difficulty Swallowing
Vertigo
Dizziness
Nystagmus
Involuntary Rhythmic movement of the eye.
(vertically or horizontally)

Dysarthria
Slurred Speech
Ptosis
Drooping eyelid

Horners Syndrome
The unilateral combination of:
- drooping eyelid (ptosis)
- constricted pupil (miosis)
- decreased sweating (anhidrosis)
- eye redness

Cortical Dysplasia
- Absence Seizures
- Keppra
- Intractable Seizures
- Wests Syndrome
Intractable Seizures
Describe Hyperlexia
Fascination with letters or numbers & advanced reading ability.
Hyperpraphia
Overwhelming urge to write.
Associated with temporal lobe epilepsy.
Hippocampal Sclerosis
Neuronal cell loss & gliosis in hippocampus
Specifically the CA-1 (Cornu Ammonis Area 1) & subiculum.
How do you test for Hippocampal sclerosis
MRI
Hippocampal Sclerosis
- Neocortex of Temporal Lobe
- Globus Pallidus
- Mesial Temporal Lobe Epilepsy
- Supplemental Motor Cortex
Mesial Temporal Lobe Epilepsy
Neocortex of Temporal Lobe
- Medial Temporal Lobe Epilepsy
- Lateral Temporal Lobe Epilepsy
- Mesial Temporal Lobe Epilepsy
- Longitudinal Temporal Lobe Epilepsy
Lateral Temporal Lobe Epilepsy
Generic Dilantin®
Phenytoin
Generic Depakote®
Valproic Acid or Valproate
Side effect of Phenytoin (Dilantin®) withdrawl
Status Epilepticus
Drug of choice for Infantile Spasms
ACTH
Adreno-Cortico-Tropic Hormone
Adrenocorticotropic Hormone
Drug of choice for Juvenile Myoclonic Epilepsy
Depakote®
Valproic Acid / Valproate
Drug of choice for Juvenile Absence Seizures
Ethosuximide / Zarontin®
Drug of choice for Lennox-Gastaut
Depakote® / Valproic Acid / Valproate
Define ACTH
Adreno-Cortico-Tropic Hormone
Adrenocorticotropic Hormone
Drug of Choice for Complex Partial Epilepsy
Keppra® / Levetiracatam
Define Seizure
Sudden involuntary time-limited alteration in behavior, with change in motor activity, autonomic function, consciousness or sensation, accompanied by abnormal electrical discharge in the brain
Define Epilepsy
- more than 2 Seizures
- Nerve cell activity in your brain is disrupted, causing abnormal behavior, sensations, or loss of consciousnes.
Define Seizure Semiology
- Clinical Manifestations
- Seizure Description
Clinical manifestation of Gelastic Seizures
Laughing
Clinical manifestation for Dacrystic Seizures
Crying
Describe typical ictal progression for partial and convulsive seizures.
Ictal discharge begins with low-voltage fast activity and becomes slower with higher amplitude.
Most common co-morbidity in Gelastic & Dacrystic Seizures
Hypothalamic Hamartoma

Define Todd’s Paralysis
- Partial or complete paralysis following seizure
- Unilateral & may involve speech & vision
- Duration: 30 min - 36 hrs (avg 15hrs)
Seizure begins with a tingling sensation or motor movement in the fingers, then affects movement in the hand and moves on to more proximal areas on the same side of the body with progression to the contralateral side of the body as the event crosses over the corpus callosum.
Name this seizure
Jacksonian March
Jacksonian March:
- Generalized Seizure
- Primary focal, secondarily generalized.
- Complex partial seizure
- Simple partial seizure
Simple partial seizure
Hypsarrhythmia (in pediatrics)
- Complex Partial Seizure
- Hypnogogic Hypersynchrony
- Infantile Spasms
- Tonic Clonic Seizures

Infantile Spasms

Hypsarrythmia (in Adults)
- Lennox Gastaut
- Rasmussens Encephalitis
- Juvenile Myoclonic Epilepsy
- West Syndrome

West Syndrome

Abdominal Epilepsy (Stomach Pain)
- Frontal Lobe
- Temporal Lobe
- Parietal Lobe
- Occipital Lobe
Temporal Lobe
Atonic Seizures
- Olfactory Aura
- Drop Attacks
- Infantile Seizures
- Epileptic Syndrome
Drop Attacks
(Drop Seizures)
Atonic Seizures are also referred to as:
- Affective Epilepsy
- Ataxic Epilepsy
- Akinetic Seizures
- Aphasic Seizures
Akinetic Seizures
Treatment for Intractable Atonic Seizures
Corpus Callosotomy
Corpus callosum is severed to stop seizures.
Intractable Epilepsy (in childhood)
- Febrile Seizures
- Paraneoplastic Neurologic Syndrome
- Lennox Gaustox Syndrome
- Benign Rolandic Epilepsy
Lennox Gaustox Syndrome
Intractable epilepsy (in Infancy)
- Complex Partial
- Absence
- Jacksonian
- Infantile Spasms
Infantile Spasms
Seizure involving visual hallucination of un-formed images (flashing lights, colors)
- Frontal Lobe
- Temporal Lobe
- Parietal Lobe
- Occipital Lobe
Occipital Lobe
Seizure involving bilateral tonic posturing
- Frontal Lobe
- Temporal Lobe
- Parietal Lobe
- Occipital Lobe
Frontal Lobe
Jacksonian March originating in left hand and fingers
- Onset in left temporal lobe (T3)
- Onset in right temporal lobe (T4)
- Onset in left frontal lobe (C3)
- Onset in right frontal lobe (C4)
Onset in right frontal lobe (C4)
Dysgeusia
- Memory
- Taste
- Déjà vu
- Smell
Taste
Seizure or aura involves dysgeusia
- Globus Pallidus
- Amydala
- Insula
- Hippocampus

Insula

Seizure or aura involves formed images or hallucinations
- Globus Pallidus
- Amydala
- Insula
- Amygdala\Hippocampus
Amygdala \ Hippocampus

Seizure or aura involves formed images or hallucinations
- Posterior temporal lobe
- Anterior temporal lobe
- Occipital Lobe
- Frontal lobe

Posterior temporal lobe

Seizure or aura involves tingling sensation of right hand\ arm
- Anterior Parietal lobe-right
- Anterior Parietal lobe-left
- Posterior Frontal lobe-right
- Posterior Frontal lobe-left

Anterior Parietal lobe - left (Contralateral)

Seizure or aura involves right eye deviation and head deviation with posturing
- Anterior Temporal lobe-left
- Anterior Parietal lobe-left
- Posterior Frontal lobe-right
- Posterior Frontal lobe-left

Posterior Frontal lobe - left

Seizure or aura involves epigastric sensations & salivation
- Insular-orbital frontal cortex
- Hippocampus
- Limbic system
- Mid-temporal lobe
Insula-orbitofrontal cortex

Seizure or aura involves epigastric sensations & salivation
- Insular-orbital frontal cortex
- Hippocampus
- Amygdala-opercular region
- Mesial aspect of the temporal lobe
Amygdala-opercular region

Seizure aura involving olfactory (Smell) hallucinations
- Insular-orbital frontal cortex
- Hippocampus
- Prefrontal Lobe
- Anteromedial temporal lobe
Anteromedial temporal lobe

Seizure aura involves olfactory (Smell) hallucinations
- Insular-orbital frontal cortex
- Anterior Parietal lobe
- Amygdala-opecular region
- Occipital lobe
Amygdala-opecular region
Non-purposeful stereotyped and repetitive behaviors such as picking, fumbling, patting aura , lip smacking, chewing and swallowing:
- Automatism
- Aura
- Dysplasia
- Apraxia
Automatism
What does SUDEP stand for
Sudden Unexpected Death in Epilepsy
What are the 6 criteria for diagnosis of SUDEP
The 6 criteria for SUDEP
- Suffered from Epilepsy (unprovoked seizures)
- They were in reasonable state of health
- Occurred suddenly
- During normal activities & circumstances
- No obvious cause of death found
- Not a direct cause of seizure or status epilepticus
Hippocampal Sclerosis is the most common type of neuropathological damage seen in individuals with:
- Absence Seizures
- Temporal Lobe Epilepsy
- Grand Mal Seizures
- Jacksonian March
Temporal Lobe Epilepsy
Which of the following is associated with** Hippocampal Sclerosis?**
a. Simple Partial Seizures
b. Complex Partial Seizures
c. Generalized Seizures
d. Status Epilepticus
Complex Partial Seizures
Age of onset & peak age for Absence Seizures
- *Onset**: 3-12 yrs
- *Peak**: 6-7 yrs
Absence 3.6.7.12
Age of onset for Juvenile Myoclonic Epilepsy
Onset: 12-18 yrs
Juvenile 12.18
Age of onset & peak age for Benign Rolandic Epilepsy
- *Onset**: 2-13 yrs
- *Peak**: 9-10 yrs
Rolandic 2.9.10.13
Age of onset & peak age for Benign Occipital Epilepsy
- *Onset**: 15 months - 15 yrs
- *Peak**: 4-8 yrs
Occipital 15.4.8.15
Age of onset & peak age for Wests Syndrome (Infantile Spasms)
- *Onset**: < 1yr
- *Peak**: 3-7 mo.
Infant/West 0.3.7.1
Age of onset & peak age for Lennox Gastaut
- *Onset**: 1-8 yrs
- *Peak**: 3-5 yrs
Lennox 1.3.5.8
Age of onset for Landau Kleffner
Onset: 2-12 yrs
Landau 2.12
Name the two **epilepsy syndromes** that **have** a cognitive delay (**mental retardation**) as a **characteristic**
- West Syndrome (Infantile Spasms)
- Lennox-Gastaut
Name the epilepsy syndrome that is characterized by speech arrest
Landau-Kleffner
Which of the following is typically associated with non-epileptic seizures:
- Episode lasting < two minutes
- Episode lasting > two minutes
- Episode of tongue biting
- Episode of tongue thrusting
Episode lasting over two minutes
Which of the following is typically associated with non-epileptic seizures:
- Blinking
- Lip smacking
- Side to side head movements
- Eye deviation to the right
Side to side head movements
Which of the following is typically associated with non-epileptic seizures:
- Teeth breakage
- Severe tongue biting
- Biting the inside of the mouth
- Biting the tip of the tongue
Biting the tip of the tongue
Which of the following is typically associated with non-epileptic seizures:
a. Bicycling actions of all limbs
b. Pelvic thrusting & Weeping
c. Picking or pulling at clothing
d. Masturbation
Pelvic thrusting & Weeping
Which of the following is typically associated with non-epileptic seizures:
- Blinking
- Staring
- Eye deviation
- Eyes dosed
Eyes closed
Brainstem Lesion:
- Spindle Coma
- Beta Coma
- Alpha Coma
- Theta Coma
Alpha Coma

Mesencephalic Lesion:
- Spindle Coma
- Beta Coma
- Alpha Coma
- Theta Coma
Spindle Coma
Locked-in Syndrome:
- Spindle Coma
- Beta Coma
- Alpha Coma
- Theta Coma
Alpha Coma
Alpha Coma Prognosis
- Poor
- Good
- Great
- Unknown
Poor
Spindle Coma Prognosis
- Poor
- Good
- Great
- Unknown
Good
Beta Coma Prognosis
- Poor
- Good
- Great
- Unknown
Good
Describe the reactivity of Alpha Coma
Non-reactive (EEG does not change with painful stimuli)
Name the coma type which involves paralysis of the lower cranial nerves.
Alpha Coma
Level of consciousness with Alpha Coma
Awake & Alert
S.I.R.P.I.Ds
- Slow irregular rhythmic polyphasic epileptiform discharges of sleep
- Sharp intermittent rhythmic polyphasic epileptiform discharges
- Stimulus Induced Rhythmic or Periodic or Ictal Discharges
- Spikes In REM Presenting Entirely with Delta
Stimulus Induced Rhythmic or Periodic or Ictal Discharges
S.I.R.P.I.Ds
- REM Sleep disorder
- Acute Brain Injury
- Brain Stem Infarction
- Brain Tumor
Acute Brain Injury
Define Long-Term Potentiation (LTP)
- Lasting enhancement in signal transmission between neurons from synchronus stimulation.
- Phenomena of synaptic plasticity, & ability of chemical synapses to change their strength.
- Widely considered one of the cellular mechanisms that controll learning & memory.
Hippocampus
- Limbic System
- Reticular Formation
- Lymphatic System
- Cortical System
Limbic System
4 functions of the Hippocampus
- Short term memory
- Long Term Memory
- Spatial navigation
- Inhibition
Long Term Potentiation
- Neural Matrix
- Neural Tissue
- Neural Network
- Neural Plasticity
Neural Plasticity
Define Neural Plasticity
Changes in neural pathways & synapses from changes in behavior, environment or bodily injury.
Function of the Parahippocampal Gyrus

Memory Encoding & Retrieval

Functions of the Amygdala
Memory & Emotion
Resting Membrane Potential of a neuron
a. -70 µV
b. -70 mV
c. -70 mA
d. -70 µA
-70 mV (mV=Millivolts)
EPSPs & IPSPs
- Cortical Pyramidal Cells
- Frontal Lobe
- Neocortex
- Deep Brain Structures
Cortical Pyramidal Cells
Excitatory postsynaptic potential & Inhibitory postsynaptic potential

Define HIPAA
Health Insurance Portability & Accountability Act
Function of HIPAA
Protects a patient’s oral, written or electronic health information (PHI) from being disclosed.
HIPAA requires that all medical record sharing to be preceded by:
- Oral or written authorization from patient
- Oral or written authorization from patient or patients family
- Written authorization from patient
- Written authorization from patient or the patients family
Written authorization from patient
Preferred stimulator type for direct cortical stimulation in epilepsy surgery
Bipolar, constant-current
Preferred intensity range of stimulation for direct cortical stimulation in epilepsy surgery
0-20 mA (mA=milliamps)
Describe stimulation period for direct cortical stimulation in epilepsy surgery
1-10 seconds
Define the threshold range typically used to define function over the motor cortex for direct cortical stimulation in epilepsy surgery
2-5 mA (mA=milliamps)
Define the threshold range typically used to define function over the language cortex for direct cortical stimulation in epilepsy surgery
8-15 mA (mA=milliamps)
Define the EEG Sensitivity recommended for recording from grid electrodes over the exposed cortex for direct cortical stimulation in epilepsy surgery
50-100 µV (µV=microvolts)
Amplifier bandpass for Motor Mapping
1 - 30 Hz to 250 - 1,500 Hz (-3dB)
Analysis time for Motor Mapping
50 msec
(milliseconds or ms)
Rate, Duration & Intensity for Motor Mapping
- Rate: 3-5 /sec (Per second)
- Duration: 100-300 µsec (microseconds)
- Intensity: 30-60 mA (milliamps)
Amplitude range of **Motor Mapping **responses
20 - 500 µV (microvolts)
GOLD STANDARD in assessing patients for epilepsy surgery
MRI
Phase One Epilepsy Monitoring Unit:
- Surface electrodes, Expanded international 10-10 System, Sphenoidal, Foreman Ovale, NP Electrodes
- Intracranial electrodes
- lntracranial electrodes & Neurosurgical resection
- Intracranial electrodes & MEG Monitoring
Surface electrodes, Expanded international 10-10 System, Sphenoidal, Foreman Ovale, NP Electrodes
Phase two Epilepsy Monitoring Unit:
- Surface electrodes, Expanded international 10-10 System, Sphenoidal, Foreman Ovale, NP Electrodes
- Intracranial electrodes
- lntracranial electrodes & Neurosurgical resection
- Intracranial electrodes & MEG Monitoring
Intracranial electrodes
Phase two Epilepsy Monitoring Unit:
- Surface electrodes, Expanded international 10-10 System, Sphenoidal, Foreman Ovale, NP Electrodes
- Intracranial electrodes
- lntracranial electrodes & Neurosurgical resection
- Intracranial electrodes & MEG Monitoring
lntracranial electrodes & Neurosurgical resection
WADA
- Widespread Anti-epileptic Drug Analysis
- Sodium Amobarbital Test
- Seizure Focus
- Seizure Classificiation
Sodium Amobarbital Test
WADA
- Language & Short Term Memory
- Language & Long Term Memory
- Speech & Short Term Memory
- Speech and Long Term Memory
Language & Short Term Memory
WADA
- Sensori-motor Mapping
- After Discharge
- Epileptic Focus
- Hemispheric Dominance
Hemispheric Dominance
WADA
a. Pre-surgical assessment for epilepsy
b. Bedside monitoring for NES
c. Diagnosis of Epilepsy
d. Classification of Epilepsy
Pre-surgical assessment for epilepsy
WADA is performed in
- Surgery
- Bedside monitoring
- lnterventional Radiology
- EEG Department
lnterventional Radiology
WADA: Medication used
- Pentobarbital
- Phenobarbital
- Propofol
- Sodium Amobarbital
Sodium Amobarbital
A WADA is performed in conjunction with:
- MRI
- X-Ray
- Flouroscopy
- PET Scan
Flouroscopy
During WADA testing, imaging is used to:
- Visualize the catheter and target vessel
- Visualize the epileptic focus
- Determine if the medication is needed
- Determine if the medication is necessary
Visualize the catheter and target vessel
During WADA testing the medication is injected into:
- Femoral Artery through a femoral catheter
- Carotid Artery through a femoral catheter
- Middle Cerebral Artery through a carotid catheter
- Anterior Cerebral Artery through a carotid Catheter
Carotid Artery through a femoral catheter
During WADA medication injection results in:
- EEG epileptiform activity ipsilateral to side of injection & functional loss contralateral to injection side
- EEG epileptiform activity contralateral to side of injection I functional toss ipsilateral to injection side
- EEG Slowing ispitateral to side of injection and functional loss contralateral to injection side
- EEG Slowing contralateral to side of injection and functional loss ipsilateral to injection side
- *EEG Slowing ispitateral** to side of injection and
- *functional loss contralateral** to injection side
During WADA recall testing is performed using
- Words & Pictures
- Names & Faces
- Previous EEG
- Hemiparesis
Words & Pictures

Short term memory
- Mammillary Body & Corpus Collosum
- Mammillary Body & Pre-frontal Gyrus
- Hippocampus & Globus Pallid us
- Hippocampus & Amygdala
Hippocampus & Amygdala

Image Shows:
- Left Hippocampal Sclerosis
- Right Hippocampal Sclerosis
- Left Cortical Dysplagia
- Right Cortical Dysplagia

Right Hippocampal Sclerosis

What type of image is this?

MRI

Image Shows:
- Left Hippocampal Sclerosis
- Right Hippocampal Sclerosis
- Left Cortical Dysplagia
- Right Cortical Dysplagia

Left Cortical Dysplagia

What does an Functional MRI (fMRI) measure?
Measures hemodynamic response of** neural activity**.
Can lateralize, but can’t localize, language & motor function.
What does a Magnetic Resonance Spectroscopy (MRS) measure
Measures the levels of different metabolites in body tissues. Lateralizes hippocampal sclerosis in some patients
What is Stealth MRI
Combines 3-D MRI & CT Scans to recreate the placement of grids

What is a PET Scan & what does it measure
Positron Emission Tomography (PET) scan uses a radioactive tracer to see disease in the body, which reveals the structure & blood flow to & from organs. Shows how organs and tissues are working (glucose metabolism)

Define SPECT
Single Photon Emission Computed Tomography
What does SPECT measure?
Used to image directly the regional increase in cerebral blood flow that occurs during an epileptic seizure, thereby imaging the epileptic focus
Describe the window needed to inject the radioactive dye (tracer) for SPECT scan?
The injection is given during or following the seizure & the scan needs to be taken within 6 hours
What is MEG and what does it measure?
- Magnetoencephalography provides more accurate ability to estimate the dipole source, which provides noninvasive information on the normal or abnormal function of discrete cortical areas.
- This is used for mapping the location of somatosensory and motor function during pre-surgical planning
- Mapping of language and other cognitive functions is under development
Neonatal Continuous EEG protocols are applicable for which age patient?
High risk neonates
Post-menstrual age less than 48 weeks
Which of the following is characteristic of neonatal seizures:
- Generalized tonic clonic
- Paroxysmal increases in heart rate or blood pressure
- lateralized arm or leg movements
- Facial twitching
Paroxysmal increases in heart rate or blood pressure
Name the 6 stereotypical manifestations of neonatal seizure
- **Focal Tonic **or clonic movements
- Intermittent forced, conjugate, horizontal gaze deviation
- Myoclonus
- Generalized tonic posturing
- Brainstem release phenomena, such as oral-motor stereotypes, reciprocal swimming movements or the upper extremities or bicycling movements of the legs
- Autonomic paroxysms such as unexplained apnea, pallor, flushing, tearing, and cyclic periods of tachycardia or elevated blood pressure
Define the recommended extracerebral monitoring channels for Neonates
- Electrocardiogram (ECG)
- Electrooculogram (EOG)
- Respiratory Channels
- Electromyography (EMG)
In which of the following conditions would you most expect seizures to occur with neonatal population (requiring EEG monitoring)
- Arterial ischemic stroke
- Hypoxic Ischemic encephalopathy
- Tuberous Sclerosis
- Metabolic encephalopathy
Tuberous Sclerosis
(A genetic disorder that causes non-malignant tumors to form in many different organs, primarily in the brain, eyes, heart, kidney, skin and lungs.)
In which of the following conditions would you most expect seizures to occur with neonatal population (requiring EEG monitoring)
- Birth anoxia
- Cerebral dysgenesis
- Sinovenous thrombosis
- Meningeoencephalitis
Cerebral Dysgenesis
(improper brain development in utero)
Name 2 medications used in the neonatal population for induced Burst Suppression
- Pentobarbital
- Midazolam (versed)
Define Gestational Age
The time between the onset of the mother’s last menstrual period & the date of birth (In weeks)
Define Conceptional Age
Gestational age plus the time since birth (In weeks)
What is the recommended recording time for neonatal EEG?
> 60 Minutes (1 Hr)
What is the first recordable EEG pattern in neonates?
Trace Discontinu

Trace Discontinu:
- Active Sleep
- Quiet Sleep
- All states of wake & sleep
- Abnormal pattern

All states of wake & sleep

Trace Discontinu:
- 24-26 Weeks CA
- 24-26 Weeks GA
- 27-28 Weeks CA
- 27-28 Weeks GA
24-26 Weeks CA (Conceptional Age)
Trace Discontinu:
- Reactive to stimulation
- Non-reactive to stimulation
- State dependent reactive background
- Brief reactivity with generalized distribution
Non-reactive to stimulation
When is background reactivity first seen in neonates?
- 29-30 weeks CA
- 31-33 weeks CA
- 34-35 weeks CA
- 38-40 Weeks CA
34-35 weeks CA (Conceptional Age)
Normal sharp transients in the neonatal population:
- Frontal
- Temporal
- Central
- Parietal
- Occipital
Frontal
Age at which EEG is synchronous in the neonatal population:
- 36 weeks CA
- 38 weeks CA
- 40 weeks CA
- 42 weeks CA
40 weeks CA (Conceptional Age)
Age at which Trace Alternant is first recorded in the neonatal population:
a. 29-30 weeks CA
b. 31-33 weeks CA
c. 34-35 weeks CA
d. 38-40 weeks CA
38-40 weeks CA (**Conceptional **Age)
Another name for Frontal sharp transients in the neonatal recording.
Enchoches Frontales
Frontal sharp transients:
- Asynchronous & Bilateral
- Synchronous & Bilateral
- Asynchronous and Lateralized
- Synchronous & Lateralized
Synchronous & Bilateral
At what age do Delta Brushes occur in the **neonatal **recording.
26-32 weeks CA (Conceptional Age)
At what age do Delta Brushes occur during REM (Active) sleep in the **neonatal **recording.
29-33 weeks CA (Conceptional Age)
At what age do Delta Brushes occur during non REM (Quiet) sleep in the neonatal recording.
33-38 **weeks CA (Conceptional **Age)
Name the 3 criteria associated with non-REM (Quiet) sleep.
- Regular Respiration
- Random Eye Movements
- Variable Muscle Tone
Name the 3 criteria associated with REM (Active)
sleep.
- Irregular respiration
- Rapid Eye Movements
- Decreased Muscle tone
When does the Trace Alternant pattern disappear in the neonatal EEG?
44 weeks
3-4 weeks post-term
Define Trace Alternant:
EEG pattern of sleeping newborns, characterized by bursts of slow waves, at times intermixed with sharp waves, and intervening periods of relative quiescence with extreme low amplitude activity.
In which sleep stage does Trace Alternant appear
Quiet Sleep (non REM)
Which sleep stage appears first in the neonate?
Active Sleep (REM)
At 27-34 weeks CA which sleep stage does the neonate spend most time in?
Active (REM)
At 27-34 weeks PMA, 40-45% is spent in active sleep, 25-30% in quiet sleep, and 30% in indeterminate sleep.
Beyond 35 weeks which sleep stage does the neonate spend most time in?
Active
Beyond 35 weeks PMA, infants spend 55·65% of the time in active sleep, 20% in quiet sleep and 10-15% in indeterminate sleep.
Sphenoidal, Foreman Ovale, Nasopharyngeal & T1 \ T2 Electrodes
- Invasive
- Mesial
- Medial
- Basal
Basal
Explain Sphenoidal Electrode Placement
- invasive & placed by physician
- Records from anterior tip of temporal lobe
- Introduced through nasal cannula into the temporal and masseter muscles, the between the zygoma and sigmoid notch of the mandible.
- Tip lies lateral to the foramen ovale at the greater wing of the sphenoid bone

Define Foreman Ovale Electrode Placement
- Record mesial temporal or frontal discharges
- Invasive with up to 4 leads along the wire Guide needle punctures the cheek 3cm lateral to the corner of the mouth
- Forman ovale & subarachnoid space are penetrated by the inducer & the electrode is inserted into the caudal end of the ambient cistern.

Define Nasopharyngeal Electrode Placement
- Record inferior temporal & frontal discharges
- Flexible wire with insulated 2mm gold tips, 30-35cm long.
- S-Shaped, inserted thru the nasopharynx (nostrils) and rotated outward to rest within 2cm of the anterior mesial aspect of the temporal lobe.
- Respiratory & motion (swallow) artifact a problem.
Define T1 & T2 Electrode Placement
Anterior Temporal Electrodes
One third the distance anterior from the external auditory canal and the outer canthus of the eye then up 1cm
Metal of choice for Subdural & Depth Electrodes
Comprised of Platinum (preferred), stainless steet or gold
5 Risks with Subdural & Depth Electrodes
- Hemorrhage
- Infection
- Reactive meningitis
- Edema
- Headache
Most significant risks with Subdural & Depth Electrodes
Infection
Disadvantage of Subdural & Depth Electrodes
Sampling rate errors (aliasing)
4 Advantages of Subdural & Depth Electrodes
- Excellent signal to noise ratio
- Low Impedance
- Unaffected by muscle or movement artifact
- By-pass high resistance skull
Which electrode is closest to the somatosensory reception region for the left hand

CP4

LTME is limited to:
- Critical Care Monitoring
- Intra-Operative Monitoring
- Sleep Analysis Setting
- Epileptic or suspected epileptic seizure disorder
Epileptic or suspected epileptic seizure disorder
In LTME, The term “monitoring” implies what?
- Real time physician interpretation is needed
- No real time analysis of the data
- Technologist Interpretation
- Neurologist Interpretation
No real time analysis of the data
Sphenoidal electrodes record from?
- Mesial or anterior aspects of the temporal lobe in the area of the foreman ovale
- Medial temporal lobe in the area of the mandibular notch
- Hippocampus &Amygdala
- Limbic Structures
Mesial or anterior aspects of the temporal lobe in the area of the foreman ovale
During an ECOG, What is the indicated activity

Cortical Stimulation artifact

During an ECOG, What is the indicated activity

After Discharges

Sphenoidal recording electrodes:
- Nasopharyngeal Electrode
- Braided stainless steel wire, insulated except to the tip
- Platinum or stainless steel disks
- Platinum hook-wire electrodes
Braided stainless steel wire, insulated except to the tip
Which of the following electrodes should not be used in LTM:
- Sphenoidal
- Basal extracranial
- Nasopharyngeal
- Foreman ovale
Nasopharyngeal
Epidural & Subdural Electrodes
- Metal disk
- Stainless steel wire, insulated except at the tip
- Nasophyaryngeal
- Platinum or stainless steel disks embedded in soft silastic
Platinum or stainless steel disks embedded in soft silastic
Epidural & Subdural Electrode placement
- Epidural or subdural; over the cerebral cortex
- Mesial aspect of the temporal lobe
- Nasoethmoidal
- Supraoptic
Epidural or subdural; over the cerebral cortex
Method of placement for Subdural Electrodes:
- Braided stainless steel wire placed by a physician
- Through a burr hole after open craniotomy
- Subdermal placement by a physician
- Subdermal by a qualified technologist
Through a burr hole after open craniotomy
Intracranial or depth electrodes
- Platinum or stainless steel wire insulated to the tip
- Platinum disks embedded in soft silastic
- Pliable metal inserted into the nasal canal
- Stainless steel or MRI compatible nichrome
Stainless steel or MRI compatible nichrome
Foreman Ovale Electrodes
- Surface of the brain placed after open craniotomy
- Mesial temporal structures placed in the ambient cistern
- Pliable metal inserted into the nasal canal
- Mesial temporal stuctures placed in the zygomatic arch
Mesial temporal structures placed in the ambient cistern
Which of the following is best for recording mesial temporal EEG discharges best
- Foreman Ovale
- Nasopharyngeal
- Sphenoidal
- Nasoethmoidal
Foreman Ovale
LTME recommended low frequency response setting (low frequency filter)?
0.5 Hz or Lower
LTME recommended High frequency response setting (high frequency filter)?
70 Hz or Higher
LTME recommended Noise level of the amplifiers?
1 µV rms
or
1 (microvolt) (root mean squared)
LTME recommended Input Impedance of the amplifiers?
(At least) 1 M ohm
1 million ohms
LTME recommended Common Mode Rejection?
60 dB
LTME recommended Dynamic Range?
(At least) 40 dB
LTME recommended minimum recording/storage time with video?
Recording & Storage: 24 hours
(32-64 channels or 128 channels if needed)
LTME recommended minimum retrieval/review storage time with video?
30 gigabytes or 24 hrs of Video\EEG
What is the main/major objective of LTME:
- Classification of seizures
- Identify Non-epileptic seizures
- Correlation of behavior with EEG findings
- Identify non-convulsive status epilepticus
Correlation of behavior with EEG findings
Types of behavioral monitoring
- Clinical description, Mental Alerting, Level of Awareness testing
- Self reporting, Observer reporting, Video Recording
- Event push button, EEG comments, Video Recording
- Test word, math problems, technologist comments
Self reporting, Observer reporting, Video Recording
LTME recommended ictal event monitoring:
- Eye movement EMG & Cognitive Tasks
- EEG comments & Clinical description
- Event push button & level of awareness
- Test word & math problems
Eye movement EMG & Cognitive Tasks
LTME recommended cognitive disturbance documentation:
- Call patient name & document response
- Clinical signs observed or no clinical signs observed
- Reaction time tasks with stimulus & response times recorded on an event marker channel
- Test word of color or simple word: Red, Blue, Cat, Dog
Reaction time tasks with stimulus & response times recorded on an event marker channel
LTME recommended Ictal event testing: Name (4)
G.L.A.M.
- Gross Motor Function
- Language
- Awareness
- Memory
LTME recommended color perceived optical resolution of display monitor.
250 Line Pairs
LTME recommended optimal pixel standards of display monitor.
1600 X 1200 pixels
LTME recommended screen diagonal size of display monitor .
20 inches or more
LTME recommended archive of events should include what period of time before and after events?
2mm Along with a log of contents of event
LTME recommended electrode insertion for Sphenoidals.
- Inserted bilaterally below the zygomatic arches, 3-4 mm deep
- In the direction of the foramen ovale
- By a qualified physician
LTME recommended impedance measurement with epidural, subdural, intracerebral & foreman ovale electrodes.
- In the range of 10 nA
- 1,000 times less than disk electrodes
LTME recommended number of channels for standard recording (non pre-surgical)
8-12 channels
LTME recommended number of channels for pre-surgical recording
- *32-64 channels recommended**
- *Minimum of 16** channels
LTME recommended number of channels for ambulatory.
8 channels
LTME recommended number of channels for diagnosis of nonepileptic seizures.
8 channels
LTME recommended number of channels for classification and characterization of epileptic events.
18 channels
- 16 EEG
- 1 EOG
- 1 EKG
Eye movements, blinking, muscle tension, ECG, respiration, sweating, tremor, tooth brushing and glossokenetic are examples of what type of artifact?
- Instrumental
- Mechanical
- External
- Biological
Biological
Most common biological artifact seen with Sphenoidal electrodes
Pulse
How often should the ongoing status of the EEG recording be checked?
At LEAST once a day
Name the pattern seen in 1 year old child with cognitive delay & frequent seizures

Hypsarythmia

Name this pattern seen in a 5 yr old child with HX of staring spells

3 per sec Spike & Wave

Two patient identifiers are required prior to delivering care. Examples are:
- Hospital ID Bracelet & Patient Name
- Medical Record # & Birth date
- Patient name & Birth date
- Birthdate & Hospital ID Bracelet
Patient name & Birth date
Medical phone orders require:
- Confirmation number
- Read Back of order
- Return call confirming order
- Physician confirmation
Read Back of order
Describe the required **procedurefor relieving someone forabreakor at the the end ofashift.**
- Hand off Procedure
- Read Back of case events
- Time out
- End of shift report
Hand off Procedure
Hand washing duration
- 10 seconds
- 15 seconds
- 20 seconds
- 25 seconds
15 seconds
When there is no visible soiling on hands what is the preferred hand sanitizing method?
- Washing with soap and water for 10 seconds
- Washing with soap and water for 15 seconds
- Alcohol based hand sanitizer
- Washing with soap and water followed by alcohol based hand sanitizer
Alcohol based hand sanitizer
“Time out” confirms which of the following prior to surgery:
- Electrode Placement, Surgery & Impedance
- Monitoring Type (EEG or EP), Surgery & Surgery
- Patient, Surgery & Side of Surgery
- Patient, monitoring (EEG\EP) & Surgery
- Patient
- Surgery
- Side of Surgery
Patient care and supervision for EEG, LTM & cEEG diagnostic lab is defined by:
- ACNS
- ABRET
- ASET
- ASNM
ACNS
ACNS stands for:
- AMERICAN CLINICAL NEUROLOGY SOCIETY
- AMERICAN CENTRAL NEUROMONITORING SOCIETY
- ASSOCIATION of CLINICAL NEUROPHYSIOLOGY STUDIES
- AMERICAN CLINICAL NEUROPHYSIOLOGY SOCIETY
AMERICAN CLINICAL NEUROPHYSIOLOGY SOCIETY
Treat patients in an ethical fashion & do not discriminate
- ACNS GUIDELINES
- ABRET CODE OF ETHICS
- ASET PRACTICE GUIDELINES
- AAN CODE OF ETHICS
ABRET - CODE OF ETHICS
Do not divulge information from the exam
- ACNS GUIDELINES
- ABRET CODE OF ETHICS
- ASET PRACTICE GUIDELINES
- AAN CODE OF ETHICS
ABRET - CODE OF ETHICS
If a patient has a seizure during EEG recording, you should:
- Continue recording
- Call a code and assist the patient at bedside
- Discontinue recording & call a code
- Insert a tongue depressor in the patients mouth and turn pt. on side
Continue recording
The current CPR: Chest compression to rescue breath ratio is:
30:2
What is does RAWOD stand for
Regional Attenuation Without Delta
Describe this pattern seen in a 68 year old patient following clamping of the left middle cerebral artery.

RAWOD (Regional Attenuation Without Delta)

Describe Heschl’s gyrus
A convolution of the temporal lobe that is the cortical center for hearing and runs obliquely outward and forward from the posterior part of the lateral sulcus. Included as part of the primary auditory cortex.
What area is #1 indicating

Heschl’s gyrus

Brodmann area 44
Broca’s area

Brodmann Area 45
Broca’s area

Brodmann area 22
Wernicke’s area

Which electrode pair is most likeley to correspond to Broca’s area
- 15 & 16
- 21 & 22
- 33 & 34
- 46 & 47

33 & 34

Which electrode pair is most likeley to correspond to Werneckie’s area
- 47 & 48
- 28 & 29
- 59 & 60
- 31 & 32

47 & 48

What is MELAS syndrome
Mitochondrial myopathy, Encephalomyopathy, Lactic Acidosis, and Stroke-like episodes
MELAS is one of the family of mitochondrial cytopathies. It is aused by defects in the mitochondrial genome which is inherited purely from the female parent
What types of seizures would you see in Todd’s Paralysis
Partial
Clonic
Focal
Explain Eyeball polarity
**Cornea **(front of the eye) is positive
**retina **(back of the eye) is negative
this forms a dipole
this dipole movment produces eye movment artifact
Polarity of the tounge
- *positive** at root (back of tounge)
- *negative** at tip
Where is Heschl’s Gyrus is located
(Transverse Temporal Gyri)
- Primary auditory cortex
- Brodmann’s area 41&42
- Temporal lobe

Which electrode inicates the location of the primary somatosensory cortex
- 2
- 3
- 4
- 5

4

Define Beneficence
When doing research, studies or clinical trials, the welfare of the patient should always be one of the goals.
Seizure classifications associated with Todd’s Paralysis.
- Partial
- Clonic
- Focal
Febrile Seizures (West Syndrome) typically evolves into what?
Lennox Gastaut
When you have no visible soiling on your hands, what is the preferred method of hand sanitation?
- Alcohol based hand sanitizer
- Soap & water for 30 seconds
- Soap & water for 1 minute
- Soap & water for 15 seconds
Alcohol based hand sanitizer
Define Slow Wave
- Frequency: 0 - 4 Hz
- Duration: **> **300 msec
Define Sharp Wave
- Frequency: 5 - 14 Hz
- Duration: 70 - 200 msec
Define a Spike
- Frequency: 14 -50 Hz
- Duration: 20 - 70 msec
Define Triphasic waves
- Generalized
- Anteriorly predominant
- Anterior to posterior lag
- 100 - 300 uV
- 150 - 250 msec
- Periodic 1 - 2.5 /sec
Triphasic waves are frequently associated with what
- Creutzfeldt-Jakob
- Renal or hepatic encephalopathy
- Kidney or liver problems
Name this pattern

Triphasic waves

Derfine Burst Suppression
Variable (1 - 3 /sec) periods of spikes, polyspikes and sharp waves followed by periods of electrographic flattening.
Non-medically induced Burst suppression could be associated with:
- Drug overdose
- Reye’s Syndrome
- Hypothermia
- End stage: Sub-acute sclerosingpanencephalitis (SSPE)
- Poor prognosis (except in children)
What does FIRDA stand for
Frontal Intermittent Rhythmic Delta Activity
(Adults)

What does OIRDA stand for
Occipital Intermittent Rhythmic Delta Activity
(Pediatric)
Name this pattern

FIRDA
Frontal intermittent rhythmic delta

Common causes of PLEDS
- Herpes Encephalitis
- Stroke
- Tumor
- Focal lesion
What are PLEDS
Periodic Lateralized Epileptiform Discharges
Intermittent or continuous periodic biphasic or triphasic sharp waves or spikes on one side of the brain.
EEG with Cereberal Blood Flow (CBF) of 35 - 70
Normal
No Injury
**EEG **with Cereberal Blood Flow (CBF) of 25 - 35
Loses Beta Frequencies
Reversible
EEG with Cereberal Blood Flow (CBF) of **18 **- 25
Slowing to theta (5 -7 Hz)
Potentially Reversible
**EEG **with Cereberal Blood Flow (CBF) of **12 **- 18
Slowing to Delta (1 - 4 Hz)
Potentially Reversible
**EEG **with Cereberal Blood Flow (CBF) of <8 - 10
Complete suppression of all frequencies
Neuronal Death
Hyperlexia is commonly associated with which disorders or syndromes
- Autism
- Landau Kleffner