CLs OSCE Flashcards
CL AC Hx and symptoms
. Rfv
. Lee and last ac
. Vision: dv, iv, nv (fluctuating, does blinking affect va) - floads
. Current cls: confirm lens type, rx
. Wearing time: today and usual: /24, /7
. Comfort (lenses drying out, ocular discomfort, redness, pain)
. Hygiene/lens care – solution, regime, wash hands
. General health/allergies
. Medication
. Ocular history (ambl, strab, hes, recent infections)
. Lifestyle: driving, occupation, hobbies
CL fit Hx and symptoms
. Rfv
. Lee
. Motivation for cl wear
. Intended wt
. Lapsed/ new cl wearer
. If lapsed ask cl history: type of cls previously worn, any issues, reason for stopping
. Any lens/modality preferences
. Va with specs?
. General health/allergies
. Medication
. Ocular history (ambl, strab, hes, recent infection)
. Lifestyle: driving, occupation, hobbies
(Asymptomatic) infiltrative keratitis
. White spots in cornea (infiltrates)
. Causes: response to hypoxia, bacteria, lens deposits, allergic reaction,
Poor hygiene
. Signs: moderately red and slightly watery
. Symptoms: mild foreign body sensation, mild photophobia
. Management:
-Temporary discontinuation
-Most signs and symptoms resolve within 48 hours
-Infiltrates resolve over 2-3 weeks
-Advice against ew
-If reoccur, switch to dd
-Careful monitoring
-Ocular lubricants and cold compress for symptomatic relief
Superior epithelial arcuate lesion (SEAL)
. Causes: mechanical pressure due to design or material in the superior cornea, below superior eyelid
. Signs: arcuate staining parallel to superior limbus (from 10 o’clock to 2 o’clock)
. Symptoms: unilateral, asymmetric, mildly symptomatic, foreign body sensation, irritation
. Mostly seen in patient’s wearing high modulus silicone hydrogel contact lenses
. Management:
-Cease cl wear for 1-7 days (depends on severity)
-Lubricants for symptomatic relief
-Review lens fit or material (use thinner, more flexible lens material)
Contact lens associated papillary conjunctivitis (CLPC)
. Causes: conjunctival inflammation, immunological response due to hypersensitivity to lens deposits or solution or mechanical response due to lens design or modulus
Symptoms early stages: discomfort towards the end of the day, itching,
Mucous on waking
Symptoms later stages: excessive discomfort, itching,
Lens movement as lens gets stuck to papillae
. Common in atopic patients (ask about gh
Clpc management:
. If grade > 2 (cease lens wear, lens wear can continue if symptoms permit, improve lens hygiene)
. Alter the lens material
. Replacing the lens more frequently
. Treating mgd
. Ocular lubricants for symptomatic relief
. Reducing wearing time
. Suspending or ceasing lens wear
Contact lens red eye (CLARE)
. Cause: inflammatory response of cornea and conjunctiva subsequent to period of eye closure with CL wear, due to endotoxins from gram negative bacteria
Signs: unilateral, acute hyperaemia, diffuse infiltrative keratitis, possibly AC
Reaction, VA unaffected
. Symptoms: itching, congestion, pain indicates corneal involvement,
Woken at night with painful red eye
. Risk factors: upper respiratory tract infection, high water content cls, tightly fitted cls due to minimal movement which decrease tear lens exchange
ASK ABOUT RECENT ILLNESS
. Management:
-Cease lens wear
-Self-limiting
-Temporary discontinuation CL wear
-Careful monitoring
-Advice risk of recurrence is 50-70%
Abrasion
Causes: insertion and removal, fingernails, due to lens imperfection
Symptoms: FB sensation, discomfort and pain, photophobia
Management: remove cause and cease lens wear for 24hrs
Desiccation
Causes: localised disruption of the corneal surface, incomplete blinking
Signs: punctate fluorescein staining often inferior band
Symptoms: dryness symptoms
Management: refit lens and use lubricants
Neovascularisation
Causes: due to hypoxia or lactic acid build up due to restricted venous drainage by a steep fitting lens
Management: high DK/t lens, decrease WT, steroids, or surgical intervention
Dellen
Causes: caused by localised dryness and desiccation
Signs: possible scarring, vascularisation, 3 and 9 o’clock staining
Management: eliminate cause
Oedema
Causes: increase in tissue fluid
Signs: striae (fine wispy white lines), haze (loss of corneal transparency)
Symptoms: degradation of vision
Management: increase DK/t and reduce WT
Keratitis
Inflammation of cornea
- Infections (bacterial, viral, protozoal, fungal)
- Non-infectious (inflammatory, exposure, latrogenic-caused by medical treatment)
Microbial keratitis
Causes: bacteria, fungi, viruses, protozoa
Risk factors: trauma, contact lens wear, surgery, ocular surface disease,
immunosuppression
Symptoms: FB sensation, worse on removal of lens, pain mild to severe, redness,
severe photophobia, discharge, blurred vision, awareness of yellow/white spot,
unilateral
Signs: lid oedema, epiphora, discharge, conjunctival hyperaemia, central corneal lesion, stromal infiltration beneath lesion, AC cells and flare
DD: sterile infiltrative keratitis (CLPU)
Management: emergency referral due to sight threatening nature
- bacterial keratitis: 60-90% of all microbial keratitis
. Caused by gram +ve and gram -ve microorganisms
. Risk factors: EW, poor hygiene, non-contact lens wearers (immunosuppression,
Ocular surface disease, trauma)
. Signs: infiltrate (generally central, large>1mm, full thickness epithelial loss), severe hyperaemia, AC reaction (cells, flare to hypopyon), lid oedema
. Symptoms: unilateral, moderate to severe pain, reduced vision depends on location, photophobia
. Management:
-Refer to A and E
-Immediately cease lens wear
-Corneal scrape or biopsy (take cl case to hospital) to determine which microorganism
-Intensive anti-microbial treatment such as fluroquinolone
-Close monitory
- Acanthamoeba keratitis
. Acanthamoeba is a free-living amoeba (protozoa) commonly found in living water,
It can cause a parasitic infection mostly seen in CL wearers, 90% occurs in SCL
. Risk factors: swimming or showering in lenses or use of tap water in cleaning regimes
. Symptoms: very painful, decreased vision, FB sensation, photophobia, tearing and
Discharge
. Signs: often diagnosed as HSV, radial perineuritis, anterior stromal infiltrates, AC activity, eventually ring infiltrates
. DD: in early stages dry eyes, HSV keratitis, recurrent corneal erosion, CL associated keratitis, bacterial, fungal, viral, or sterile keratitis
. Management: emergency referral due to sight threatening, biopsy and culture
. Prognosis: worse than any other infective keratitis unless caught early
- fungal keratitis
. Causes: very rare in the UK, typical in tropical/warm countries, caused by moulds, suspect if following trauma whilst gardening
. Clinical features: similar to bacterial keratitis
. Management: antifungals
- Keratitis caused by virus most common (HSV, VZV)
- Herpes simplex virus (HSV)
. primary/recurrent/congenital
. most HSV-1
Symptoms: unilateral, pain, photophobia, reduced VA, redness
Signs: punctate lesion coalescing into dendriform pattern, AC,
Raised IOP, keratic precipitates, geographical ulcer
DD: Herpes zoster keratitis, bacterial keratitis
Management: acute or recurrent HSK with no stromal involvement (urgent referral within 1 week), if stromal involvement in child or CL wear (emergency), topical ganciclovir
- Herpes zoster keratitis (HSK)
. Ophthalmic shingles (corneal involvement in 65%)
. Refer immediate GP (skin lesions) or one week (deep, uveitis,
IOP raised)
- marginal keratitis
. Causes: inflammatory response to bacterial toxins on lids
. Non-infective
. Signs: accumulation/infiltration of white cells, epithelial defect/staining
. Management: refer, topical steroids and antibiotics, lid hygiene
- contact lens peripheral ulcer (CLPU)
. Causes: corneal response to bacterial toxins, immunological reactions, inflammation,
Sleeping with contact lenses
. Symptoms: eye moderately red or slightly watery, mild fb sensation better on
Lens removal, mild photophobia
. Signs: peripheral anterior stromal infiltrate, single or multiple, small>1.0mm,
Mild hyperaemia, epiphora, ac quiet or mildly inflamed, no lid oedema, usually unilateral
Ask about discharge, itchiness, cl wear, poh including surgery
. Dd: microbial keratitis, marginal keratitis, corneal scar, herpes simplex keratitis
Management: discontinue lens wear – most resolve within 48hrs, infiltrates resolve over 2-3 weeks, no ew, possibility of recurrence, examined daily for a week, no need to refer (only if unsure about mk), if no healing after 3-4 days refer – ocular lubricants, lid hygiene
Differential of infective vs non-infective (P.E.D.A.L.S)
. PAIN
-infective: intense worse on removal
-non-infective: little/absent relieved on lens removal
. EPITHELIUM
- infective: deep if ulcer
-non-infective: staining of overlying infiltrate
. DISCHARGE
-infective: muco-purulent discharge
-non-invective: none
. ANTERIOR CHAMBER
-infective: flare and cells from active infection
-non-infective: no signs
. LOCATION
-infective: single located centrally
-non-infective: multiple or single in the periphery
. SIZE
-infective: larger >1mm
-non-infective: small <1mm
CL TYPES
- RGP (Toric GP/Multifocal GP/spherical GP)
- soft (multifocal/Toric soft/spherical soft)
- Hybrids (scleral/scleral multifocals, ortho-k)
RGP vs SCL
. Rgp
-Better vision
-Corneal irregularity
-Dry eyes
-Compliance
-Scl failure
. Scl
-Comfort
-Infrequent wear
-Environment
-Rgp failure including fitting problems
Properties of CL materials
oxygen transmissibility (DK/t): amount of oxygen passing through a contact lens of specified thickness over a set amount of time and pressure difference
. Low DK/t can result in corneal changes: oedema, microcysts, blebs
Wettability: the ability of a drop of liquid to adhere to a solid surface
. greater wettability= improved vision and comfort and deposit resistance
Modulus: how well does the material resist deformation by pulling or stretching
. higher modulus= stiffer and better resistance to deformation, but px may complain of FB sensation due to stiffer lens material
Refractive index:
. increased refractive index = thinner lenses
Specific gravity: could be used to control RGP centration on cornea
RGP lens materials
- PMMA
Advantages: Great stability, No deposits, low weight
Disadvantages: Zero DK, causes hypoxia, oedema, and central corneal clouding - silicone acrylates
Silicone added to increase Dk
e.g. Boston IV, Dk 26
. more protein deposits
. generally lower Dk values
. poor wettability - Fluorosilicone acrylates
. Fluorine increase Dk
. Higher SA content improves DK, but often reduces wettability
e.g. Boston ES, DK 31 and Boston XO, Dk 100
. improved wettability
. more prone to lipid deposits, little protein deposits
FSA versus SA
Advantages
-increased oxygen permeability
-less hydrophobic
-less protein deposits
Disadvantages
-less stable
-more lipid
-higher modular weight
SCL materials
Low water content hydrogel material signs: limbal hyperaemia, neovascularisation. Epithelial microcysts, stromal striae
Higher water content of SCLs is important for oxygen to pass through the material to the cornea
. Advantages: high water content is great for health of the eye
. Disadvantage: dehydration causes significant corneal staining especially in thin lenses
. lens feels dry towards the end of the day due to dehydration
. it attracts more lens deposits
- silicone hydrogel (SiHy)
Blend hydrogel characteristics (wetting, comfort, movement) with silicone characteristic (high oxygen permeability= less hypoxia)
Advantages of SiHy
. high oxygen permeability= less hypoxia
-less hyperaemia, less limbal injection, less vascularization, less corneal oedema, better comfort
Disadvantages of SiHy
. maximum oxygen permeability, but not always maximum comfort, increased modulus, possible FB sensation due to stiffer material
. high modulus: stiff material: discomfort= SEAL mechanical
. low modulus: poorer handling
. more prone to lipid deposition
Which SCL material to choose?
. more oxygen = SiHy
. if EW or CW = SiHy
. deposits (lipids attracted to SiHy; proteins attracted Hy)
RGP
-Good visual acuity and contrast sensitivity, good for people with high corneal astigmatism
RGP materials
. High Dk/t allows more oxygen to the eye = improves health of eye= less corneal/limbal vascularization
. High Dk/t = less stable on cornea, more prone to deposits
RGP designs
Spherical: Bi curve C2, Tri curve C3, multicurve – change any curve
Aspherical
RGP lens fitting
. Trial lens based on keratometry reading
. TD=1.5 - 2.0mm smaller than HVID
. calculate corneal astigmatism: 0.05mm=0.25D or 0.1mm=0.5D
BOZR and Fluorescein pattern
. Rule of thumb: smallest change to make clinically significant impact: 0.1 mm
. If you see air bubble in centre: 0.3 mm flatter
BOZD
. should be 1.50mm larger than pupil size
. if pupils larger than BOZD, px will experience visual disturbances
. large BOZD= less flare/haloes