Clotting factors Flashcards
Explain the normal clotting process
- blood vessels are damages
- they constrict to limit blood flow
- platetlts stick and start to ahdhere this is platlet adhesion, and soon as more adher it’s called platelt aggregation
- surface of these plattelst provides a site for blood clotting to occur. clotting proteins are activated and to from a mesh-like fibrin clot
what happens in hemophilia?
incomplete formation of the plattelt plus and then of the fibrin clot
what is fribin made of?
thrombin and fibrinopeptide a and b
what kind of disorder is it? charcteerized by what?
a hereditray bleeding disorder
charcterized by impaired coagulation of the blood
what chromosome is it carried on?
x - therefore it’s X linked
if a hemophic father marries a normal women what will be of the children?
normal son and carrier daughter
if a normal man marries a carrier women what happens to the children?
normal son, hemophlic son, normal daught, carrier daughter
what are the types of hemophilia?
A , B, C
how common is hemophilia?
1.25 of every 10, 000 live male births
who is famous carrier?
queen victoria