Clotrimazol Flashcards

1
Q

Mecanismo de acción

A

Inhibe la 14-a-esterol-desmetilasa perjudicando la biosíntesis de ergosterol

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2
Q

Indicaciones clínicas

A

Onicomicosis, Candidiasis, Pitiriasis Versicolor

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3
Q

Excreción

A

Renal y Biliar

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4
Q

Vida media de eliminación

A

3.5 - 5 hrs

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5
Q

Metabolismo

A

Hepático

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6
Q

Reacciones Adversas

A

Trastornos gastro intestinales, erupción cutánea, prurito

Vaginales; dispareunia, poliuria, irritación uretral

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7
Q

Categoría en el embarazo

A

B

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8
Q

Unión a proteínas plasmáticas

A

98%

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