Clopidogrel Flashcards
1
Q
Brand Name (Clopidogrel)
A
Plavix
2
Q
Drug Class (Clopidogrel)
A
Thienopyridine Antiplatelet
3
Q
Indications
Clopidogrel
A
STEMI*
Moderate to high risk NSTEMI*
Acute Coronary Syndrome
Substitute for Aspirin^
4
Q
Mechanism of Action
Clopidogrel
A
Inhibits platelet aggregation by blocking activation of the glycoprotein 2B/3A complex
5
Q
Contraindications
Clopidogrel
A
Active GI bleeding
Intracranial Hemorrhage
Known Hypersensitivity
6
Q
Adverse Effects (Clopidogrel)
A
Severe Neutropenia
Thromobic Thromobocytopenic Purpura (TTP)
GI Hemorrhage
Cerebral Hemorrhage
Angioedema
Stevens-Johnson Syndrome
Rash
Flulike Symptoms
7
Q
Precautions
Clopidogrel
A
Nexium and Prilosec (Proton pump inhibitors) may inhibit the effects of Plavix
8
Q
Dose
Clopidogrel
A
Adult
300-600mg : PO
Pedi
Not Recommended